Opinion

Published on 12 Jun 2024

Relative efficacy of five SGLT2 inhibitors: a network meta-analysis of 20 cardiovascular and respiratory outcomes

in Experimental Pharmacology and Drug Discovery

LiGang Huang
Rong Hu
HaiTao Zou

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1419729

479 views

Systematic Review

Published on 11 Jun 2024

In silico approaches for drug repurposing in oncology: a scoping review

in Experimental Pharmacology and Drug Discovery

Bruno Raphael Ribeiro Cavalcante
Raíza Dias Freitas
Leonardo de Oliveira Siquara da Rocha
Roberto de Souza Batista Dos Santos
Bruno Solano de Freitas Souza
Pablo Ivan Pereira Ramos
Gisele Vieira Rocha
Clarissa Araújo Gurgel Rocha

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1400029

656 views

Original Research

Published on 11 Jun 2024

Deciphering the therapeutic potential of trimetazidine in rheumatoid arthritis via targeting mi-RNA128a, TLR4 signaling pathway, and adenosine-induced FADD-microvesicular shedding: In vivo and in silico study

in Experimental Pharmacology and Drug Discovery

Enas Omran
Abdullah R. Alzahrani
Samar F. Ezzat
Ghada Ellithy
Marwa Tarek
Eman Khairy
Mohamed M. Ghit
Ahmed Elgeushy
Tahani Mohamed Ibrahim Al-Hazani
Ibrahim Abdel Aziz Ibrahim

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1406939

508 views

Original Research

Published on 11 Jun 2024

Evaluation of the synergistic effects of curcumin-resveratrol co-loaded biogenic silica on colorectal cancer cells

in Experimental Pharmacology and Drug Discovery

Adriana Ochoa-Sanchez
Padmavati Sahare
Surajit Pathak
Antara Banerjee
Miriam Estevez
Asim K. Duttaroy
Gabriel Luna-Bárcenas
Sujay Paul

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1341773

435 views

Original Research

Published on 10 Jun 2024

Sputum microbe community alterations induced by long-term inhaled corticosteroid use are associated with airway function in chronic obstructive pulmonary disease patients based on metagenomic next-generation sequencing (mNGS)

in Experimental Pharmacology and Drug Discovery

Yuanyi Yue
Baohui Zhang
Zhong He
Yuling Zheng
Xueqing Wang
Qiang Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1323613

312 views

Review

Published on 07 Jun 2024

Improving the treatment of bacterial infections caused by multidrug-resistant bacteria through drug repositioning

in Experimental Pharmacology and Drug Discovery

Paulina Glajzner
Agnieszka Bernat
Magdalena Jasińska-Stroschein

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1397602

529 views

Original Research

Published on 07 Jun 2024

Pre-clinical studies comparing the anti-inflammatory potential of artemisinic compounds by targeting NFκB/TNF-α/NLRP3 and Nrf2/TRX pathways in Balb/C mice

in Experimental Pharmacology and Drug Discovery

Syeda Tayyaba Batool Kazmi
Humaira Fatima
Iffat Naz
Nosheen Kanwal
Ihsan-ul Haq

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1352827

431 views

Original Research

Accepted on 06 Jun 2024

Wogonin protects against bleomycin-induced mouse pulmonary fibrosis via the inhibition of CDK9/p53-mediated cell senescence

in Experimental Pharmacology and Drug Discovery

Libo Wang
Fei Lin
Youli Liu
Wei Li
Qingjie Ding
Xulei Duan
Lin Yang
Zhengyu Bai
Min Zhang
Yuming Guo

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1407891

Mini Review

Published on 06 Jun 2024

The emerging role and clinicopathological significance of MFSD12 in cancer and lysosomal storage diseases

in Experimental Pharmacology and Drug Discovery

Liqiong Ding

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1398320

301 views

Review

Published on 04 Jun 2024

Exploring orphan GPCRs in neurodegenerative diseases

in Experimental Pharmacology and Drug Discovery

Devrim Öz-Arslan
Melis Yavuz
Beki Kan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1394516

764 views

Original Research

Published on 04 Jun 2024

The autophagic regulation of rosiglitazone-promoted adipocyte browning

in Experimental Pharmacology and Drug Discovery

Yue Li
Wanqing Zheng
Xinhang Li
Zhengwei Lue
Yun Liu
Jiaying Wu
Xiangnan Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1412520

445 views

Review

Published on 03 Jun 2024

Reflections on the regulatory field covering the development of paediatric medicinal products: a brief overview of current status and challenges

in Experimental Pharmacology and Drug Discovery

Birka Lehmann

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1375988

312 views

Review

Published on 03 Jun 2024

Kratom safety and toxicology in the public health context: research needs to better inform regulation

in Experimental Pharmacology and Drug Discovery

Jack E. Henningfield
Oliver Grundmann
Marilyn A. Huestis
Kirsten E. Smith

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1403140

947 views

Original Research

Published on 03 Jun 2024

The impact of abstinence from chronic alcohol consumption on the mouse striatal proteome: sex and subregion-specific differences

in Experimental Pharmacology and Drug Discovery

Brittnie-lee M. Duffus
David L. Haggerty
Emma H. Doud
Amber L. Mosley
Bryan K. Yamamoto
Brady K. Atwood

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1405446

413 views

Review

Accepted on 31 May 2024

The role of cGAS in epithelial dysregulation in inflammatory bowel disease and gastrointestinal malignancies

in Experimental Pharmacology and Drug Discovery

Anna Ramos
Nazih Bizri
Kevin P. Mollen
Sidrah Khan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1409683

Review

Published on 30 May 2024

Re-evaluation of the cardioprotective effects of cannabinoids against ischemia-reperfusion injury according to the IMproving Preclinical Assessment of Cardioprotective Therapies (IMPACT) criteria

in Experimental Pharmacology and Drug Discovery

Anna Pędzińska-Betiuk
Eberhard Schlicker
Jolanta Weresa
Barbara Malinowska

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1382995

376 views

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Articles

Relative efficacy of five SGLT2 inhibitors: a network meta-analysis of 20 cardiovascular and respiratory outcomes

In silico approaches for drug repurposing in oncology: a scoping review

Deciphering the therapeutic potential of trimetazidine in rheumatoid arthritis via targeting mi-RNA128a, TLR4 signaling pathway, and adenosine-induced FADD-microvesicular shedding: In vivo and in silico study

Evaluation of the synergistic effects of curcumin-resveratrol co-loaded biogenic silica on colorectal cancer cells

Sputum microbe community alterations induced by long-term inhaled corticosteroid use are associated with airway function in chronic obstructive pulmonary disease patients based on metagenomic next-generation sequencing (mNGS)

Improving the treatment of bacterial infections caused by multidrug-resistant bacteria through drug repositioning

Pre-clinical studies comparing the anti-inflammatory potential of artemisinic compounds by targeting NFκB/TNF-α/NLRP3 and Nrf2/TRX pathways in Balb/C mice

Wogonin protects against bleomycin-induced mouse pulmonary fibrosis via the inhibition of CDK9/p53-mediated cell senescence

The emerging role and clinicopathological significance of MFSD12 in cancer and lysosomal storage diseases

Exploring orphan GPCRs in neurodegenerative diseases

The autophagic regulation of rosiglitazone-promoted adipocyte browning

Reflections on the regulatory field covering the development of paediatric medicinal products: a brief overview of current status and challenges

Kratom safety and toxicology in the public health context: research needs to better inform regulation

The impact of abstinence from chronic alcohol consumption on the mouse striatal proteome: sex and subregion-specific differences

The role of cGAS in epithelial dysregulation in inflammatory bowel disease and gastrointestinal malignancies

Re-evaluation of the cardioprotective effects of cannabinoids against ischemia-reperfusion injury according to the IMproving Preclinical Assessment of Cardioprotective Therapies (IMPACT) criteria