AUTHOR=Kondo Yuki , Tamaki Takayuki , Fukuda Hiroo TITLE=Regulation of xylem cell fate JOURNAL=Frontiers in Plant Science VOLUME=Volume 5 - 2014 YEAR=2014 URL=https://www.frontiersin.org/journals/plant-science/articles/10.3389/fpls.2014.00315 DOI=10.3389/fpls.2014.00315 ISSN=1664-462X ABSTRACT=The vascular system is deliberately placed throughout the plant body for transporting water, nutrients, and signaling molecules. During vascular development, xylem, phloem, and procambial/cambial cells are differentiated in a spatiotemporally organized manner. Up to now, various key regulators for xylem cell patterning and differentiation such as auxin, cytokinin, CLE peptides, microRNAs, HD-ZIPIIIs, VNDs, and moving transcription factors SHR and AHLs have been discovered. Recent studies are revealing functional interactions among such factors to eventually determine the xylem cell fate. This review focuses on networks of various regulators underlying xylem cell fate determination in root vascular development.