https://www.frontiersin.org/journals/physiology/sections/skeletal-physiology RSS Feed for Skeletal Physiology section in the Frontiers in Physiology journal | New and Recent Articles en-us Frontiers Feed Generator,version:1 2026-05-14T09:55:54.258+00:00 60 https://www.frontiersin.org/articles/10.3389/fphys.2026.1820186 https://www.frontiersin.org/articles/10.3389/fphys.2026.1820186 2026-05-14T00:00:00Z Original Research Xiaoteng LiFengzi LvXin TangPeng JiaYang Gao anterior height at L1 and L2, showed no statistically significant difference at L3, and anterior height > posterior height at L4 and L5. The cortical thickness of the anterior one-third of the superior endplate was significantly smaller according to the posterior one-third (P < 0.05). ② CT values: Within vertebral bodies, CT attenuation values showed a gradual increase from the upper one-third to the lower one-third regions. Comparison across segments roughly followed the pattern L1 > L2 > L5 > L3 > L4. Across all segments, the CT value in the anterosuperior region of the vertebral body (anterosuperior region) was the lowest.ConclusionThe morphology of lumbar vertebral bodies demonstrates a consistent morphological trend from L1 to L5 which may be associated with increasing axial loads and contribute to physiological lordosis. There is significant heterogeneity in the distribution of BMD within the vertebral body, with the anterosuperior region identified as a “stress-weak zone, ” highly consistent with the predilection site for clinical compression fractures. The morphological and densitometric database established in this study can provide reference data for spinal surgery planning, implant design, and biomechanical research.]]> https://www.frontiersin.org/articles/10.3389/fphys.2026.1821673 https://www.frontiersin.org/articles/10.3389/fphys.2026.1821673 2026-05-13T00:00:00Z Original Research Jorge Posada-OrdaxMarta Elena Losa-IglesiasRicardo Becerro de Bengoa-VallejoEduardo Pérez-BoalBibiana Trevissón-RedondoIsrael Casado-HernándezAntonio Javier Casanova-MalpicaEva María Martínez-JiménezHugo Espigares-MartínezFrancisco Javier Ruiz-Sánchez https://www.frontiersin.org/articles/10.3389/fphys.2026.1795836 https://www.frontiersin.org/articles/10.3389/fphys.2026.1795836 2026-05-05T00:00:00Z Original Research Weiwei XiangZhen LvXinwen MinJunhao ZhangHandong YangJun ChenJishun ChenDongfeng LiHao XuChao LuoWenwen Wu 0.05), between the two groups. Body weight monitoring revealed that the CSD group had significantly lower body weight at the early stage of the experiment (week 1) and at week 8 compared with the controls (P < 0.05). No significant differences were observed at most other time points, showing a fluctuating pattern with baseline differences.ConclusionThree months of CSD led to decreased BMD and trabecular thinning in middle-aged and older male mice. No significant deterioration of overall bone biomechanical properties was observed, suggesting the presence of compensatory mechanisms in bone. The effect of sleep deprivation on body weight was intermittent rather than sustained. These findings provide experimental evidence for a comprehensive understanding of the relationship between sleep duration and skeletal health.]]> https://www.frontiersin.org/articles/10.3389/fphys.2026.1809107 https://www.frontiersin.org/articles/10.3389/fphys.2026.1809107 2026-05-04T00:00:00Z Review Zhigang ChenZhiwei Niu https://www.frontiersin.org/articles/10.3389/fphys.2026.1794324 https://www.frontiersin.org/articles/10.3389/fphys.2026.1794324 2026-04-23T00:00:00Z Review Juan MengShu-qiong XuQi DengLing-ling JiangDan-Ping HuangQing-song WangYong-Kang Wu https://www.frontiersin.org/articles/10.3389/fphys.2026.1789642 https://www.frontiersin.org/articles/10.3389/fphys.2026.1789642 2026-04-17T00:00:00Z Review Kamal AwadJulia AguirreMisturat AdegbiteAkhilla Sajeev KumarAhmed S. YacoubMingxin XiaMarco Brotto https://www.frontiersin.org/articles/10.3389/fphys.2026.1769763 https://www.frontiersin.org/articles/10.3389/fphys.2026.1769763 2026-04-15T00:00:00Z Systematic Review Muhammad Hafiz Zuhdi FairofNorwahidah Abdul KarimTheng Choon OoiLeong Chen LewArimi Fitri Mat LudinNor Fadilah Rajab https://www.frontiersin.org/articles/10.3389/fphys.2026.1792752 https://www.frontiersin.org/articles/10.3389/fphys.2026.1792752 2026-04-10T00:00:00Z Review Qi ShuaiJun TianWenlong YangSanting Huang https://www.frontiersin.org/articles/10.3389/fphys.2026.1791427 https://www.frontiersin.org/articles/10.3389/fphys.2026.1791427 2026-03-24T00:00:00Z Original Research Shuang MaQi YaoXiaoxue BaoYukun Li https://www.frontiersin.org/articles/10.3389/fphys.2026.1816216 https://www.frontiersin.org/articles/10.3389/fphys.2026.1816216 2026-03-23T00:00:00Z Correction Zihan XuChao YangFeng WuXiaowen TanYaxiu GuoHongyu ZhangHailong WangXiukun SuiZi XuMinbo ZhaoSiyu JiangZhongquan DaiYinghui Li https://www.frontiersin.org/articles/10.3389/fphys.2026.1779440 https://www.frontiersin.org/articles/10.3389/fphys.2026.1779440 2026-03-16T00:00:00Z Original Research Caifeng WuYuanxin ChenYanshi LiuLian TangXiaoheng DingAihemaitijiang YusufuKai Liu https://www.frontiersin.org/articles/10.3389/fphys.2025.1726583 https://www.frontiersin.org/articles/10.3389/fphys.2025.1726583 2026-02-16T00:00:00Z Original Research Sandra DieterichChristoph KölblMiriam Eva Angelica Tschaffon-MüllerOliver KüppersDorothea GebauerMelanie Rebecca KuhnKatarina Teresa AckerAnita IgnatiusMelanie Haffner-Luntzer https://www.frontiersin.org/articles/10.3389/fphys.2026.1780014 https://www.frontiersin.org/articles/10.3389/fphys.2026.1780014 2026-02-11T00:00:00Z Original Research Xingxing ShenJiahao ChenJiahao ZhangJiaqing TianSirun ChengJichuan CaoCongcong LiXuemeng Xu https://www.frontiersin.org/articles/10.3389/fphys.2025.1737373 https://www.frontiersin.org/articles/10.3389/fphys.2025.1737373 2026-01-12T00:00:00Z Systematic Review Liang MaJia-Qiang LiuKun YuMei-Yun Tan 0.05). The overall risk of bias among the included studies was moderate, primarily due to unclear allocation concealment and lack of blinding.ConclusionCompared with traditional rehabilitation, mobile app–based digital rehabilitation after total knee arthroplasty was associated with improved pain relief and better performance-based functional outcomes, as well as greater early gains in knee range of motion. No significant difference was observed in composite knee function scores. Given the low to moderate certainty of evidence, app-based rehabilitation may be considered as an adjunct or alternative rehabilitation strategy for selected patients, while further high-quality randomized controlled trials are needed to confirm long-term effectiveness.]]> https://www.frontiersin.org/articles/10.3389/fphys.2025.1710819 https://www.frontiersin.org/articles/10.3389/fphys.2025.1710819 2025-12-02T00:00:00Z Original Research Xingxing ShenJiaqing TianJiahao ChenJiahao ZhangSirun ChengRuian XiangXuemeng Xu 0.05). Regarding the FPI asymmetry scores, the proportion of asymmetry (including asymmetry and severe asymmetry) in the UG (65.6%) was much more frequent compared with that of BG (34.3%), with a statistically significant difference (χ2 = 6.57, P = 0.01). Furthermore, the VAS score and K/L grade were significantly correlated with the FPI asymmetric score in the UG (b = 1.065; 95% CI: 0.194, 1.936; p = 0.019 and b = 1.770; 95% CI: 0.215, 3.325; p = 0.028, respectively) and BG (b = 0.665; 95% CI: 0.117, 1.212; p = 0.020 and b = 1.523; 95% CI: 0.414, 2.632; p = 0.009, respectively).ConclusionBoth unilateral and bilateral patients with KOA exhibited a propensity for asymmetry in the properties of the QF, RMS values, and foot postures on both sides. Notably, unilateral patients tended to demonstrate this asymmetry more prominently and exhibit a higher prevalence of foot posture asymmetry compared to those bilateral patients. Furthermore, the degree of foot posture asymmetry was closely linked to pain severity and K/L grading whether in unilateral or bilateral KOA patients.]]> https://www.frontiersin.org/articles/10.3389/fphys.2025.1717233 https://www.frontiersin.org/articles/10.3389/fphys.2025.1717233 2025-11-17T00:00:00Z Review Hongyi XuZihui GaoXinlei YaoJiacheng SunBingqian Chen https://www.frontiersin.org/articles/10.3389/fphys.2025.1664568 https://www.frontiersin.org/articles/10.3389/fphys.2025.1664568 2025-11-04T00:00:00Z Review Marco CaremaniIrene PerticiIlaria MorottiPasquale BiancoMassimo ReconditiGabriella PiazzesiVincenzo LombardiMarco Linari https://www.frontiersin.org/articles/10.3389/fphys.2025.1684102 https://www.frontiersin.org/articles/10.3389/fphys.2025.1684102 2025-11-03T00:00:00Z Original Research Faleh TamimiHazem EimarSharifa AlebrahimLina Abu-NadaGarthiga ManickamAhmed Ebraheem Al SubaieIskandar TamimiMonzur Murshed https://www.frontiersin.org/articles/10.3389/fphys.2025.1711795 https://www.frontiersin.org/articles/10.3389/fphys.2025.1711795 2025-10-30T00:00:00Z Perspective Jingjuan ChenMarco BrottoRadbod DarabiAshok Kumar https://www.frontiersin.org/articles/10.3389/fphys.2025.1685955 https://www.frontiersin.org/articles/10.3389/fphys.2025.1685955 2025-10-29T00:00:00Z Review Tingming PanZhong DongHongjie ZhangFengmin YangYating Chen