AUTHOR=Alharbi Bandar , Qanash Husam , Almashjary Majed N. , Barnawi Heba , Aldarhami Abdu , Alsaif Ghaida , Alsamaan Fahad , Monjed Mohammad Khalil , Al Shmrany Humood , Bazaid Abdulrahman S. 

TITLE=Watercress oil loaded with gel: evaluation of hemolysis inhibition, antioxidant, antimicrobial, and healing properties

JOURNAL=Frontiers in Pharmacology

VOLUME=Volume 15 - 2024

YEAR=2024

URL=https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2024.1424369

DOI=10.3389/fphar.2024.1424369

ISSN=1663-9812

ABSTRACT=Plant-derived compounds are renowned for their remarkable pharmacological properties, holding immense promise for therapeutic interventions in human health. In this study, we aimed to assess the antimicrobial, anti-hemolytic, antioxidant, and wound healing attributes of watercress oil incorporated into Vaseline gel (OLG) compared to watercress oil alone. OLG was formulated through a meticulous process involving the addition of Vaseline gel to the oil under agitation conditions. High-performance liquid chromatography analysis of watercress oil unveiled a rich array of phenolic compounds, including gallic acid (10.1821 µg/mL), daidzein (3.46 µg/mL), and hesperetin (3.28 µg/mL). The inhibitory zones caused by watercress oil alone against a spectrum of pathogens, including Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Enterococcus faecalis, and Candida albicans, were measured at 25±0.