AUTHOR=Jiang Zhengzheng , Shen YaWen TITLE=Multimodal learning for enhanced SPECT/CT imaging in sports injury diagnosis JOURNAL=Frontiers in Physiology VOLUME=Volume 16 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2025.1605426 DOI=10.3389/fphys.2025.1605426 ISSN=1664-042X ABSTRACT=IntroductionSingle-photon emission computed tomography/computed tomography (SPECT/CT) imaging plays a critical role in sports injury diagnosis by offering both anatomical and functional insights. However, traditional SPECT/CT techniques often suffer from poor image quality, low spatial resolution, and limited capacity for integrating multiple data sources, which can hinder accurate diagnosis and intervention.MethodsTo address these limitations, this study proposes a novel multimodal learning framework that enhances SPECT/CT imaging through biomechanical data integration and deep learning. Our method introduces a hybrid model combining convolutional neural networks for spatial feature extraction and transformer-based temporal attention for sequential pattern recognition. This study further incorporates a biomechanics-aware injury detection module (BID-Net), which leverages kinematic signals, motion data, and physiological context to refine lesion detection accuracy.ResultsExperimental results on a curated sports injury dataset demonstrate that our framework significantly improves image clarity, diagnostic precision, and interpretability over traditional approaches.DiscussionThe integration of biomechanical constraints and adaptive attention mechanisms not only enhances SPECT/CT imaging quality but also bridges the gap between AI-driven analytics and clinical practice in sports medicine. Our study presents a promising direction for intelligent, real-time diagnostic tools capable of supporting injury prevention, early detection, and rehabilitation planning in athletic care.