AUTHOR=Timmusk Salme , Behers Lawrence , Muthoni Julia , Muraya Anthony , Aronsson Anne-Charlotte TITLE=Perspectives and Challenges of Microbial Application for Crop Improvement JOURNAL=Frontiers in Plant Science VOLUME=Volume 8 - 2017 YEAR=2017 URL=https://www.frontiersin.org/journals/plant-science/articles/10.3389/fpls.2017.00049 DOI=10.3389/fpls.2017.00049 ISSN=1664-462X ABSTRACT=Global population increases and climate change pose a challenge to worldwide crop production. There is a need to intensify agricultural production in a sustainable manner and to find solutions to combat abiotic stress, pathogens and pests. Plants are associated with complex microbiomes, which are known to promote plant growth and stress tolerance, support plant nutrition and antagonize plant pathogens. The integration of beneficial plant-microbe and microbiome interactions may represent a promising sustainable solution to improve agricultural production. Commercial application of these microorganisms needs complex approaches, both in the technology in the field, and in marketing, extension education and ownership of the patent rights.