AUTHOR=Si Xiaojun , Yan Liang , Shi Cui , Xu Yang TITLE=LRU-Net: lightweight and multiscale feature extraction for localization of ACL tears region in MRI images JOURNAL=Frontiers in Physiology VOLUME=Volume 16 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2025.1611267 DOI=10.3389/fphys.2025.1611267 ISSN=1664-042X ABSTRACT=IntroductionAnterior cruciate ligament (ACL) injuries hold significant clinical importance, making the development of accurate and efficient diagnostic tools essential. Deep learning has emerged as an effective method for detecting ACL tears. However, current models often struggle with multiscale and boundary-sensitive tear patterns and tend to be computationally intensive.MethodsWe present LRU-Net, a lightweight residual U-Net designed for ACL tear segmentation. LRU-Net integrates an advanced attention mechanism that emphasizes gradients and leverages the anatomical position of the ACL, thereby improving boundary sensitivity. Furthermore, it employs a dynamic feature extraction module for adaptive multiscale feature extraction. A dense decoder featuring dense connections enhances feature reuse.ResultsIn experimental evaluations, LRU-Net achieves a Dice Coefficient Score of 97.93% and an Intersection over Union (IoU) of 96.40%.DiscussionIt surpasses benchmark models such as Attention-Unet, Attention-ResUnet, InceptionV3-Unet, Swin-UNet, Trans-UNet and Rethinking ResNets. With a reduced computational footprint, LRU-Net provides a practical and highly accurate solution for the clinical analysis of ACL tears.