AUTHOR=Bai Xue , Zhang Meng 

TITLE=Traditional Chinese Medicine Intervenes in Vascular Dementia: Traditional Medicine Brings New Expectations

JOURNAL=Frontiers in Pharmacology

VOLUME=Volume 12 - 2021

YEAR=2021

URL=https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2021.689625

DOI=10.3389/fphar.2021.689625

ISSN=1663-9812

ABSTRACT=Vascular dementia (VD) is one of the most common types of dementia, referring to a group of symptoms that mainly manifest as advanced neurocognitive dysfunction caused by cerebrovascular disease (CVD). A large number of studies have shown that traditional Chinese medicine (TCM) has a clinical effect on VD and has broad prospects. There are many discussions on the pharmacological mechanisms of treating the kidney, eliminating turbidity, and promoting blood circulation. TCM has a prominent role improving patients’ cognitive function and quality of life. In this review, we summarize the pathogenesis of VD in modern medicine and TCM, traditional prescriptions, single-agent effective ingredients and their pharmacological mechanisms for treating VD, highlight the characteristics of TCM, and reveal the multi-targeted mechanism of TCM for treating VD.