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The discipline of bioinformatics and computational biology sits at the interface between biology, the quantitative sciences (such as mathematics, statistics, computer science) and engineering, and spans levels of investigation from single genes to systems. Section Bioinformatics and Computational Biology aims to rapidly publish new methods, research findings, opinions, and hypothesis articles on all aspects of the discipline.
As bioinformatics and computational biology bridges data interpretation (e.g. in genomics, transcriptomics, and proteomics) and software development, the section welcomes Original Research and Methods articles describing new analytical approaches and code — which may be as brief as required for accurate presentation. Additionally, reviews of new approaches can be submitted as Technology Reports.
As is fitting in such a fast-moving, broad discipline, we also seek attempts to connect different sub-fields of bioinformatics, as well as those that examine the history of bioinformatics and computational biology.
Section Bioinformatics and Computational Biology particularly encourages the submission of papers that discuss
i) new or improved algorithms, software and online services dealing with all of the below;
ii) analysis of amino acid and nucleotide sequences and structures;
iii) analysis of large multidimensional numeric datasets, including gene-expression; gene and protein interaction data; metabolite and small molecule profiling; and more;
iv) quantitative analysis of biological images;
v) phylogenetic approaches to biological questions;
vi) computational analysis of evolution of all life forms;
vii) mathematical or statistical modeling of all of the above.
Indexed in: PubMed, PubMed Central, Scopus, Web of Science, Google Scholar, DOAJ, CrossRef, AGRICOLA
PMCID: all published articles receive a PMCID
Bioinformatics and Computational Biology welcomes submissions of the following article types: Book Review, Correction, Editorial, General Commentary, Hypothesis and Theory, Methods, Mini Review, Opinion, Original Research, Perspective, Protocols, Review, Specialty Grand Challenge, Systematic Review and Technology Report.
All manuscripts must be submitted directly to the section Bioinformatics and Computational Biology, where they are peer-reviewed by the Associate and Review Editors of the specialty section.
Articles published in the section Bioinformatics and Computational Biology will benefit from the Frontiers impact and tiering system after online publication. Authors of published original research with the highest impact, as judged democratically by the readers, will be invited by the Chief Editor to write a Frontiers Focused Review - a tier-climbing article. This is referred to as "democratic tiering". The author selection is based on article impact analytics of original research published in all Frontiers specialty journals and sections. Focused Reviews are centered on the original discovery, place it into a broader context, and aim to address the wider community across all of Genetics, Plant Science and Bioengineering and Biotechnology.