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Pharmacology of Ion Channels and Channelopathies publishes articles concerning all aspects of ion channels, pharmacology and channelopathies. In this regard we are interested in studies on genetics, molecular and cellular systems, and organisms, as well as novel drug screening and new therapies.
Pharmacology of Ion Channels and Channelopathies publishes significant clinical and basic research articles dealing with all aspects of ion channels, pharmacology, and channelopathies. We are interested in studies such on genetics, molecular and cellular systems, and organisms, as well as novel drug screening and new therapies. Ion channels are transmembrane proteins participating in many, if not all, cellular functions, whereas dysfunction of ion channels are key events in many pathological processes. Channelopathies, which refer to monogenic disorders due to mutations in ion channel genes in its more stringent definition, have greatly contributed to our understanding of the physiological role of the various ion channels, and of the potential involvement of these channels in multigenic or acquired diseases. Importantly, ion channels are the main target of many drugs already used in many diseases, including for instance cardiovascular, central nervous system, and metabolic diseases. Intensive research is now conducted to develop new drugs selective for channel subtypes, and to resolve the intimate drug-channel interactions. Last but not least, ion channels are also the target of many toxicants, and pharmacogenomics highlights how polymorphisms/mutations in ion channel genes may alter therapy success. With a greater understanding of ion channel properties and pharmacology, together with the elucidation of primary and secondary channelopathies, ion channels will continue to present a growing substantial target of interest for the pharmaceutical sector.
Pharmacology of Ion Channels and Channelopathies offers a unique, highly efficient and transparent publication platform to the scientific community for the rapid dissemination of all innovative and valuable findings that cover the leading edge of the above-mentioned fields.
Indexed in: PubMed, PubMed Central, Scopus, Web of Science, Google Scholar, DOAJ, CrossRef, Chemical Abstracts Service (CAS)
Pharmacology of Ion Channels and Channelopathies welcomes submissions of the following article types: Book Review, Correction, Data Report, Editorial, General Commentary, Hypothesis and Theory, Methods, Mini Review, Opinion, Original Research, Perspective, Review, Specialty Grand Challenge and Technology and Code.
All manuscripts must be submitted directly to the section Pharmacology of Ion Channels and Channelopathies, where they are peer-reviewed by the Associate and Review Editors of the specialty section.
Articles published in the section Pharmacology of Ion Channels and Channelopathies will benefit from the Frontiers impact and tiering system after online publication. Authors of published original research with the highest impact, as judged democratically by the readers, will be invited by the Chief Editor to write a Frontiers Focused Review - a tier-climbing article. This is referred to as "democratic tiering". The author selection is based on article impact analytics of original research published in all Frontiers specialty journals and sections. Focused Reviews are centered on the original discovery, place it into a broader context, and aim to address the wider community across all of Pharmacology.
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