AUTHOR=Yang Chao , Lin Xiaoxiao , Wang Xianteng , Liu Huanzhong , Huang Jinyu , Wang Shuai 

TITLE=The schizophrenia and gut microbiota: A bibliometric and visual analysis

JOURNAL=Frontiers in Psychiatry

VOLUME=Volume 13 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2022.1022472

DOI=10.3389/fpsyt.2022.1022472

ISSN=1664-0640

ABSTRACT=Abstract
Background: Many studies have explored the link between gut microbiota and schizophrenia. To date, there was no bibliometric analyses to summarize the gut microbiota and schizophrenia. We aimed to conduct a bibliometric study of gut microbiota and schizophrenia to determine the current status and frontiers in this field.
Methods The literature related to gut microbiota and schizophrenia was retrieved from the Web of Science Core Collection (WoSCC).  WoSCC literature analysis wire and VOSviewer 1.6.16 were used to conduct the analysis. 
Results: 162 publications were included in our study. A total of 873 authors, 355 organizations from 40 countries/regions and 95 journals contributed to this field. The leading authors were Timothy Dinan, John F Cryan, and Emily Severance. The leading institutions were the Johns Hopkins University, the University College Cork and the University of Toronto. The most productive countries were the USA, China and the Canada. The most productive journals were Schizophrenia Research, Progress in Neuro Psychopharmacology Biological Psychiatry and Frontiers in Psychiatry. The important keywords in clusters were gut microbiome, bipolar disorder, schizophrenia, antipsychotics, weight gain, metabolic syndrome. gut-brain axis, autism, depression, inflammation, and brain.  
Conclusions: The studies about schizophrenia and gut microbiota were limited, and the contribution was mainly from the USA. More studies are needed and the number of publications from other countries should be improved in the future. The main research hotspots in the schizophrenia and gut microbiota were the characteristics of the microbiota composition, gut-brain axis and immune mediators, and interventions. Publications about schizophrenia and gut microbiota will provide new directions to find out the pathogenesis and treatment for schizophrenia and the metabolic side effects induced by antipsychotics.