AUTHOR=Ridgeway Laura , Okoye Albert , McClelland Ian , Dhossche Dirk , Kutay Deniz , Loureiro Mario TITLE=Case Report: A Case of Pediatric Catatonia: Role of the Lorazepam Challenge Test JOURNAL=Frontiers in Psychiatry VOLUME=Volume 12 - 2021 YEAR=2021 URL=https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2021.637886 DOI=10.3389/fpsyt.2021.637886 ISSN=1664-0640 ABSTRACT=A case of a 12-year-old boy who developed catatonia is presented. He had no previous psychiatric history but has a family history of affective disorder. An extensive medical work-up was negative. Despite a negative lorazepam challenge test, lorazepam was titrated up to 24 mg per day with resolution of most catatonic symptoms. The case highlights an important point in the management of catatonia that may be a source of confusion, i.e., a positive lorazepam challenge test corroborates the diagnosis of catatonia, however, a negative lorazepam challenge test does not negate the diagnosis of catatonia and subsequent focused benzodiazepine treatment may still be effective.