AUTHOR=Guo Bindan , Dong Wenting , Huo Jinhai , Sun Guodong , Qin Zhiwei , Liu Xiaodong , Zhang Bihai , Wang Weiming TITLE=Integrated Metabolomics and Network Pharmacology Analysis Immunomodulatory Mechanisms of Qifenggubiao Granules JOURNAL=Frontiers in Pharmacology VOLUME=Volume 13 - 2022 YEAR=2022 URL=https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.828175 DOI=10.3389/fphar.2022.828175 ISSN=1663-9812 ABSTRACT=Qifenggubiao granules (invention patent number: CN1325098C, approval number: Sinopharm Zhunzi B20020410) is a new Chinese medicine independently developed by Heilongjiang Academy of Traditional Chinese Medicine, which combines the essence of Yupingfeng powder and Shengmaiyin , and has been included in the 2020 edition of Chinese Pharmacopoeia. It has remarkable pharmacodynamic results and conclusive clinical effects in the treatment of respiratory diseases such as allergic rhinitis and chronic cough. Previous pharmacological studies have shown that it has immunomodulatory effect, but its immunomodulatory mechanism is still unclear.