AUTHOR=Makai Szabolcs , Tamás László , Juhász Angéla TITLE=A Catalog of Regulatory Sequences for Trait Gene for the Genome Editing of Wheat JOURNAL=Frontiers in Plant Science VOLUME=Volume 7 - 2016 YEAR=2016 URL=https://www.frontiersin.org/journals/plant-science/articles/10.3389/fpls.2016.01504 DOI=10.3389/fpls.2016.01504 ISSN=1664-462X ABSTRACT=
Wheat has been cultivated for 10000 years and ever since the origin of hexaploid wheat it has been exempt from natural selection. Instead, it was under the constant selective pressure of human agriculture from harvest to sowing during every year, producing a vast array of varieties. Wheat has been adopted globally, accumulating variation for genes involved in yield traits, environmental adaptation and resistance. However, one small but important part of the wheat genome has hardly changed: the regulatory regions of both the x- and y-type high molecular weight glutenin subunit (HMW-GS) genes, which are alone responsible for approximately 12% of the grain protein content. The phylogeny of the HMW-GS regulatory regions of the