AUTHOR=Abdelrahim Maen , Esmail Abdullah , Al Saadi Noor , Zsigmond Eva , Al Najjar Ebtesam , Bugazia Doaa , Al-Rawi Hadeel , Alsaadi Ayat , Kaseb Ahmed O. 

TITLE=Thymoquinone’s Antiviral Effects: It is Time to be Proven in the Covid-19 Pandemic Era and its Omicron Variant Surge

JOURNAL=Frontiers in Pharmacology

VOLUME=Volume 13 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.848676

DOI=10.3389/fphar.2022.848676

ISSN=1663-9812

ABSTRACT=The COVID-19 pandemic has impacted every country in the world. With more than 290 million cases and more than 5 million deaths. The FDA either approved or authorized the emergency use for three vaccines against COVID-19. The treatment options of COVID-19 are very limited. There are multiple complementary and alternative medicine modalities that were suggested to be efficacious in the treatment of COVID-19 such as Thymoquinone. The effects of Thymoquinone have been examined and multiple studies indicate a promising beneficial effect. However, the current body of research is limited in terms of its scope, quality, and quantity. While higher-quality studies are required, physicians do not routinely recommend the use of marketed supplements of natural products, including Thymoquinone for COVID-19. Given the numerous suggested positive effects of Thymoquinone, including anti-inflammatory and antimicrobial properties, additional research is required to confirm or refute these promising benefits. Complementary and alternative medicine is an area that requires additional evidence-based practice and research to confirm effects observed in clinical practice.