AUTHOR=Wang Hang , Dong Xianghuan , Awan Maher Un Nisa , Bai Jie 

TITLE=Epigenetic mechanisms involved in methamphetamine addiction

JOURNAL=Frontiers in Pharmacology

VOLUME=Volume 13 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.984997

DOI=10.3389/fphar.2022.984997

ISSN=1663-9812

ABSTRACT=Methamphetamine (METH) is an illicit psychostimulant widely abused. The molecular mechanism of METH abuse is complicated and still unknown. METH causes the release of the neurotransmitters including dopamine, glutamate, norepinephrine and serotonin, which activate various brain areas in the central nervous system. METH can also lead to synaptic plasticity and pathological memory enhancement. Epigenetics is involved in METH addiction. This paper will briefly summarize the studies on epigenetics related to METH addiction.