AUTHOR=Albouy Marion , Aubailly Simon , Jeanneton Olivier , Marteau Clarisse , Sobilo Lauren , Boulgana Rachid , Bru Gerard , Bellanger Marine , Leblanc Emmanuelle , Dos Santos Morgan , Pays Karl , Choisy Patrick , Bossard Elodie , Nizard Carine , Thepot Amelie , Gourguillon Lorene , Bulteau Anne-Laure TITLE=Skin-protective biological activities of bio-fermented Aframomum angustifolium extract by a consortium of microorganisms JOURNAL=Frontiers in Pharmacology VOLUME=Volume 14 - 2023 YEAR=2023 URL=https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2023.1303198 DOI=10.3389/fphar.2023.1303198 ISSN=1663-9812 ABSTRACT=Background: Aframomum sp. is a genus of plants in the Zingiberaceae family. It includes several species, some of which are used in cosmetics for their various properties, making them useful in skincare products, particularly for anti-aging, moisturizing, and brightening the skin.However, to date, there is no experimental evidence on its natural extracts obtained or modified using microorganisms (bio-fermentation) as an anti-aging agent.Objective: The present study aimed to evaluate the antiaging effect of a Bio-fermented Aframomum angustifolium (BAA) extract on 3D bioprinted skin equivalent.The consortium of microorganisms contained Komagataeibacter, Gluconobacter,