AUTHOR=Yuan Shuo , Li You , Li Jiao , Xue Jia-Chen , Wang Qi , Hou Xiao-Ting , Meng Huan , Nan Ji-Xing , Zhang Qing-Gao TITLE=Traditional Chinese Medicine and Natural Products: Potential Approaches for Inflammatory Bowel Disease JOURNAL=Frontiers in Pharmacology VOLUME=Volume 13 - 2022 YEAR=2022 URL=https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.892790 DOI=10.3389/fphar.2022.892790 ISSN=1663-9812 ABSTRACT=Inflammatory bowel disease (IBD) is a chronic, recurrent and intractable inflammatory disease of the gastrointestinal tract, usually accompanied by inflammatory cell infiltration and damage to the intestinal mucosa and carries a particular risk of cancer. The clinical use of drugs in western countries affects IBD treatment, but various adverse effects and high prices limit their application. For these reasons, Traditional Chinese Medicine (TCM) is more advantageous in treating IBD. This paper reviews the mechanism and research status of TCM and natural products in IBD treatment by analyzing the relevant literature to provide a scientific and theoretical basis for IBD treatment.