Scope

Renal and Epithelial Physiology deals with all aspects of renal physiology ranging from molecular and cellular physiology of renal cells to translational research bringing renal research to the bedside. In addition, the Specialty will also consider papers on the fundamental properties of epithelial tissues that are not covered by other areas of physiology. We welcome original papers on a broad range of subjects relating to the kidney, urinary tract, and their respective cells and vasculature, as well as to the control of body fluid volume and composition. Contributions that use cellular and molecular approaches to shed light on the structure and function of epithelial cell membranes and membrane channels, transporters and pumps; and studies dealing with integrated regulation of epithelial cellular function, including mechanisms of signal transduction, development, gene expression and cell-to-cell interactions, are also encouraged. Studies may involve human or animal models, individual cell types, and isolated membrane systems. Authors are encouraged to submit reports on research using a wide range of approaches to the study of function in epithelial and renal systems, such as biochemistry, immunology, genetics, mathematical modeling, molecular biology and physiological methodologies. Papers on the pathophysiological basis of disease processes of epithelial tissues, the kidney, urinary tract and the regulation of body fluids are also encouraged.

Please consider the content and article type specifications as stated below 

Articles that address purely pathological processes or treatment/management of disease do not fall within the areas covered by Frontiers in Physiology. Articles of this type must be submitted to a more appropriate clinical journal. As an example, all cancer related articles should be submitted to an appropriate section of Frontiers in Oncology. Articles that focus exclusively on disease processes will be returned to authors without review, and/or with a suggestion to submit to a more appropriate Frontiers journal. Similarly, all articles with a research focus on genes and genomes should be submitted to an appropriate section of Frontiers in Genetics; these submissions will not be considered for review in Frontiers in Physiology.

Please note that not all Article Types are available in all Sections. Some article types, such as those that mention medicine, are section specific. Authors are encouraged to refer to the section specific 'About' pages for available article types. Special circumstances related to sections cross-listed between two or more journals also apply, read more below. Only article types that appear in the drop-down menu during the submission process are available for submission to the selected section.

Frontiers in Physiology no longer accepts Clinical Trials and Case Reports, including pilot studies.

The WHO defines a clinical trial as "any research study that prospectively assigns human participants or groups of humans to one or more health-related interventions to evaluate the effects on health outcomes". 

In most cases, these submissions should be directed to one of the Frontiers medically related journals. Articles of this nature submitted to Frontiers in Physiology will be returned to authors without review, and/or with a suggestion to submit to a more appropriate Frontiers journal.

Due to the nature of our publishing program, sections cross-listed between two or more journals (for e.g. Autonomic Neuroscience, Biophysics, Exercise Physiology, Medical Physics and Imaging, Reproduction) may continue to welcome these article types, and others, by submission through the other relevant field journal. However, authors should not proceed with submission of a clinical trial, case report or pilot study through Frontiers in Physiology. As stated, articles of this nature submitted to Frontiers in Physiology will be returned to authors without review, and/or with a suggestion to submit to a more appropriate Frontiers journal.

In the case of General Commentaries, the journal will only consider those which comment on a paper already published with Frontiers. Special exception may be given if a commentary addresses a body of knowledge, pending approval from section Chief Editors.

Submission

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