AUTHOR=Dong Zhiyu , Zhao Le , Fan Yajun , Ma Haihua , Shao Changle , Zhang Yiran , Li Peng 

TITLE=GA-TongueNet: tongue image segmentation network using innovative DiFP and MDi for stable generalization ability

JOURNAL=Frontiers in Physiology

VOLUME=Volume 16 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2025.1617647

DOI=10.3389/fphys.2025.1617647

ISSN=1664-042X

ABSTRACT=Tongue is directly or indirectly connected to many internal organs in Traditional Chinese Medicine (TCM). In computer-aided diagnosis, tongue image segmentation is the first step in tongue diagnosis, and the precision of this segmentation is decisive in determining the accuracy of the tongue diagnosis results. Due to challenges such as insufficient available sample size and complex background, the generalization and robustness of current tongue segmentation algorithms are usually poor, which seriously hinders the practicality of tongue diagnosis. In this article, a GA-TongueNet, namely Tongue Segmentation Network for Stable Generalization Ability, based on self-attention architecture is proposed, which is a tongue segmentation network that can simultaneously have strong generalization ability and accuracy under small samples and diverse background conditions. Firstly, GA-TongueNet is built upon the transformer architecture, embedding the dilated feature pyramid (DiFP) module and the multi-dilated convolution (MDi) module proposed in this article. Secondly, the DiFP module is integrated to comprehend both the overall tongue image structure and intricate local details, while the MDi module is specifically designed to preserve a high feature resolution. Therefore, the network adeptly captures long-range dependencies, extracts high-level semantic content, and retains low-level detail information from tongue images. Moreover, it maintains decent precision and stable generalization capabilities, even when dealing with limited sample sizes. Experimental results show that the accuracy and generalization ability of GA-TongueNet in complex environments are significantly better than various existing semantic segmentation algorithms based on Convolutional Neural Networks (CNN) and Transformer architectures.