AUTHOR=Schubert Ingo , Schubert Veit , Fuchs Jörg TITLE=No Evidence for “Break-Induced Replication” in a Higher Plant – But Break-Induced Conversion May Occur JOURNAL=Frontiers in Plant Science VOLUME=Volume 2 - 2011 YEAR=2011 URL=https://www.frontiersin.org/journals/plant-science/articles/10.3389/fpls.2011.00008 DOI=10.3389/fpls.2011.00008 ISSN=1664-462X ABSTRACT=
“Break-induced replication” (BIR) is considered as one way to repair DNA double-strand breaks (DSBs). BIR is defined as replication of the proximal break-ends up to the end of the broken chromosome using an undamaged (homologous) double-stranded template and mimicking a non-reciprocal translocation. This phenomenon was detected by genetic experiments in yeast. BIR is assumed to occur also in mammals, but experimental evidence is not yet at hand. We have studied chromosomes of the field bean,