AUTHOR=Marín-Cascales Elena , Rubio-Arias Jacobo Á. , Alcaraz Pedro E. TITLE=Effects of Two Different Neuromuscular Training Protocols on Regional Bone Mass in Postmenopausal Women: A Randomized Controlled Trial JOURNAL=Frontiers in Physiology VOLUME=Volume 10 - 2019 YEAR=2019 URL=https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2019.00846 DOI=10.3389/fphys.2019.00846 ISSN=1664-042X ABSTRACT=Purpose: The aims of this study were to investigate the effect of 24 weeks of whole-body vibration and multi-component training on lumbar spine and femoral neck bone mass, and to define what type of training produces greater adaptations in postmenopausal women. Methods: A total of 38 women completed the study (Clinical Gov database ID: NCT01966562). Participants were randomly assigned to one of the study groups: whole-body vibration group (WBVG), multi-component training group (MTG) or control group (CG). The experimental groups performed a progressive 24-week training (3 sessions/week) program. Bone mineral density (BMD) and bone mineral content (BMC) at the lumbar spine and femoral neck were assessed by Dual-energy X-ray absorptiometry. Results: Significantly and clinically relevant increases in lumbar spine bone mass (BMD: p = 0.033; +5.15%; BMC: p = 0.050; +10.58%) were observed in WBVG. MTG showed clinically important pre-post changes on lumbar spine BMC (+7.78%), although there was no statistical significance (p = 0.141). At the femoral neck, no statistically significant increases on bone mass were obtained in either training group. No changes were shown in any of the bone parameters in the control participants. Conclusion: As there were no statistically significant differences between groups, it is not possible to determine which training protocol produces greater adaptations. In conclusion, 24 weeks of supervised WBV and MT may counteract the rapid loss of bone mass after the cessation of menstruation, thus improving postmenopausal women bone health.