AUTHOR=Baldini Nicola , De Milito Angelo , Feron Olivier , Gillies Robert J. , Michiels Carine , Otto Angela M. , Pastoreková Silvia , Pedersen Stine F. , Porporato Paolo E. , Sonveaux Pierre , Supuran Claudiu T. , Avnet Sofia 

TITLE=Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Metabolic Networks in Cancer

JOURNAL=Frontiers in Pharmacology

VOLUME=Volume 8 - 2017

YEAR=2017

URL=https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2017.00411

DOI=10.3389/fphar.2017.00411

ISSN=1663-9812

ABSTRACT=<p>Cancers are metabolic entities wherein cancer cells adapt their metabolism to their oncogenic agenda and microenvironmental influences. Metabolically different cancer cell subpopulations collaborate to optimize nutrient delivery with respect to immediate bioenergetic and biosynthetic needs. They can also metabolically exploit host cells. These metabolic networks are directly linked with cancer progression, treatment resistance and relapse. Conversely, metabolic alterations in cancer are exploited for anticancer therapy, imaging and personalized medicine. These topics were addressed at the 3rd annual meeting of the International Society of Cancer Metabolism (ISCaM) in Brussels, Belgium, on 26–29 October 2016.</p>