AUTHOR=Zeng Yunmin , Muhammad Abid , Wan Lingyun , Gao Chenlu , Zhao Pinyao , El-Sappah Ahmed H. 

TITLE=Epitranscriptomic modifications for enhancing abiotic stress resistance in plants

JOURNAL=Frontiers in Plant Science

VOLUME=Volume 16 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/plant-science/articles/10.3389/fpls.2025.1538664

DOI=10.3389/fpls.2025.1538664

ISSN=1664-462X

ABSTRACT=Climate change significantly impedes agricultural growth, development, and production. Plants adapt to environmental changes via the plasticity given by essential genes, which are regulated at the post-/transcriptional level. Gene regulation in plants is a complex process governed by various cellular entities, including transcription factors, epigenetic regulators, and non-coding RNAs. Successful studies have confirmed the function of epigenetic alterations such as DNA methylation/histone modification) in gene expression. In recent years, a highly specialized science known as “Epitranscriptomics” has emerged. Epitranscriptomics studies post-transcriptional RNA chemical alterations seen in all living organisms that alter RNA’s structural, functional, and biological properties. Our minireview interpreted about understanding the molecular pathways: RNA changes and stress-responsive gene regulation. Additionally, the interplay between epitranscriptomics and other regulatory levels has been addressed. In addition, we reviewed technical breakthroughs in epitranscriptomic research, including tools and techniques.