AUTHOR=Zhao Xuhao , Hu Ruofei , Wen Haoxuan , Xu Guohai , Pang Ting , He Xindi , Zhang Yaping , Zhang Ji , Chen Christopher , Wu Xifeng , Xu Xin 

TITLE=A voice recognition-based digital cognitive screener for dementia detection in the community: Development and validation study

JOURNAL=Frontiers in Psychiatry

VOLUME=Volume 13 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2022.899729

DOI=10.3389/fpsyt.2022.899729

ISSN=1664-0640

ABSTRACT=Introduction: To facilitate community-based dementia screening, we developed a voice recognition-based digital cognitive screener (digital cognitive screener, DCS). This proof-of-concept study aimed to investigate the reliability, validity as well as the feasibility of the DCS among community-dwelling older adults in China.
Methods: Eligible participants completed demographic, clinical, and the DCS. Diagnosis of mild cognitive impairment (MCI) and dementia was made based on the Montreal Cognitive Assessment (MoCA) (MCI: MoCA < 23, dementia: MoCA < 14). Time and venue for test administration were recorded and reported. Internal consistency, test-retest reliability and inter-rater reliability were examined. Receiver operating characteristic (ROC) analyses were conducted to examine the discriminate validity of the DCS in detecting MCI and dementia. 
Results: A total of 103 participants completed all investigations and were included in the analysis. Administration time of the DCS was between 5.1-7.3 minutes. No significant difference (p>0.05) in test scores or administration time was found between 2 assessment settings (polyclinic or community center). The DCS showed good internal consistency (Cronbach’s alpha=0.73), test-retest reliability (Pearson r=0.69, p<0.001) and inter-rater reliability (ICC=0.84). Area under the curves (AUCs) of the DCS were 0.95(0.90, 0.99) and 0.77(0.67, 086) for dementia and MCI detection, respectively. At the optimal cut-off(7/8), the DCS showed excellent sensitivity (100%) and good specificity (80%) for dementia detection. 
Conclusion: The DCS is a feasible, reliable and valid digital dementia screening tool for older adults. The applicability of the DCS in a larger-scale community-based screening stratified by age and education levels warrants further investigation.