AUTHOR=Zhao Lei , Lu Aijia , Tian Jie , Huang Jie , Ma Xiaohai TITLE=Effects of Different LVEF Assessed by Echocardiography and CMR on the Diagnosis and Therapeutic Decisions of Cardiovascular Diseases JOURNAL=Frontiers in Physiology VOLUME=Volume 11 - 2020 YEAR=2020 URL=https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2020.00679 DOI=10.3389/fphys.2020.00679 ISSN=1664-042X ABSTRACT=Aims: The impact of different left ventricular ejection fraction (LVEF) assessed by echocardiography (EC) and cardiac magnetic resonance (CMR) on clinical diagnosis and management that could be critical in clinical practice remains unclear. This study investigated this impact for patients who underwent both exams in a real-world clinical practice. Methods: 500 patients who underwent CMR and two-dimensional EC were retrospectively included in present study. EC-measured LVEF and CMR-measured LVEF were compared. A 50% cut-off of LVEF was chosen to assess the effect of the difference between these two modalities on disease diagnosis, and a 35% cut-off was chosen for disease management, respectively. For those patients who received device therapy or coronary artery bypass grafting (CABG), the study compared the LVEF between EC and CMR with the current guideline for therapy recommendation. Results: EC-LVEF and CMR-LVEF were positively correlated, but EC-LVEF was significantly larger than CMR-LVEF (P<0.001). Three patient groups were examined: (I) CMR-LVEF≥50%, (II) 35%