Frontiers in Physiology | New and Recent Articles https://www.frontiersin.org/journals/physiology RSS Feed for Frontiers in Physiology | New and Recent Articles en-us Frontiers Feed Generator,version:1 2026-08-22T18:40:36.907+00:00 60 https://www.frontiersin.org/articles/10.3389/fphys.2026.1911653 https://www.frontiersin.org/articles/10.3389/fphys.2026.1911653 <![CDATA[Photoacoustic imaging of acupoint specificity and meridian transmission at Shousanli (LI10): a blood oxygen metabolism study]]> 2026-08-21T00:00:00Z Original Research Cheng ZengYameng LiuLinping PianJingjing ZhaoLinying WangLiping PeiJiawei LiuXueyan GaoDanke MaJing Gao https://www.frontiersin.org/articles/10.3389/fphys.2026.1917944 https://www.frontiersin.org/articles/10.3389/fphys.2026.1917944 <![CDATA[The seminal plasma sTLR4/IL-1β ratio as an independent factor associated with sperm chromatin condensation defects]]> 2026-08-21T00:00:00Z Original Research Ying ZhaoZegeng LinLiangju ChenFangmei XieLin ZhongWenfeng LuoJinhua HeMingyi YeZeping Han 30%, n = 37) based on aniline blue staining. Seminal plasma levels of inflammatory markers, including HMGB1, sTLR4, IL-1β, TNF-α and oxidative stress markers, including 8-iso-PGF2α, total antioxidant capacity (T-AOC) were measured. Spearman correlation analysis, Firth’s penalized logistic regression, and receiver operating characteristic (ROC) curve analysis was employed to evaluate the discriminative performance of the biomarkers and the combined score, respectively.ResultsUnivariate Firth regression analysis revealed that the sTLR4/IL-1β ratio was a factor associated with reduced risk against SCCD (OR approaching 0, 95% CI: 0.00 - 0.04, P = 0.006), while T-AOC was significantly associated with increased risk of SCCD (OR = 200.99, 95% CI: 1.52 - 38205.02, P = 0.033). Multivariable analysis confirmed that sTLR4/IL-1β remained an independent factor associated with reduced SCCD risk after adjusting for confounders (P < 0.001), whereas T-AOC was not statistically significant in the multivariable model (P = 0.472). ROC curve analysis yielded an area under the curve (AUC) of 0.786 for sTLR4/IL-1β, indicating moderate-to-good discriminative ability.ConclusionA higher seminal plasma sTLR4/IL-1β ratio is independently associated with reduced SCCD risk, suggesting that preserved immunological buffering may protect sperm chromatin integrity. The sTLR4/IL-1β ratio demonstrates moderate-to-good discriminatory ability (AUC = 0.786) and, as an exploratory finding, may serve as a potential auxiliary assessment tool in future larger validation studies.]]> https://www.frontiersin.org/articles/10.3389/fphys.2026.1912788 https://www.frontiersin.org/articles/10.3389/fphys.2026.1912788 <![CDATA[Divergent intestinal barrier and neuroimmune responses to supervised exercise across fibromyalgia, irritable bowel syndrome, and their comorbidity phenotypes: a prospective interventional study]]> 2026-08-21T00:00:00Z Original Research Antonella BiancoFrancesco RussoLaura ProsperoGaetana LaselvaMarco GrassoBenedetta D’AttomaNicola VerrelliAntonia IgnazziIsabella FrancoElisa GrazioliAttilio ParisiGiuseppe Riezzo https://www.frontiersin.org/articles/10.3389/fphys.2026.1909505 https://www.frontiersin.org/articles/10.3389/fphys.2026.1909505 <![CDATA[Feasibility of heart rate monitoring in hemodialysis patients using visible imaging: a pilot study]]> 2026-08-20T00:00:00Z Brief Research Report Uday DebnathSreya Deb SresthaSungho Kim https://www.frontiersin.org/articles/10.3389/fphys.2026.1817927 https://www.frontiersin.org/articles/10.3389/fphys.2026.1817927 <![CDATA[Integrating reflex, feedback, and prediction: a tiered model of physiological regulation for contemporary medical education]]> 2026-08-20T00:00:00Z Hypothesis and Theory Changiz MohiyeddiniSuzan Kamel-ElSayed https://www.frontiersin.org/articles/10.3389/fphys.2026.1930628 https://www.frontiersin.org/articles/10.3389/fphys.2026.1930628 <![CDATA[Gastrointestinal motility in microgravity: a critical review of multi-level mechanisms and model-dependent effects]]> 2026-08-20T00:00:00Z Review Qian NiuTong MuJunhai ZhangYue ChenZhikun GuoYuanmin ZhuLin Li https://www.frontiersin.org/articles/10.3389/fphys.2026.1926017 https://www.frontiersin.org/articles/10.3389/fphys.2026.1926017 <![CDATA[Effects of 8-week polarized vs. threshold training on cardiorespiratory fitness, post-exercise heart-rate recovery, and target accuracy under fatigue in table tennis players]]> 2026-08-19T00:00:00Z Original Research Wenyuan WangYushan HeEnli Xie https://www.frontiersin.org/articles/10.3389/fphys.2026.1924373 https://www.frontiersin.org/articles/10.3389/fphys.2026.1924373 <![CDATA[From single-pathway cascade to network pathophysiology: how genetically engineered mouse models reshaped our understanding of pancreatitis]]> 2026-08-19T00:00:00Z Review Ting YanQinghua LinShaoqun HuangLingxiang Wang https://www.frontiersin.org/articles/10.3389/fphys.2026.1907835 https://www.frontiersin.org/articles/10.3389/fphys.2026.1907835 <![CDATA[Characterization of calcium sources and downstream signaling pathways following electrical field stimulation of rodent longitudinal esophageal muscle]]> 2026-08-19T00:00:00Z Original Research Michelle GräfeJulius-Neven KrieseTimo KirschsteinRüdiger KöhlingFelix BockFelix SchulzeGuido HildebrandtBernd Frerker https://www.frontiersin.org/articles/10.3389/fphys.2026.1835199 https://www.frontiersin.org/articles/10.3389/fphys.2026.1835199 <![CDATA[Serum calcium-magnesium-phosphate-potassium metabolic dysregulation in nephrolithiasis: predictive model development and mechanistic insights]]> 2026-08-19T00:00:00Z Original Research Yunhan WangCaitao DongWenbiao LiaoSixing Yang https://www.frontiersin.org/articles/10.3389/fphys.2026.1916986 https://www.frontiersin.org/articles/10.3389/fphys.2026.1916986 <![CDATA[Time-dependent changes in aerobic capacity of acute sub-high altitude exposure in elite youth endurance athletes]]> 2026-08-19T00:00:00Z Original Research Junpeng FengFengming NingXuchang ZhangYe TaoMingyue SunWenqiang Wu https://www.frontiersin.org/articles/10.3389/fphys.2026.1810924 https://www.frontiersin.org/articles/10.3389/fphys.2026.1810924 <![CDATA[Does kidney function in experimental porcine sepsis fulfill the RIFLE criteria for acute kidney injury? A systematic review]]> 2026-08-19T00:00:00Z Systematic Review Kjellbjørn JakobsenViktoria Instanes MarkussenHendrik Joachim BackmannEirik ReierthAnders Benjamin KildalLars Marius Ytrebø https://www.frontiersin.org/articles/10.3389/fphys.2026.1928397 https://www.frontiersin.org/articles/10.3389/fphys.2026.1928397 <![CDATA[Decoding vascular calcification-neutrophil signature in pathogenesis of chronic IgA nephropathy: evidence from artificial intelligence-driven multi-omics and in vitro validation]]> 2026-08-19T00:00:00Z Original Research Chunyu CaoWencheng YanMingyue LiJing Lu https://www.frontiersin.org/articles/10.3389/fphys.2026.1907874 https://www.frontiersin.org/articles/10.3389/fphys.2026.1907874 <![CDATA[Extended secondhand smoke exposure alters potassium channel activity and reduces excitability of cardiac vagal neurons in mice]]> 2026-08-19T00:00:00Z Original Research Junqing SunShiyue PanEmma KareyKent E. PinkertonChao-Yin Chen https://www.frontiersin.org/articles/10.3389/fphys.2026.1923189 https://www.frontiersin.org/articles/10.3389/fphys.2026.1923189 <![CDATA[Patient education for neuromyelitis optica spectrum disorder using large language models: combining expert assessment and real-world patient interaction]]> 2026-08-19T00:00:00Z Original Research Chen LiYuting HuXiaoyan WangRuoyi YaoJiahao YeShanshan DiaoYanhui XiaoYingming WangMingying LaiWeihua Yang https://www.frontiersin.org/articles/10.3389/fphys.2026.1911464 https://www.frontiersin.org/articles/10.3389/fphys.2026.1911464 <![CDATA[Exercise patterns and atherosclerosis: a network meta-analysis based on randomized controlled trials]]> 2026-08-18T00:00:00Z Systematic Review Cheng XuShuxin YanYuxin LiuHui ZhangFei LiYu ZhangYiying LiuYulian YuanShujing ZhangXianggen ZhongYan Sun https://www.frontiersin.org/articles/10.3389/fphys.2026.1885059 https://www.frontiersin.org/articles/10.3389/fphys.2026.1885059 <![CDATA[Effects of high-intensity interval training on cardiorespiratory fitness in adolescents with overweight or obesity: a systematic review and dose–response meta-analysis]]> 2026-08-18T00:00:00Z Systematic Review Jinchen PanXusong DongRuiqi ChengJianmei CuiWeian LinLei Zheng https://www.frontiersin.org/articles/10.3389/fphys.2026.1898182 https://www.frontiersin.org/articles/10.3389/fphys.2026.1898182 <![CDATA[Form informs function: innervation patterns of projection neurons correspond to response profiles of mushroom body output neurons during olfactory-visual integration]]> 2026-08-18T00:00:00Z Original Research Athil Althaf Aliyam Veetil ZyndheenAndrea Rafaela NicolaidouClaudia GrohVolker DürrWolfgang RösslerMartin Strube-Bloss https://www.frontiersin.org/articles/10.3389/fphys.2026.1828577 https://www.frontiersin.org/articles/10.3389/fphys.2026.1828577 <![CDATA[Membrane-decisional architecture: a framework for multigenomic signal prioritization in the plasma membrane nanobiome]]> 2026-08-18T00:00:00Z Review João Francisco Pollo GasparyLuis Felipe Dias LopesFernanda Peron GasparyCarmen Brum RosaEduarda Grando LopesAlfred Lee EdgarEduardo Poletti CamaraAntonio Geraldo Camara https://www.frontiersin.org/articles/10.3389/fphys.2026.1911093 https://www.frontiersin.org/articles/10.3389/fphys.2026.1911093 <![CDATA[Baseline cognitive performance moderates ACL injury–related knee biomechanics during unanticipated sidestep cutting in highly trained male soccer players]]> 2026-08-18T00:00:00Z Original Research Weipeng LiuZilong WangZhuangzhuang WangZhiyuan QinZhengwei WuWeihua ZhengCongjie ChengWeichao LiWenhua Li