AUTHOR=Guo Bindan , Dong Wenting , Huo Jinhai , Sun Guodong , Qin Zhiwei , Liu Xiaodong , Zhang Bihai , Wang Weiming 

TITLE=Integrated Metabolomics and Network Pharmacology Analysis Immunomodulatory Mechanisms of Qifenggubiao Granules

JOURNAL=Frontiers in Pharmacology

VOLUME=Volume 13 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.828175

DOI=10.3389/fphar.2022.828175

ISSN=1663-9812

ABSTRACT=Qifenggubiao granules (invention patent number: CN1325098C, approval number: Sinopharm Zhunzi B20020410) is a new Chinese medicine independently developed by Heilongjiang Academy of Traditional Chinese Medicine, which combines the essence of Yupingfeng powder and Shengmaiyin , and has been included in the 2020 edition of Chinese Pharmacopoeia. It has remarkable pharmacodynamic results and conclusive clinical effects in the treatment of respiratory diseases such as allergic rhinitis and chronic cough. Previous pharmacological studies have shown that it has immunomodulatory effect, but its immunomodulatory mechanism is still unclear.