AUTHOR=Zhu Wenjun , Dong Huange , Xu Ran , You Jingmao , Yan Da-zhong , Xiong Chao , Wu Jing , Bi Kai 

TITLE=Botrytis cinerea BcCDI1 protein triggers both plant cell death and immune response

JOURNAL=Frontiers in Plant Science

VOLUME=14

YEAR=2023

URL=https://www.frontiersin.org/journals/plant-science/articles/10.3389/fpls.2023.1136463

DOI=10.3389/fpls.2023.1136463

ISSN=1664-462X

ABSTRACT=<p>Cell death-inducing proteins (CDIPs) play important roles in the infection of <italic>Botrytis cinerea</italic>, a broad host-range necrotrophic phytopathogen. Here, we show that the secreted protein BcCDI1 (Cell Death Inducing 1) can cause necrosis in tobacco leaves and at the same time elicit plant defense. The transcription of <italic>Bccdi1</italic> was induced at the infection stage. Deletion or overexpression of <italic>Bccdi1</italic> resulted in no notable change in disease lesion on bean, tobacco, and <italic>Arabidopsis</italic> leaves, indicating that <italic>Bccdi1</italic> has no effect on the final outcome of <italic>B. cinerea</italic> infection. Furthermore, the plant receptor-like kinases BAK1 and SOBIR1 are required to transduce the cell death-promoting signal induced by BcCDI1. These findings suggest that BcCDI1 is possibly recognized by plant receptors and then induces plant cell death.</p>