AUTHOR=Wang Boyuan , Chen Shanji , Song Jinfeng , Huang Dan , Xiao Gexin TITLE=Recent advances in predicting acute mountain sickness: from multidimensional cohort studies to cutting-edge model applications JOURNAL=Frontiers in Physiology VOLUME=Volume 15 - 2024 YEAR=2024 URL=https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2024.1397280 DOI=10.3389/fphys.2024.1397280 ISSN=1664-042X ABSTRACT=High-altitude illnesses, encompassing a spectrum of health threats including Acute Mountain Sickness (AMS), pose significant challenges to individuals exposed to high altitude environments, necessitating effective prophylaxis and immediate management. Given the variability in individual responses to these conditions, accurate prediction of high-altitude illnesses onset is of paramount importance. This review systematically consolidates recent advancements in research on predicting AMS by evaluating existing cohort data, predictive models, and methodologies, while also delving