AUTHOR=Noguchi Yoshihiro , Tachi Tomoya , Yoshimura Tomoaki TITLE=Is it appropriate to conduct a disproportionality analysis using a spontaneous reporting database to investigate whether drug-related adverse events are dose-dependent? JOURNAL=Frontiers in Pharmacology VOLUME=Volume 16 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2025.1563524 DOI=10.3389/fphar.2025.1563524 ISSN=1663-9812