AUTHOR=Zhang Wen-Jing , Hanisch Susanne , Kwaaitaal Mark , Pedersen Carsten , Thordal-Christensen Hans TITLE=A component of the Sec61 ER protein transporting pore is required for plant susceptibility to powdery mildew JOURNAL=Frontiers in Plant Science VOLUME=Volume 4 - 2013 YEAR=2013 URL=https://www.frontiersin.org/journals/plant-science/articles/10.3389/fpls.2013.00127 DOI=10.3389/fpls.2013.00127 ISSN=1664-462X ABSTRACT=
Biotrophic pathogens, like the powdery mildew fungi, require living plant cells for their growth and reproduction. During infection, a specialized structure called the haustorium is formed by the fungus. The haustorium is surrounded by a plant cell-derived extrahaustorial membrane (EHM). Over the EHM, the fungus obtains nutrients from and secretes effector proteins into the plant cell. In the plant cell these effectors interfere with cellular processes such as pathogen defense and membrane trafficking. However, the mechanisms behind effector delivery are largely unknown. This paper provides a model for and new insights into a putative transfer mechanism of effectors into the plant cell. We show that silencing of the barley Sec61βa transcript results in decreased susceptibility to the powdery mildew fungus.