AUTHOR=Yu Xihui , Chen Xiaotong , Yan Xia , Wu Xuejun , Zhang Yizhi , Luo Xiajiong , Ma Weihao , Fu Hongbo , Zhang Yaofeng TITLE=Research on strategies for enhancing drug knowledge dissemination on Chinese social media WeChat public accounts based on text mining technology JOURNAL=Frontiers in Pharmacology VOLUME=Volume 16 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2025.1569863 DOI=10.3389/fphar.2025.1569863 ISSN=1663-9812 ABSTRACT=ObjectiveHealth science popularization is an important means to improve public health literacy, promote healthy lifestyles, prevent diseases and respond to health crises, which is of great significance for improving the overall health of the people. Strengthening the medication education of patients is also one of the key factors to improve patients’ medication adherence. In order to strengthen the dissemination of pharmaceutical popular science articles and give full play to the value of pharmaceutical popular science, this study takes WeChat public account as the research platform to explore effective strategies to improve pageviews of science popularization. It provides references for science popularization workers, so that science popularization can play a better role in improving the public’s knowledge of medication safety.MethodsTaking the well-known pharmaceutical science popularization WeChat account “PSM Medicine Shield Public Welfare” as an example, we combined the Term Frequency-Inverse Document Frequency (TF-IDF) algorithm and VOSviewer visualization analysis technology to construct a hot topic analysis model for pharmaceutical science popularization articles, and analyzed the common rules and characteristics of successful hot articles. Latent Dirichlet Allocation (LDA) and The Bidirectional Encoder Representations from Transformers Topic (BERTopic) model were used to realize the construction of the topic model.ResultsThe model selected the top 20% of popularization articles with the greatest reading volume between 2015 and 2023 as the database for text mining. The clustering results indicated that the public was interested in these five types of pharmaceutical science popularization themes: drug dosage, drug side effects, children’s infections, the efficacy of traditional Chinese medicine and Chinese patent medicines, and the usage methods of different drug administration routes. The public’s interest in topics changed from drug side effects to practical drug usage issues, as seen by the keyword time series graph.ConclusionPharmaceutical professionals may more effectively discover hot themes in the industry by combining the TF-IDF algorithm with VOSviewer visualization analysis and LDA and BERTopic in the text mining. This improves the readability of popularization articles and the impact of WeChat accounts, which may improve medication adherence and raise public awareness of medication usage.