AUTHOR=Alasmari Fawaz , Ahmad Ashfaq , Alsanea Sary , Hammad Alaa M. , Al-Qerem Walid TITLE=Current insights and prospects for the pathogenesis and treatment of clinical manifestations associated with Down syndrome through neurotransmitter, inflammatory, and oxidative stress pathways JOURNAL=Frontiers in Pharmacology VOLUME=Volume 16 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2025.1592277 DOI=10.3389/fphar.2025.1592277 ISSN=1663-9812