<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD Journal Archiving and Interchange DTD v2.3 20070202//EN" "archivearticle.dtd">
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="systematic-review" dtd-version="2.3" xml:lang="EN">
<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">Front. Psychiatry</journal-id>
<journal-title>Frontiers in Psychiatry</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Front. Psychiatry</abbrev-journal-title>
<issn pub-type="epub">1664-0640</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.3389/fpsyt.2023.1217561</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Psychiatry</subject>
<subj-group>
<subject>Systematic Review</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group>
<article-title>Mandatory substance use treatment for justice-involved persons in Germany: a systematic review of reoffending, treatment and the recurrence of substance use outcomes</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Tomlin</surname>
<given-names>Jack</given-names>
</name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<uri xlink:href="https://loop.frontiersin.org/people/723330/overview"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Meise</surname>
<given-names>Esther</given-names>
</name>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Wegner</surname>
<given-names>Juliane</given-names>
</name>
<xref ref-type="aff" rid="aff3"><sup>3</sup></xref>
</contrib>
<contrib contrib-type="author" corresp="yes">
<name>
<surname>V&#x00F6;llm</surname>
<given-names>Birgit</given-names>
</name>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref>
<xref ref-type="corresp" rid="c001"><sup>&#x002A;</sup></xref>
<uri xlink:href="https://loop.frontiersin.org/people/492968/overview"/>
</contrib>
</contrib-group>
<aff id="aff1"><sup>1</sup><institution>School of Law and Criminology, University of Greenwich</institution>, <addr-line>London</addr-line>, <country>United Kingdom</country></aff>
<aff id="aff2"><sup>2</sup><institution>Department of Forensic Psychiatry, University Medicine</institution>, <addr-line>Rostock</addr-line>, <country>Germany</country></aff>
<aff id="aff3"><sup>3</sup><institution>Institut f&#x00FC;r Medienforschung, University of Rostock</institution>, <addr-line>Rostock</addr-line>, <country>Germany</country></aff>
<author-notes>
<fn fn-type="edited-by" id="fn0001">
<p>Edited by: Morten Hesse, Aarhus University, Denmark</p>
</fn>
<fn fn-type="edited-by" id="fn0002">
<p>Reviewed by: Domna Tsaklakidou, University General Hospital Attikon, Greece; Malin Hildebrand Karl&#x00E9;n, University of Gothenburg, Sweden</p>
</fn>
<corresp id="c001">&#x002A;Correspondence: Birgit V&#x00F6;llm, <email>birgit.voellm@med.uni-rostock.de</email></corresp>
</author-notes>
<pub-date pub-type="epub">
<day>05</day>
<month>02</month>
<year>2024</year>
</pub-date>
<pub-date pub-type="collection">
<year>2023</year>
</pub-date>
<volume>14</volume>
<elocation-id>1217561</elocation-id>
<history>
<date date-type="received">
<day>05</day>
<month>05</month>
<year>2023</year>
</date>
<date date-type="accepted">
<day>21</day>
<month>12</month>
<year>2023</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright &#x00A9; 2024 Tomlin, Meise, Wegner and V&#x00F6;llm.</copyright-statement>
<copyright-year>2024</copyright-year>
<copyright-holder>Tomlin, Meise, Wegner and V&#x00F6;llm</copyright-holder>
<license xlink:href="http://creativecommons.org/licenses/by/4.0/">
<p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</p>
</license>
</permissions>
<abstract>
<p>Many jurisdictions implement mandatory substance use treatment for justice-involved persons. Germany is one such country; however, debates about the appropriateness and effectiveness of this disposal abound. Very little attention has been paid in the international literature to patients receiving mandatory treatment in Germany. This systematic review synthesises research on patients receiving substance use treatment in forensic hospitals under &#x00A7;64 of the German Penal Code with regard to three primary outcomes: treatment completion, reoffending, and the recurrence of substance use. Forty-five publications reporting on 36 studies were reviewed; publication dates ranged from 1988 to 2023. On average, 47% of patients did not successfully complete treatment, compared to 45% who did. Average follow-up reconviction rates were higher than in mentally ill and general offender populations as reported elsewhere. Approximately half of all patients reused substances during treatment. Suggestions for future research, including a focus on strength- and recovery-based indicators, and harmonising routine outcomes measurements, are given.</p>
</abstract>
<kwd-group>
<kwd>forensic mental health</kwd>
<kwd>substance use disorder</kwd>
<kwd>mandatory treatment</kwd>
<kwd>Germany</kwd>
<kwd>reoffending</kwd>
</kwd-group>
<counts>
<fig-count count="1"/>
<table-count count="5"/>
<equation-count count="0"/>
<ref-count count="82"/>
<page-count count="12"/>
<word-count count="10330"/>
</counts>
<custom-meta-wrap>
<custom-meta>
<meta-name>section-at-acceptance</meta-name>
<meta-value>Forensic Psychiatry</meta-value>
</custom-meta>
</custom-meta-wrap>
</article-meta>
</front>
<body>
<sec sec-type="intro" id="sec1">
<label>1</label>
<title>Introduction</title>
<sec id="sec2">
<label>1.1</label>
<title>Substance use and treatment in the criminal justice system</title>
<p>Substance misuse is strongly linked to criminal behaviour (<xref ref-type="bibr" rid="ref1">1</xref>). This association is described as a &#x2018;dynamic relationship&#x2019;, as the literature recognises that the links between drug-use and criminal behaviour are multi-directional (<xref ref-type="bibr" rid="ref2">2</xref>, <xref ref-type="bibr" rid="ref3">3</xref>). A history of substance misuse has been identified in the literature as a strong predictor of violence and recidivism in both the general offender population (<xref ref-type="bibr" rid="ref4">4</xref>) and for offenders with mental health disorders (<xref ref-type="bibr" rid="ref5">5</xref>, <xref ref-type="bibr" rid="ref6">6</xref>). In a systematic review of 18,388 newly admitted inmates across 24 studies, the authors found that approximately 30% of men and 51% of women had a drug misuse disorder, and a quarter of both sexes had an alcohol misuse disorder (<xref ref-type="bibr" rid="ref7">7</xref>).</p>
<p>Given the prevalence of substance use disorders in the criminal justice settings (CJS), various efforts aim to treat or divert people with substance use disorders away from traditional criminal justice disposals (<xref ref-type="bibr" rid="ref8">8</xref>). Alternative approaches include the use of drug courts, diversion schemes, mandatory or voluntary treatment programmes, pharmacological and psychosocial interventions, provided across a range of settings including secure hospitals, prisons, and various forms of support or monitoring in the community (<xref ref-type="bibr" rid="ref1">1</xref>). A comprehensive meta-analysis of 28 studies by Holloway et al. (<xref ref-type="bibr" rid="ref9">9</xref>) concluded that the likelihood of reoffending by individuals assigned to some form of treatment was 41% lower than controls not receiving such an intervention.</p>
<p>Evidence as to the effectiveness of different types of interventions is mixed (<xref ref-type="bibr" rid="ref1">1</xref>). For instance, although some studies suggest that for non-substance abusing offenders, community sentences lead to lower reoffending rates than penal sentences (<xref ref-type="bibr" rid="ref3">3</xref>), interventions targeting offenders with substance use disorders in the community are less effective than intensive programmes in secure environments (<xref ref-type="bibr" rid="ref9">9</xref>). Research indicates that programmes combining pharmacological and psychosocial elements are more effective than either delivered individually, and that therapeutic communities, which embody a secure holistic treatment approach, receive the most empirical support (<xref ref-type="bibr" rid="ref1">1</xref>). A review of 43 trials using non-pharmacological interventions for criminal justice-involved persons found that on average these led to a significant reduction in re-incarceration and a near significant reduction in substance use, but not in re-arrests; therapeutic communities were the only modality that led to significant reductions in re-arrests (<xref ref-type="bibr" rid="ref10">10</xref>). Further, interventions are differentially effective; non-white, young men are more likely to benefit than other groups (<xref ref-type="bibr" rid="ref9">9</xref>).</p>
</sec>
<sec id="sec3">
<label>1.2</label>
<title>Mandatory treatment and quasi-compulsory treatment</title>
<p>Mandatory treatment is defined as <italic>&#x2018;any form of drug treatment that is ordered, motivated, or supervised by the criminal justice system&#x2019;</italic> [(<xref ref-type="bibr" rid="ref11">11</xref>), 2]. In Germany, Austria and Switzerland, treatment can be ordered without requiring an individual&#x2019;s consent.</p>
<p>The evidence is mixed on the question of whether legal compulsion as compared to voluntary programmes is associated with better outcomes (<xref ref-type="bibr" rid="ref12">12</xref>). A review of the effectiveness of mandatory treatment interventions for people with substance use disorders found nine relevant studies (<xref ref-type="bibr" rid="ref13">13</xref>). Of these, three studies reported no difference between mandatory treatment and controls on substance use outcomes, two studies found &#x2018;equivocal&#x2019; links to positive substance use outcomes but there were no control groups, two studies reported positive outcomes, and two studies observed negative impacts on criminal recidivism (i.e., higher reoffending rates).</p>
<p>One of the reasons for heterogeneity in outcomes is the wide variation in programme intensity, modality, setting, and patient population. A review of coerced treatment programmes for substance using offenders identified programme- and individual-level factors that were associated with more successful outcomes (<xref ref-type="bibr" rid="ref14">14</xref>). At the programme-level, these included, among other things, programmes that: lasted longer than 90&#x2009;days, had compliance measures to enforce requirements, incorporated motivation and reinforcement techniques, ensured a continuum of care across the criminal justice system, and employed staff who had accreditation and training. At the individual-level, the authors report that greater motivation, treatment readiness, higher levels of religion and faith, and lower baseline stress levels were associated with better substance use and offending outcomes. Co-occurring mental disorders were linked with higher recidivism rates, and criminal thinking styles with poor engagement in treatment.</p>
</sec>
<sec id="sec4">
<label>1.3</label>
<title>Mandatory treatment for offenders with substance use disorders in Germany</title>
<p>The German criminal justice system provides for a form of mandatory treatment for offenders whose convictions are considered by a court to relate to substance use. &#x00A7;64 of the German Penal Code (Strafsgesetzbuch; StGB) stipulates that where an offence can be linked to a substance use disorder or is committed in a state of intoxication, there is risk of future substance use-related offending, and there are reasonable prospects that treatment might be successful, an individual can be ordered into a forensic mental health hospital specialising in the treatment of substance use disorders. These hospitals are secure forensic-psychiatric settings, the vast majority of which have secure perimeters. Some such hospitals specialise in treating individuals detained under &#x00A7;64 StGB while others also treat offender patients with other disorders having been committed under a hospital order with unlimited duration by the courts. There is no distinction of hospitals by security levels in Germany. The vast majority of forensic-psychiatric hospitals offer care at all levels of security but differentiate security levels internally within the same institution. Treatment models vary across these sites, though typically multidisciplinary, holistic treatment programmes involving a range of psychological, social, occupational, pharmacological, and substitution treatments are offered (<xref ref-type="bibr" rid="ref15">15</xref>).</p>
<p>The use of &#x00A7;64 StGB is independent of criminal responsibility; in practice about 60% of the individuals detained have full, and most of the remainder diminished, criminal responsibility. Both these groups receive a parallel prison sentence and could be returned to prison to serve this sentence if treatment does not appear to be successful. Detention under &#x00A7;64 StGB is ordered for a period of 2&#x2009;years, but can be extended by up to 2/3 of the length of the prison sentence ordered in parallel (<xref ref-type="bibr" rid="ref16">16</xref>). In case of long prison sentences, individuals will be ordered to serve part of the prison sentence prior to mandatory treatment in order to avoid them having to return to prison after successful completion of the treatment (<xref ref-type="bibr" rid="ref15">15</xref>). Placement is reviewed every 6&#x2009;months. As is common internationally, most patients are men (87.9%); the average age is 37&#x2009;years (<xref ref-type="bibr" rid="ref17">17</xref>, <xref ref-type="bibr" rid="ref18">18</xref>). Average treatment length is 3.5&#x2009;years (<xref ref-type="bibr" rid="ref15">15</xref>). There were 4,300 &#x00A7;64 German Penal Code patients in Germany in 2019, a marked increase from 1,657 in 1999 (<xref ref-type="bibr" rid="ref18">18</xref>). The reasons for this increase are not fully understood. However, a number of factors have been identified accounting for this observation: 1. There has been an increase in the average lengths of parallel prison sentences (by 9&#x2009;months over a period of 20&#x2009;years) due to an increase in severe (violent) offences. 2. As a consequence, average duration of treatment has also increased (by 6&#x2009;months). 3. The characteristics of patients have changed, in particular, the percentage of patients admitted with full criminal responsibility has increased due to a wider interpretation of the entry criteria by the courts. This has led some to argue that there are fewer ill and a greater number of dissocial patients with limited treatment motivation and poor prognosis now residing in forensic psychiatric care. Some have suggested that the possibility of early release provides a false incentive for this group (for a summary of the discussions see Bundesministerium f&#x00FC;r Justiz, 2022).</p>
<p>Approximately half of all patients do not successfully complete treatment (<xref ref-type="bibr" rid="ref15">15</xref>). This has raised questions about whether the right individuals are being selected for mandatory treatment in the first instance and led to calls, including from the German Association for Psychiatry, Psychotherapy and Psychosomatics (DGPPN), to significantly reform the admission criteria for treatment under this legal provision, including making such treatment voluntary (<xref ref-type="bibr" rid="ref19">19</xref>).</p>
<p>Knowledge of the outcomes for the &#x00A7;64 German Penal Code treatment population and the factors predictive or associated with these outcomes in the international (English language) literature is sparse. A recent study found that patients successfully completing treatment took significantly longer to reoffend (<italic>N</italic>&#x2009;=&#x2009;110, <italic>M</italic>&#x2009;=&#x2009;46&#x2009;months) than those transferred to prison (<italic>N</italic>&#x2009;=&#x2009;151, <italic>M</italic> =&#x2009;25&#x2009;months) (<xref ref-type="bibr" rid="ref20">20</xref>). A review by Fries et al. (<xref ref-type="bibr" rid="ref21">21</xref>) of nine papers published between 1999 and 2009 in German reported that young age, history of offending, lack of educational and vocational attainment, and comorbid personality disorders were the most robust predictors of treatment completion. A more recent review of 16 studies published after 1999 in German looking at predictors of treatment completion found that age, past criminal convictions, comorbid personality disorders, use of substances other than alcohol, educational and vocational attainment, withdrawal from previous substitution programmes, and needs mostly identified as substance-related instead of criminogenic, are the strongest predictors (<xref ref-type="bibr" rid="ref22">22</xref>). A second review conducted at the same time by the same authors address predictors of reoffending after discharge (<xref ref-type="bibr" rid="ref23">23</xref>). The authors report mixed findings but suggest that patient motivation, living circumstances and resources, and offending history were the most reliable predictors.</p>
</sec>
<sec id="sec5">
<label>1.4</label>
<title>Aims and rationale</title>
<p>The present review aimed to synthesise the literature describing studies of the mandatory substance use treatment patient population in Germany (&#x00A7;64 StGB) in relation to three primary outcomes: reconviction/reoffending, treatment completion and the recurrence of substance use. It summarises the reported prevalence rates for these outcomes and describes the evidence-base for factors/predictor variables associated with these outcomes. This review extends the findings of the previous reviews by additionally reporting on reconviction/reoffending during treatment and the recurrence of substance use during treatment and after discharge. It also is the first English-language review of this literature. The German system is worthy of study as the largest European jurisdiction to have mandatory substance use treatment, is currently reviewing laws relating to this, and little has been published on this system in the international literature.</p>
</sec>
</sec>
<sec sec-type="materials|methods" id="sec6">
<label>2</label>
<title>Materials and methods</title>
<p>The review protocol was published on PROSPERO [CRD42020148726]. The following search terms were used: [(psych&#x002A; or mental&#x002A;) AND (forensic&#x002A; or secur&#x002A; or crime&#x002A; or criminal&#x002A; or offend&#x002A; or offence&#x002A; or arrest&#x002A; or prisoner&#x002A; or inmate&#x002A; or incarcerate&#x002A; or quasi-compulsory or qct) AND (substance&#x002A; or drug&#x002A; or alcohol&#x002A; or misuse&#x002A; or addict&#x002A;) AND (outcome&#x002A; or predict&#x002A; or associate&#x002A;)]. The following databases were included in the review: PubMed; Web of Science; Embase; PsycINFO; MEDLINE; Cochrane Library; Google scholar (first 10 pages); Google search (first 10 pages); and the references of included articles were scanned to identify any further studies.</p>
<p>The following search parameters were set: the time limit included all records available for each database. Articles in English and German were included. Only studies of German services were included. An initial search was conducted in October 2019 and an updated search was conducted in November 2023.</p>
<sec id="sec7">
<label>2.1</label>
<title>PICOS and inclusion criteria</title>
<sec id="sec8">
<label>2.1.1</label>
<title>Population</title>
<p>In-patients in forensic psychiatric care settings that have a primary diagnosis of substance or alcohol misuse and have been mandated treatment for this in Germany under &#x00A7;64 StGB. Individuals found to have committed an offence with full, partial, or absent responsibility were included. Both male and female patients over 18&#x2009;years old were included. Patients that were released from forensic settings into the community or other services (general psychiatric, penal settings, out-patient settings) were included for follow-up (outcome) data.</p>
</sec>
<sec id="sec9">
<label>2.1.2</label>
<title>Intervention</title>
<p>Placement within a secure forensic setting under &#x00A7;64 StGB for the purposes of receiving treatment for substance or alcohol use diagnosis (not as a secondary diagnosis). People in jail/prison who happen to also receive an intervention for substance misuse were not included.</p>
</sec>
<sec id="sec10">
<label>2.1.3</label>
<title>Comparison</title>
<p>Not applicable.</p>
</sec>
<sec id="sec11">
<label>2.1.4</label>
<title>Outcomes</title>
<p>Primary outcomes were treatment completion, reoffending, and the recurrence of substance use. To support comparison of findings across studies, we defined <italic>successful treatment</italic> as: patients discharged into probation and those who reached the end of the legally-defined maximum length of treatment and were discharged; <italic>unsuccessful treatment</italic> included those patients for whom study authors reported there was &#x2018;treatment failure&#x2019;, were transferred to prison, or treatment was for another reason ended prematurely; and <italic>other outcomes</italic> as death or still being in treatment at time of data collection.</p>
<p><italic>Reoffending</italic> was defined as (1) officially recorded reconvictions in the &#x2018;Bundeszentralregister&#x2019; (Federal Central Register) after discharge from treatment, (2) officially recorded reconvictions in the Federal Central Register during treatment, (3) self-reported reoffending after treatment discharge, and (4) self-reported reoffending during treatment. Findings are described by category. Types of reoffences/reconvictions are not discussed in-depth as most studies reported any type of offending and did not investigate offence types (e.g., violent, sexual, property).</p>
<p>The <italic>recurrence of substance use</italic> is defined as any official, hospital, or self-reported record of substance use (illicit or licit, excluding caffeine and nicotine) in the study observation period. Very few studies distinguished between types of substances to a level of specificity greater than &#x2018;alcohol&#x2019; or &#x2018;other illicit substances&#x2019;. Therefore, the recurrence of substance use is not reported according to type of substance unless where the distinction between &#x2018;alcohol&#x2019; or &#x2018;other illicit substances&#x2019; is made explicit by study authors. Total number of recurrences can include more than one type of substance. We distinguish between substance relapse during and after treatment.</p>
<p>Predictors of these outcomes include but are not limited to demographic characteristics, historical characteristics such as history of offending, previous hospitalizations and history of substance use, and behavioural characteristics: treatment engagement, incidents of aggression in care, etc.</p>
</sec>
<sec id="sec12">
<label>2.1.5</label>
<title>Study designs</title>
<p>The following study designs were included: experimental studies such as randomised controlled trials and non-randomised controlled studies; non-experimental studies such as cohort studies, cross-sectional studies and case-studies. The following article types were included: peer reviewed articles, doctoral dissertations, and book chapters reporting empirical data. The following articles were excluded: introductions to special editions, book reviews, obituaries and literature reviews (primary sources were sought).</p>
</sec>
</sec>
<sec id="sec13">
<label>2.2</label>
<title>Data extraction and study selection</title>
<p>Key study data were extracted and recorded in a spreadsheet. These data include: authors, location of study, journal, year, type of study design, participants, description of secure setting (e.g., level of security), sample size, type of intervention if any, outcome variables, predictor variables, method of data analysis and the study findings. Data were extracted by JT, EM, PW and JW.</p>
<p>Our initial search returned 17,769 results (see PRISMA flow diagram in <xref ref-type="fig" rid="fig1">Figure 1</xref>); 5,572 results were removed after de-duplication. The titles and abstracts of 12,197 results were screened, with 11,971 removed; 226 results were sought for retrieval; 16 of these could not be found due to lack of access (authors were contacted where contact details were available). The results of 210 publications were assessed for eligibility and 192 of these were excluded in line with the review inclusion and exclusion criteria, leaving 18 hits. The reference lists of these 18 remaining papers were screened and 245 possible additional results were identified, 71 of these could not be accessed due to lack of access. Of these additional results, 174 were assessed for eligibility, of which 152 were excluded according to the review inclusion and exclusion criteria, leaving 23 hits. This left a total of 40 publications reporting on 32 studies. An updated search returned 23 possible hits for full text screening after deduplication. Five of these additional papers were added following eligibility screening.</p>
<fig position="float" id="fig1">
<label>Figure 1</label>
<caption>
<p>PRISMA flow diagram for initial search (updated search reported in section 2.2).</p>
</caption>
<graphic xlink:href="fpsyt-14-1217561-g001.tif"/>
</fig>
<p>Publications included in the review are indicated with an asterisk (&#x002A;) in the reference list.</p>
<p>Most publications reported on studies with cohort designs, of which 13 were retrospective and 21 prospective; there were six publications reporting cross-sectional studies; two retrospective case-controlled studies; and one case study. Sample sizes ranged from <italic>N</italic>&#x2009;=&#x2009;2 (<xref ref-type="bibr" rid="ref24">24</xref>) to <italic>N</italic>&#x2009;=&#x2009;2,483 (<xref ref-type="bibr" rid="ref25">25</xref>). Date of publication ranged from 1988 to 2023. There was a clear increase in the quality of reporting in the later studies rendering data extraction in more recent publications much easier. Five publications were in the English language, the rest in German.</p>
</sec>
<sec id="sec14">
<label>2.3</label>
<title>Data synthesis</title>
<p>Meta-analysis would not have produced meaningful insights given the number of variables measured in the literature and heterogeneous operationalisations [for example, number of past criminal offences was variously measured as: low, medium, and high severity in Gericke and Kallert (<xref ref-type="bibr" rid="ref26">26</xref>); total number of officially recorded convictions in, for example, Quereng&#x00E4;sser et al. (<xref ref-type="bibr" rid="ref27">27</xref>); and number of self-reported offences in Butz (<xref ref-type="bibr" rid="ref28">28</xref>)]. Therefore, we have chosen to present the findings as a narrative synthesis in line with the general framework proposed by the Centre for Reviews and Dissemination (<xref ref-type="bibr" rid="ref29">29</xref>). We do not articulate a theory of change as the treatment programmes, settings, and organisational cultures of the different forensic psychiatric hospitals that deliver mandatory treatment for this population over the studied time period vary widely. We develop a preliminary synthesis in the tables and text presented in our results section. We explore the relationships between studies by commenting on whether studies that investigate relationships between the same or similar variables draw convergent or divergent conclusions. We finally assess the robustness of our synthesis in the discussion section.</p>
<p>To strengthen the findings of the review, the sections below are a synthesis of findings relating to predictors that were investigated in more than one study. Significant and non-significant findings are reported. We present the findings relating to each primary outcome thematically (with the exception of the recurrence of substance use, for which there were fewer studies, and we present these findings in one section): legal and criminological; treatment and mental health; and social and demographic categories. Median values were the preferred measure of central tendency given the heterogeneity in outcome variables such as sample sizes and follow-up periods. Only publications reporting on studies using a cohort or cross-sectional design are included in the summary tables to increase the generalisability of findings. Case studies or studies of interventions are not included in these tables or used to contribute to median primary outcome values (e.g., reconviction rates); the findings from these studies are included in the textual description of results.</p>
</sec>
</sec>
<sec sec-type="results" id="sec15">
<label>3</label>
<title>Results</title>
<sec id="sec16">
<label>3.1</label>
<title>Reconviction/reoffending</title>
<sec id="sec17">
<label>3.1.1</label>
<title>Summary</title>
<p>Seven studies reported <italic>reconviction rates after discharge</italic>. <xref ref-type="table" rid="tab1">Table 1</xref> shows the number of patients who were reconvicted for an offence during a median follow-up of 30&#x2009;months. Median and interquartile range values are reported for these officially recorded offences. The median reconviction rate was 41% over these follow-up periods. Seven studies reported <italic>reoffending rates after discharge</italic>. Four studies reported <italic>reoffending during treatment</italic>; see <xref ref-type="table" rid="tab2">Table 2</xref>. Follow-up periods, definitions of recidivism, and sample sizes varied substantially across studies.</p>
<table-wrap position="float" id="tab1">
<label>Table 1</label>
<caption>
<p>Rates of reoffending/reconviction after discharge.</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="center" valign="top" colspan="4">Reconviction after discharge</th>
</tr>
<tr>
<th align="left" valign="top">Study</th>
<th align="center" valign="top">Reconviction %</th>
<th align="left" valign="top">Follow-up length</th>
<th align="center" valign="top">Sample size N</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="top">Koch (<xref ref-type="bibr" rid="ref30">30</xref>)</td>
<td align="center" valign="top">70%</td>
<td align="left" valign="top">Average 30&#x2009;months</td>
<td align="center" valign="top">63</td>
</tr>
<tr>
<td align="left" valign="top">Dessecker (<xref ref-type="bibr" rid="ref31">31</xref>)</td>
<td align="center" valign="top">41%</td>
<td align="left" valign="top">24&#x2009;months</td>
<td align="center" valign="top">249</td>
</tr>
<tr>
<td align="left" valign="top">Gericke and Kallert (<xref ref-type="bibr" rid="ref26">26</xref>)</td>
<td align="center" valign="top">36.7%</td>
<td align="left" valign="top">24&#x2009;months</td>
<td align="center" valign="top">120</td>
</tr>
<tr>
<td align="left" valign="top">Bezzel (<xref ref-type="bibr" rid="ref32">32</xref>)</td>
<td align="center" valign="top">35.4%</td>
<td align="left" valign="top">12&#x2009;months</td>
<td align="center" valign="top">173</td>
</tr>
<tr>
<td align="left" valign="top">Passow et al. (<xref ref-type="bibr" rid="ref33">33</xref>)</td>
<td align="center" valign="top">42.86%</td>
<td align="left" valign="top">36&#x2013;48&#x2009;months</td>
<td align="center" valign="top">84</td>
</tr>
<tr>
<td align="left" valign="top">Butz (<xref ref-type="bibr" rid="ref28">28</xref>)</td>
<td align="center" valign="top">25.1%</td>
<td align="left" valign="top">Average 40.2&#x2009;months</td>
<td align="center" valign="top">251</td>
</tr>
<tr>
<td align="left" valign="top">Quereng&#x00E4;sser et al. (<xref ref-type="bibr" rid="ref27">27</xref>)</td>
<td align="center" valign="top">66%</td>
<td align="left" valign="top">36&#x2009;months</td>
<td align="center" valign="top">261</td>
</tr>
<tr>
<td align="left" valign="top">Median</td>
<td align="center" valign="top">41%</td>
<td align="left" valign="top">30</td>
<td align="center" valign="top">173</td>
</tr>
<tr>
<td align="left" valign="top">Q1, Q3</td>
<td align="center" valign="top">36.1, 54.4</td>
<td align="left" valign="top">24, 39.6</td>
<td align="center" valign="top">102, 250</td>
</tr>
<tr>
<td align="left" valign="top" colspan="4">Other reports of reoffending after discharge</td>
</tr>
<tr>
<td align="left" valign="top">Leygraf (<xref ref-type="bibr" rid="ref34">34</xref>)</td>
<td align="center" valign="top">37%</td>
<td align="left" valign="top">48&#x2009;months</td>
<td align="center" valign="top">136</td>
</tr>
<tr>
<td align="left" valign="top">Pfaff (<xref ref-type="bibr" rid="ref35">35</xref>)</td>
<td align="center" valign="top">37%</td>
<td align="left" valign="top">Average 25.3&#x2009;months</td>
<td align="center" valign="top">41</td>
</tr>
<tr>
<td align="left" valign="top">Bezzel (<xref ref-type="bibr" rid="ref36">36</xref>)</td>
<td align="center" valign="top">19.1%</td>
<td align="left" valign="top">Average 14.4&#x2009;months</td>
<td align="center" valign="top">136</td>
</tr>
<tr>
<td align="left" valign="top">Hartl (<xref ref-type="bibr" rid="ref37">37</xref>)</td>
<td align="center" valign="top">15.5%</td>
<td align="left" valign="top">12&#x2009;months</td>
<td align="center" valign="top">76</td>
</tr>
<tr>
<td align="left" valign="top">Bezzel (<xref ref-type="bibr" rid="ref38">38</xref>)</td>
<td align="center" valign="top">16%</td>
<td align="left" valign="top">12&#x2009;months</td>
<td align="center" valign="top">102</td>
</tr>
<tr>
<td align="left" valign="top">Dudeck et al. (<xref ref-type="bibr" rid="ref39">39</xref>)</td>
<td align="center" valign="top">17%</td>
<td align="left" valign="top">12&#x2009;months</td>
<td align="center" valign="top">62</td>
</tr>
<tr>
<td align="left" valign="top">Franke et al. (<xref ref-type="bibr" rid="ref40">40</xref>)</td>
<td align="center" valign="top">14%</td>
<td align="left" valign="top">12&#x2009;months</td>
<td align="center" valign="top">272</td>
</tr>
</tbody>
</table>
</table-wrap>
<table-wrap position="float" id="tab2">
<label>Table 2</label>
<caption>
<p>Other (non-official) reports of offending during treatment.</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="left" valign="top">Study</th>
<th align="center" valign="top">Reoffending %</th>
<th align="center" valign="top">Sample size N</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="top">Schalast (<xref ref-type="bibr" rid="ref41">41</xref>)</td>
<td align="center" valign="top">24.3%</td>
<td align="center" valign="top">136</td>
</tr>
<tr>
<td align="left" valign="top">Schalast (<xref ref-type="bibr" rid="ref42">42</xref>, <xref ref-type="bibr" rid="ref43">43</xref>)</td>
<td align="center" valign="top">8.75%</td>
<td align="center" valign="top">80</td>
</tr>
<tr>
<td align="left" valign="top">Hartl (<xref ref-type="bibr" rid="ref37">37</xref>)</td>
<td align="center" valign="top">6.1%</td>
<td align="center" valign="top">76</td>
</tr>
<tr>
<td align="left" valign="top">Bezzel (<xref ref-type="bibr" rid="ref32">32</xref>)</td>
<td align="center" valign="top">6.9%</td>
<td align="center" valign="top">805</td>
</tr>
</tbody>
</table>
</table-wrap>
</sec>
<sec id="sec18">
<label>3.1.2</label>
<title>Legal and criminological</title>
<p>Studies investigating the relationship between the number of previous convictions and reconviction mostly found that patients with lengthier criminal records reoffended more frequently (<xref ref-type="bibr" rid="ref26">26</xref>&#x2013;<xref ref-type="bibr" rid="ref28">28</xref>). A study by Quereng&#x00E4;sser et al. (<xref ref-type="bibr" rid="ref20">20</xref>) using the same sample as Quereng&#x00E4;sser et al. (<xref ref-type="bibr" rid="ref44">44</xref>) found a significant relationship between number of past convictions and reconviction for patients who were transferred from forensic care to prison (which remained significant when included in a multivariate regression model) but not for patients discharged directly into the community. Butz (<xref ref-type="bibr" rid="ref28">28</xref>) found that rates of reconviction were significantly positively correlated with substance-related index offences, and that having no prior offence was linked with lower rates of reconviction. Quereng&#x00E4;sser et al. (<xref ref-type="bibr" rid="ref27">27</xref>) found a range of offences positively correlated with reconviction rates with the strength of the relationship in the following descending order: property crime, assault, an &#x2018;other&#x2019; category including traffic offences, arson, &#x2018;other&#x2019; violent crimes including attempted offences, homicide, offences against the Bet&#x00E4;ubungsmittelgesetz (BtMG; Narcotics Law), and sexual offences. Koch (<xref ref-type="bibr" rid="ref30">30</xref>) reported no significant association between index offence type and reconviction, a finding replicated in Bezzel (<xref ref-type="bibr" rid="ref32">32</xref>) study of reoffending. No consistent statement can be made on likelihood of reconviction given offence type.</p>
</sec>
<sec id="sec19">
<label>3.1.3</label>
<title>Treatment, mental and physical health</title>
<p>There was mixed evidence for the link between the recurrence of substance use during treatment and reconvictions. Gericke and Kallert (<xref ref-type="bibr" rid="ref26">26</xref>) found that patients who reused substances during treatment committed a greater number of convicted offences at follow-up; conversely, Butz (<xref ref-type="bibr" rid="ref28">28</xref>) reported that patients who reused substances less frequently had a greater number of convicted offences, and Koch (<xref ref-type="bibr" rid="ref30">30</xref>) reported a non-significant relationship. Two studies reported that the recurrence of substance use after discharge was linked to higher reoffending (<xref ref-type="bibr" rid="ref35">35</xref>, <xref ref-type="bibr" rid="ref36">36</xref>). ADHD symptoms were not significantly associated with number of reconvictions after discharge; however, ADHD symptoms were linked with a greater risk of receiving prison sentence after discharge (<xref ref-type="bibr" rid="ref45">45</xref>).</p>
</sec>
<sec id="sec20">
<label>3.1.4</label>
<title>Social and demographic</title>
<p>Patients who completed job training prior to their current treatment stay were generally less likely to have been reconvicted at follow-up than those not completing job training. However, evidence for this was mixed. While Butz (<xref ref-type="bibr" rid="ref28">28</xref>) and Quereng&#x00E4;sser et al. (<xref ref-type="bibr" rid="ref27">27</xref>) found significant negative associations with reconviction, this was not found in an earlier study by Gericke and Kallert (<xref ref-type="bibr" rid="ref26">26</xref>) who reported a non-significant relationship. In fact, a subsequent publication from Quereng&#x00E4;sser (<xref ref-type="bibr" rid="ref46">46</xref>) divided the sample into successful and unsuccessful treatment completers and found that this significant relationship only held for patients in the unsuccessful treatment group (however, it ceased to be a significant predictor in this group when included in a multivariate regression).</p>
<p>Age at admission was negatively linked with reconvictions in Butz (<xref ref-type="bibr" rid="ref28">28</xref>), but Gericke and Kallert (<xref ref-type="bibr" rid="ref26">26</xref>) reported a non-significant finding. Interestingly, Quereng&#x00E4;sser (<xref ref-type="bibr" rid="ref44">44</xref>) found a significant negative association for patients transferred to prison and then released (in both univariate and multivariate regressions), but not for patients discharged directly into the community. A similar pattern distinguished these studies on the variable &#x2018;growing up in care&#x2019;, with Butz (<xref ref-type="bibr" rid="ref28">28</xref>) finding that this was associated with reconviction, while Gericke and Kallert (<xref ref-type="bibr" rid="ref26">26</xref>) again reported a null finding. Franke et al. (<xref ref-type="bibr" rid="ref40">40</xref>) reported no significant difference in reoffending after discharge between men and women.</p>
<p>There was mixed evidence regarding the protective role of intimate relationships and social supports. Hartl (<xref ref-type="bibr" rid="ref37">37</xref>) reported that living alone at the time of the offence was predictive of reconviction; here again, Gericke and Kallert (<xref ref-type="bibr" rid="ref26">26</xref>) present a null finding. Hartl (<xref ref-type="bibr" rid="ref37">37</xref>) reported that patients who were married or widowed were reconvicted less frequently than patients who were not. In a univariate analysis, Querengaesser et al. (<xref ref-type="bibr" rid="ref44">44</xref>) also reported that marriage or being a widow reduced the likelihood of reconviction for patients who were discharged from hospital directly to prison; a significant association between relationship status and reconviction was not found for patients who were discharged directly into the community. The univariate relationship found by Querengaesser et al. (<xref ref-type="bibr" rid="ref44">44</xref>) was not replicated when controlling for other variables. Franke et al. (<xref ref-type="bibr" rid="ref40">40</xref>) found no link between reoffending and living or work situation. In relation to reoffending (as opposed to reconviction), no significant associations were identified for family status at the time of the index offence in studies by Pfaff (<xref ref-type="bibr" rid="ref35">35</xref>) and Koch (<xref ref-type="bibr" rid="ref30">30</xref>).</p>
</sec>
</sec>
<sec id="sec21">
<label>3.2</label>
<title>Treatment completion</title>
<sec id="sec22">
<label>3.2.1</label>
<title>Summary</title>
<p>Successful treatment outcome was commonly reported across the included studies, with 22 publications addressing this. See section 2.1.4 for a definition of &#x2018;treatment completion&#x2019;.</p>
<p>As can be seen in <xref ref-type="table" rid="tab3">Table 3</xref>, the median percentage of patients achieving positive and negative treatment outcomes were similar across studies (e.g., 45 and 47%, respectively). However, patients were more likely to have a negative treatment outcome. Given the varied operationalisations of treatment &#x2018;success&#x2019; and &#x2018;failure&#x2019; and sampling methods in the studies, caution should be applied when interpreting these overall findings.</p>
<table-wrap position="float" id="tab3">
<label>Table 3</label>
<caption>
<p>Treatment outcomes.</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="left" valign="top">Study</th>
<th align="center" valign="top">Positive<sup>outcome</sup></th>
<th align="center" valign="top">Negative<sup>outcome</sup></th>
<th align="center" valign="top">Other<sup>1</sup></th>
<th align="center" valign="top">Sample size N</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="top">Schalast (<xref ref-type="bibr" rid="ref41">41</xref>) and Leygraf (<xref ref-type="bibr" rid="ref34">34</xref>)</td>
<td align="center" valign="top">73.6%</td>
<td align="center" valign="top">16.2%</td>
<td align="center" valign="top">10.2%</td>
<td align="center" valign="top">136</td>
</tr>
<tr>
<td align="left" valign="top">Berger et al. (<xref ref-type="bibr" rid="ref47">47</xref>)</td>
<td align="center" valign="top">53%</td>
<td align="center" valign="top">47%</td>
<td align="center" valign="top">&#x2013;</td>
<td align="center" valign="top">103</td>
</tr>
<tr>
<td align="left" valign="top">Schalast et al. (<xref ref-type="bibr" rid="ref48">48</xref>)&#x002A;</td>
<td align="center" valign="top">36.6%</td>
<td align="center" valign="top">46.7%</td>
<td align="center" valign="top">16.7%</td>
<td align="center" valign="top">125</td>
</tr>
<tr>
<td align="left" valign="top">Gericke and Kallert (<xref ref-type="bibr" rid="ref26">26</xref>)</td>
<td align="center" valign="top">52.3%</td>
<td align="center" valign="top">47.7%</td>
<td align="center" valign="top">&#x2013;</td>
<td align="center" valign="top">277</td>
</tr>
<tr>
<td align="left" valign="top">Bezzel (<xref ref-type="bibr" rid="ref32">32</xref>)</td>
<td align="center" valign="top">33.3%</td>
<td align="center" valign="top">49.5%</td>
<td align="center" valign="top">17.2%</td>
<td align="center" valign="top">805</td>
</tr>
<tr>
<td align="left" valign="top">Schalast et al. (<xref ref-type="bibr" rid="ref49">49</xref>&#x2013;<xref ref-type="bibr" rid="ref51">51</xref>)&#x002A;</td>
<td align="center" valign="top">50%</td>
<td align="center" valign="top">48.7%</td>
<td align="center" valign="top">1.3%</td>
<td align="center" valign="top">149</td>
</tr>
<tr>
<td align="left" valign="top">Kemper (<xref ref-type="bibr" rid="ref52">52</xref>) phase 2 (2005 cohort)</td>
<td align="center" valign="top">27%</td>
<td align="center" valign="top">67%</td>
<td align="center" valign="top">6%</td>
<td align="center" valign="top">280</td>
</tr>
<tr>
<td align="left" valign="top">Hartl (<xref ref-type="bibr" rid="ref37">37</xref>)</td>
<td align="center" valign="top">43.2%</td>
<td align="center" valign="top">53.3%</td>
<td align="center" valign="top">3.5%</td>
<td align="center" valign="top">994</td>
</tr>
<tr>
<td align="left" valign="top">Rotermund et al. (<xref ref-type="bibr" rid="ref53">53</xref>)</td>
<td align="center" valign="top">53.85%</td>
<td align="center" valign="top">46.15%</td>
<td align="center" valign="top">&#x2013;</td>
<td align="center" valign="top">91</td>
</tr>
<tr>
<td align="left" valign="top">Schalast et al. (<xref ref-type="bibr" rid="ref54">54</xref>)&#x002A;</td>
<td align="center" valign="top">23.43%</td>
<td align="center" valign="top">69.7%</td>
<td align="center" valign="top">6.87%</td>
<td align="center" valign="top">175</td>
</tr>
<tr>
<td align="left" valign="top">Hartl et al. (<xref ref-type="bibr" rid="ref55">55</xref>)</td>
<td align="center" valign="top">50.5%</td>
<td align="center" valign="top">49.5%</td>
<td align="center" valign="top">&#x2013;</td>
<td align="center" valign="top">580</td>
</tr>
<tr>
<td align="left" valign="top">Quereng&#x00E4;sser et al. (<xref ref-type="bibr" rid="ref56">56</xref>)</td>
<td align="center" valign="top">38.6%</td>
<td align="center" valign="top">61.4%</td>
<td align="center" valign="top">&#x2013;</td>
<td align="center" valign="top">777</td>
</tr>
<tr>
<td align="left" valign="top">Schalast et al. (<xref ref-type="bibr" rid="ref57">57</xref>)&#x002A;</td>
<td align="center" valign="top">47.3%</td>
<td align="center" valign="top">48.57%</td>
<td align="center" valign="top">4.13%</td>
<td align="center" valign="top">315</td>
</tr>
<tr>
<td align="left" valign="top">Rosch et al. (<xref ref-type="bibr" rid="ref58">58</xref>)</td>
<td align="center" valign="top">24.6%</td>
<td align="center" valign="top">35.9%</td>
<td align="center" valign="top">39.5%</td>
<td align="center" valign="top">357</td>
</tr>
<tr>
<td align="left" valign="top">Ross et al. (<xref ref-type="bibr" rid="ref59">59</xref>)</td>
<td align="center" valign="top">45.1%</td>
<td align="center" valign="top">54.9%</td>
<td align="center" valign="top">&#x2013;</td>
<td align="center" valign="top">1,467</td>
</tr>
<tr>
<td align="left" valign="top">Franke et al. (<xref ref-type="bibr" rid="ref40">40</xref>)</td>
<td align="center" valign="top">38.3%</td>
<td align="center" valign="top">&#x2013;</td>
<td align="center" valign="top">61.7%<sup>2</sup></td>
<td align="center" valign="top">501</td>
</tr>
<tr>
<td align="left" valign="top">Berthold (<xref ref-type="bibr" rid="ref17">17</xref>)</td>
<td align="center" valign="top">61.9%</td>
<td align="center" valign="top">38.1%</td>
<td/>
<td align="center" valign="top">328</td>
</tr>
<tr>
<td align="left" valign="top">Lutz et al. (<xref ref-type="bibr" rid="ref60">60</xref>)</td>
<td align="center" valign="top">63%</td>
<td align="center" valign="top">34%</td>
<td align="center" valign="top">&#x2013;</td>
<td align="center" valign="top">1884</td>
</tr>
<tr>
<td align="left" valign="top">Reiners et al. (<xref ref-type="bibr" rid="ref25">25</xref>)<sup>3</sup></td>
<td align="center" valign="top">15%</td>
<td align="center" valign="top">18%</td>
<td align="center" valign="top">&#x2013;</td>
<td align="center" valign="top">2,483</td>
</tr>
<tr>
<td align="left" valign="top">Median</td>
<td align="center" valign="top">45.1%</td>
<td align="center" valign="top">47.7%</td>
<td align="center" valign="top">1.3</td>
<td align="center" valign="top">328</td>
</tr>
<tr>
<td align="left" valign="top">Q1, Q3</td>
<td align="center" valign="top">35.0, 52.65%</td>
<td align="center" valign="top">37, 51.4%</td>
<td align="center" valign="top">0, 8.5%</td>
<td align="center" valign="top">162, 791</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<p>&#x002A;Essener Evaluation study. <sup>1</sup>Other, Death or still being in treatment at time of data collection. <sup>2</sup>Described as the &#x2018;possibility of parole&#x2019;. <sup>3</sup>Not all patients were discharged over the time period studied (i.e., 2018). Only cohort or cross-sectional studies are included in this table. Other studies of, for example, a small number of patients following an intervention where treatment outcome was assessed are not included (these include: Seibold (<xref ref-type="bibr" rid="ref61">61</xref>), <italic>N</italic>&#x2009;=&#x2009;16; Quereng&#x00E4;sser (<xref ref-type="bibr" rid="ref46">46</xref>), <italic>N</italic>&#x2009;=&#x2009;12; Fontao et al. (<xref ref-type="bibr" rid="ref62">62</xref>); <italic>N</italic>&#x2009;=&#x2009;17). &#x2018;&#x2013;&#x2019; values included in median calculations as &#x2018;0&#x2019;.</p>
</table-wrap-foot>
</table-wrap>
</sec>
<sec id="sec23">
<label>3.2.2</label>
<title>Legal and criminological</title>
<p>The number of previous criminal convictions was clearly linked with treatment completion, with seven studies finding that patients who were successfully discharged from care had significantly fewer past convictions (<xref ref-type="bibr" rid="ref26">26</xref>, <xref ref-type="bibr" rid="ref32">32</xref>, <xref ref-type="bibr" rid="ref47">47</xref>, <xref ref-type="bibr" rid="ref48">48</xref>, <xref ref-type="bibr" rid="ref51">51</xref>, <xref ref-type="bibr" rid="ref56">56</xref>, <xref ref-type="bibr" rid="ref57">57</xref>). Three studies found that patients who had committed substance-related index offences were more likely to have a successful treatment outcome than patients with violent or property-related index offences (<xref ref-type="bibr" rid="ref17">17</xref>, <xref ref-type="bibr" rid="ref37">37</xref>, <xref ref-type="bibr" rid="ref56">56</xref>). Conversely, Kemper (<xref ref-type="bibr" rid="ref52">52</xref>) found that patients (<italic>n</italic>&#x2009;=&#x2009;280) with violent index offences were less likely to have a successful outcome &#x2013; a finding that remained significant in a subsequent multivariate analysis, though this finding was not reproduced in phase 2 of this study. Three studies reported that longer parallel sentences (prison sentences ordered to run alongside treatment) were associated with treatment completion (<xref ref-type="bibr" rid="ref32">32</xref>, <xref ref-type="bibr" rid="ref56">56</xref>, <xref ref-type="bibr" rid="ref57">57</xref>); while two found no evidence for this (<xref ref-type="bibr" rid="ref48">48</xref>, <xref ref-type="bibr" rid="ref51">51</xref>).</p>
</sec>
<sec id="sec24">
<label>3.2.3</label>
<title>Treatment, mental and physical health</title>
<p>Links between adverse events, substance use and psychopathy with treatment completion were explored. Patients who completed treatment successfully had significantly fewer escapes/absconding events during treatment (<xref ref-type="bibr" rid="ref26">26</xref>, <xref ref-type="bibr" rid="ref32">32</xref>, <xref ref-type="bibr" rid="ref37">37</xref>, <xref ref-type="bibr" rid="ref56">56</xref>). Three studies found that patients who did not reuse substances during treatment were more likely to successfully compete treatment (<xref ref-type="bibr" rid="ref32">32</xref>, <xref ref-type="bibr" rid="ref37">37</xref>, <xref ref-type="bibr" rid="ref56">56</xref>), but two studies reported null findings (<xref ref-type="bibr" rid="ref26">26</xref>, <xref ref-type="bibr" rid="ref48">48</xref>). While three studies found no evidence that patients whose main substance used was alcohol were more likely to successfully complete treatment [(<xref ref-type="bibr" rid="ref26">26</xref>, <xref ref-type="bibr" rid="ref32">32</xref>, <xref ref-type="bibr" rid="ref52">52</xref>), phase 2]; one study did report this finding (<xref ref-type="bibr" rid="ref47">47</xref>). Kemper (<xref ref-type="bibr" rid="ref52">52</xref>) found that patients with a personality disorder were significantly more likely to have an &#x2018;irregular&#x2019; or unsuccessful treatment outcome, though this finding was not replicated in phase 2 of this study, and Berthold and Riedemann (<xref ref-type="bibr" rid="ref17">17</xref>) also found no link with personality disorder. Relatedly, Berger (<xref ref-type="bibr" rid="ref63">63</xref>) reported that psychopathy scores were higher in patients who did not complete treatment. No significant difference in successful treatment outcomes was found when comparing hospitals that offered opioid agonist treatment (OAT) and those that did not; though a significantly higher rate of treatment termination without success was observed in hospitals offering OAT (<xref ref-type="bibr" rid="ref25">25</xref>). No difference was found for patients receiving/not receiving substitution treatment in Berthold and Riedemann (<xref ref-type="bibr" rid="ref17">17</xref>). Treatment outcome was not linked to presence of ADHD symptoms [(<xref ref-type="bibr" rid="ref45">45</xref>, <xref ref-type="bibr" rid="ref48">48</xref>, <xref ref-type="bibr" rid="ref51">51</xref>, <xref ref-type="bibr" rid="ref54">54</xref>, <xref ref-type="bibr" rid="ref57">57</xref>); with the exception of two findings in which hyperactivity and inattentiveness were linked in (<xref ref-type="bibr" rid="ref48">48</xref>), and attentiveness in (<xref ref-type="bibr" rid="ref51">51</xref>)].</p>
<p>Several studies measured treatment motivation. As different operationalisations were used to investigate this, second-order knowledge claims should be made with caution; however, the cumulative results do implicate an important role for treatment motivation for treatment completion. Schalast (<xref ref-type="bibr" rid="ref43">43</xref>) found an association between a composite outcome variable (called a &#x2018;problem coefficient&#x2019;, comprising: reoffending, escape, and the recurrence of substance use) and motivational disposition measured across several variables such as resolve to stay abstinent, hope for therapy, and cooperativeness. Using a questionnaire-based measure of therapeutic alliance with a subdomain of &#x2018;engagement&#x2019;, Fontao et al. (<xref ref-type="bibr" rid="ref62">62</xref>) found significant differences for successful and unsuccessful completers, with higher engagement scores in the former group. Quereng&#x00E4;sser et al. (<xref ref-type="bibr" rid="ref64">64</xref>) identified ambiguous treatment motivation as one of several reasons given for treatment failure in a retrospective cross-sectional study. Treatment motivation was assessed by the authors by looking for evidence of motivation in statements written by therapists, a method the authors describe as subjective and open to interpretation. Using latent class analysis and regression methods, Rosch et al. (<xref ref-type="bibr" rid="ref58">58</xref>) developed three groups of offenders: the group for whom treatment completion was most likely was characterised, among other things, by higher treatment motivation. Passow et al. (<xref ref-type="bibr" rid="ref33">33</xref>) found that patients who were motivated to stay abstinent reoffended less frequently after discharge than their peers. Quereng&#x00E4;sser et al. (<xref ref-type="bibr" rid="ref46">46</xref>) found a non-significant link with treatment completion but had a sample of only <italic>N</italic>&#x2009;=&#x2009;12.</p>
</sec>
<sec id="sec25">
<label>3.2.4</label>
<title>Social and demographic</title>
<p>Educational and vocational variables were examined, with evidence of association with treatment outcomes mixed. Patients with successful treatment outcomes were more likely to have completed job training in three studies (<xref ref-type="bibr" rid="ref37">37</xref>, <xref ref-type="bibr" rid="ref47">47</xref>, <xref ref-type="bibr" rid="ref61">61</xref>), but five studies reported that this relationship was non-significant (<xref ref-type="bibr" rid="ref17">17</xref>, <xref ref-type="bibr" rid="ref26">26</xref>, <xref ref-type="bibr" rid="ref48">48</xref>, <xref ref-type="bibr" rid="ref51">51</xref>, <xref ref-type="bibr" rid="ref57">57</xref>). Three studies found that treatment completion was associated with having obtained a high school degree (<xref ref-type="bibr" rid="ref32">32</xref>, <xref ref-type="bibr" rid="ref37">37</xref>, <xref ref-type="bibr" rid="ref47">47</xref>); while three studies led by Schalast found this not to be the case (<xref ref-type="bibr" rid="ref48">48</xref>, <xref ref-type="bibr" rid="ref51">51</xref>, <xref ref-type="bibr" rid="ref57">57</xref>). Patients who were employed prior to treatment were more likely to complete treatment successfully in three studies (<xref ref-type="bibr" rid="ref48">48</xref>, <xref ref-type="bibr" rid="ref51">51</xref>, <xref ref-type="bibr" rid="ref56">56</xref>); however, one study did not report this: Schalast et al. (<xref ref-type="bibr" rid="ref57">57</xref>). Men were more likely to have a negative treatment outcome in Franke et al. (<xref ref-type="bibr" rid="ref40">40</xref>) and Hartl (<xref ref-type="bibr" rid="ref37">37</xref>); though no significant difference was observed in Berthold and Riedemann (<xref ref-type="bibr" rid="ref17">17</xref>). Patients with a migration background were less likely to be successfully discharged from services (<xref ref-type="bibr" rid="ref60">60</xref>). Berthold and Riedemann (<xref ref-type="bibr" rid="ref17">17</xref>) found no link between age and treatment outcome.</p>
<p>Living with a partner before entering treatment was linked with positive treatment outcomes in two studies (<xref ref-type="bibr" rid="ref32">32</xref>, <xref ref-type="bibr" rid="ref37">37</xref>); but not in the study by Gericke and Kallert (<xref ref-type="bibr" rid="ref26">26</xref>). Three studies found that patients who were not brought up in care were more likely than their peers who were brought up in care to complete treatment successfully (<xref ref-type="bibr" rid="ref26">26</xref>, <xref ref-type="bibr" rid="ref48">48</xref>, <xref ref-type="bibr" rid="ref51">51</xref>); one study reported null findings in relation to this factor (<xref ref-type="bibr" rid="ref57">57</xref>).</p>
</sec>
</sec>
<sec id="sec26">
<label>3.3</label>
<title>The recurrence of substance use</title>
<sec id="sec27">
<label>3.3.1</label>
<title>Summary</title>
<p>Eleven studies investigated <italic>the recurrence of substance use during treatment</italic>; see <xref ref-type="table" rid="tab4">Table 4</xref>. The sample sizes in these studies ranged from <italic>N</italic>&#x2009;=&#x2009;39 to <italic>N</italic>&#x2009;=&#x2009;805, with the &#x2018;follow-up&#x2019; period defined as the length of a patient&#x2019;s inpatient treatment which varied from 12 to 24 months. On average across these studies, slightly over half of the patients reused, with reuse rates ranging from 16.7 to 81.6%.</p>
<table-wrap position="float" id="tab4">
<label>Table 4</label>
<caption>
<p>Rates of the recurrence of substance use during treatment.</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="left" valign="top">Study</th>
<th align="center" valign="top">Reuse %</th>
<th align="center" valign="top">Sample size N</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="top">Koch (<xref ref-type="bibr" rid="ref30">30</xref>)</td>
<td align="center" valign="top">38.1%</td>
<td align="center" valign="top">97</td>
</tr>
<tr>
<td align="left" valign="top">Schalast (<xref ref-type="bibr" rid="ref41">41</xref>)</td>
<td align="center" valign="top">81.6%</td>
<td align="center" valign="top">136</td>
</tr>
<tr>
<td align="left" valign="top">Dessecker (<xref ref-type="bibr" rid="ref31">31</xref>)</td>
<td align="center" valign="top">79%</td>
<td align="center" valign="top">249</td>
</tr>
<tr>
<td align="left" valign="top">Seifert and Leygraf (<xref ref-type="bibr" rid="ref65">65</xref>)</td>
<td align="center" valign="top">29.9%</td>
<td align="center" valign="top">144</td>
</tr>
<tr>
<td align="left" valign="top">Schalast (<xref ref-type="bibr" rid="ref43">43</xref>)</td>
<td align="center" valign="top">55%</td>
<td align="center" valign="top">80</td>
</tr>
<tr>
<td align="left" valign="top">Schalast et al. (<xref ref-type="bibr" rid="ref48">48</xref>)</td>
<td align="center" valign="top">17.3%</td>
<td align="center" valign="top">125</td>
</tr>
<tr>
<td align="left" valign="top">Gericke and Kallert (<xref ref-type="bibr" rid="ref26">26</xref>)</td>
<td align="center" valign="top">45.85%</td>
<td align="center" valign="top">277</td>
</tr>
<tr>
<td align="left" valign="top">Bezzel (<xref ref-type="bibr" rid="ref32">32</xref>)</td>
<td align="center" valign="top">55%</td>
<td align="center" valign="top">805</td>
</tr>
<tr>
<td align="left" valign="top">Berger (<xref ref-type="bibr" rid="ref63">63</xref>)</td>
<td align="center" valign="top">16.7%</td>
<td align="center" valign="top">102</td>
</tr>
<tr>
<td align="left" valign="top">Hartl (<xref ref-type="bibr" rid="ref37">37</xref>)</td>
<td align="center" valign="top">54.5%</td>
<td align="center" valign="top">76</td>
</tr>
<tr>
<td align="left" valign="top">Quereng&#x00E4;sser et al. (<xref ref-type="bibr" rid="ref64">64</xref>)</td>
<td align="center" valign="top">64.1%</td>
<td align="center" valign="top">39</td>
</tr>
</tbody>
</table>
</table-wrap>
<p>Nine studies reported <italic>the recurrence of substance use after discharge</italic>; see <xref ref-type="table" rid="tab5">Table 5</xref>. Sample sizes in these studies ranged from <italic>N</italic>&#x2009;=&#x2009;41 to <italic>N</italic>&#x2009;=&#x2009;501. Not all studies reported average follow-up periods, but these ranged from 12 to 42&#x2009;months after discharge. The rate of substance reuse across these studies ranged from 34.9 to 85.4%.</p>
<table-wrap position="float" id="tab5">
<label>Table 5</label>
<caption>
<p>Rates of the recurrence of substance use after discharge.</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="left" valign="top">Study</th>
<th align="center" valign="top">Reuse %</th>
<th align="center" valign="top">Sample size N</th>
<th align="left" valign="top">Follow-up period</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="top">Koch (<xref ref-type="bibr" rid="ref30">30</xref>)</td>
<td align="center" valign="top">83.8%</td>
<td align="center" valign="top">63</td>
<td align="left" valign="top">Average 30&#x2009;months</td>
</tr>
<tr>
<td align="left" valign="top">Dessecker (<xref ref-type="bibr" rid="ref31">31</xref>)</td>
<td align="center" valign="top">69%</td>
<td align="center" valign="top">249</td>
<td align="left" valign="top">24&#x2009;months</td>
</tr>
<tr>
<td align="left" valign="top">Pfaff (<xref ref-type="bibr" rid="ref35">35</xref>)</td>
<td align="center" valign="top">63%</td>
<td align="center" valign="top">41</td>
<td align="left" valign="top">Average 24&#x2009;months</td>
</tr>
<tr>
<td align="left" valign="top">Bezzel (<xref ref-type="bibr" rid="ref32">32</xref>)</td>
<td align="center" valign="top">47.9%</td>
<td align="center" valign="top">173</td>
<td align="left" valign="top">12&#x2009;months</td>
</tr>
<tr>
<td align="left" valign="top">Bezzel (<xref ref-type="bibr" rid="ref36">36</xref>)</td>
<td align="center" valign="top">34.9%</td>
<td align="center" valign="top">136</td>
<td align="left" valign="top">Average 14.2&#x2009;months</td>
</tr>
<tr>
<td align="left" valign="top">Hartl (<xref ref-type="bibr" rid="ref37">37</xref>)</td>
<td align="center" valign="top">59%</td>
<td align="center" valign="top">76</td>
<td align="left" valign="top">12&#x2009;months</td>
</tr>
<tr>
<td align="left" valign="top">Passow et al. (<xref ref-type="bibr" rid="ref33">33</xref>)</td>
<td align="center" valign="top">85.4%</td>
<td align="center" valign="top">84</td>
<td align="left" valign="top">36&#x2013;48&#x2009;months</td>
</tr>
<tr>
<td align="left" valign="top">Dudeck et al. (<xref ref-type="bibr" rid="ref39">39</xref>)</td>
<td align="center" valign="top">44%</td>
<td align="center" valign="top">62</td>
<td align="left" valign="top">12&#x2009;months</td>
</tr>
<tr>
<td align="left" valign="top">Franke et al. (<xref ref-type="bibr" rid="ref40">40</xref>)</td>
<td align="center" valign="top">39%</td>
<td align="center" valign="top">501</td>
<td align="left" valign="top">12&#x2009;months</td>
</tr>
</tbody>
</table>
</table-wrap>
<p>Six studies examined factors associated with the recurrence of substance use during or after discharge. Fifteen such factors were investigated with only one being included in more than one study. Two studies reported that patients whose main substance use problem was alcohol use were less likely to reuse substances during treatment compared to patients for whom their main substance use problem was defined as any other substance (<xref ref-type="bibr" rid="ref32">32</xref>, <xref ref-type="bibr" rid="ref37">37</xref>). Schalast (<xref ref-type="bibr" rid="ref43">43</xref>) confirmed these findings when investigating patients at a six-month follow-up, but reported that this distinction was no longer significant at 12&#x2009;months.</p>
</sec>
</sec>
</sec>
<sec sec-type="discussion" id="sec28">
<label>4</label>
<title>Discussion</title>
<p>This review synthesised the literature describing studies of the mandatory substance treatment patient population in Germany (&#x00A7;64 German Penal Code) in relation to three primary outcomes: reconviction/reoffending, treatment completion, and the recurrence of substance use. In many ways, our review reports similar findings to the German language reviews by Fries (<xref ref-type="bibr" rid="ref21">21</xref>) and Quereng&#x00E4;sser and Baur (<xref ref-type="bibr" rid="ref22">22</xref>, <xref ref-type="bibr" rid="ref23">23</xref>). The general picture suggests that certain risk factors for reconviction/reoffending identified in the general offender population (e.g., greater number of past convictions, lower age at conviction) were also associated with reconviction/reoffending in this population but that very few clear patterns emerged across all studies; that dynamic factors, such as higher levels of treatment motivation, are important predictors of treatment completion, but are under-researched compared to static and historic factors; and that the evidence-base for this population is mixed, often due to heterogeneity in research methods/construct operationalisation. The take-home messages from this review and suggestions for future research are discussed below.</p>
<sec id="sec29">
<label>4.1</label>
<title>Reconviction and reoffending</title>
<p>On average, reconviction rates (Mdn&#x2009;=&#x2009;41% over Mdn&#x2009;=&#x2009;30&#x2009;months) were higher than those reported for forensic patients in Germany with major mental disorders [receiving treatment under &#x00A7;63 German Penal Code; e.g., 35.2% across a mean follow-up of 16.5&#x2009;years reported in Seifert et al. (<xref ref-type="bibr" rid="ref66">66</xref>)]. Franke et al. (<xref ref-type="bibr" rid="ref40">40</xref>) directly compared the reconviction/reoffending rates of these two groups in a single federal state and confirmed higher recidivism rates in patients with substance use disorders (SUD). The rates found in our review are also higher than reconviction rates for non-forensic patients leaving prison settings in Germany: approximately 34% of people leaving prisons reoffend within 3&#x2009;years (<xref ref-type="bibr" rid="ref67">67</xref>). While indicative of the outcomes for the forensic SUD population, these groups are not entirely comparable as individuals have not been matched on factors like age, index offence type, and gender as part of a single prospective study.</p>
<p>Our finding that predictors of reoffending differed in some ways for successful and unsuccessful completers (e.g., number of past convictions, completed job training, age, marital status) might reflect wider national debates about the appropriateness of the &#x00A7;64 German Penal Code treatment order for a large number of people (<xref ref-type="bibr" rid="ref19">19</xref>). A higher number of past convictions, a lack of job training completion prior to their current forensic treatment, a lower age at admission, and being single were significantly positively correlated with reconviction/offending for patients transferred to prison; while no significant associations were reported between these variables and reconviction/offending for patients transferred to the community. The unsuccessful completers might more closely resemble general (i.e., non-forensic) population offenders, for whom most models predicting reoffending have been developed and thus explain why some predictors were more predictive of reconviction in this group.</p>
</sec>
<sec id="sec30">
<label>4.2</label>
<title>Treatment outcome</title>
<p>Across 22 publications in our review, patients were on average more likely to have a negative treatment outcome than a positive treatment outcome (47 vs. 45% respectively; though note the limitations section when considering this median value). This pattern is repeated in several of the largest studies. The importance of this is compounded by studies demonstrating that unsuccessful completers reoffend at higher rates than patients completing treatment successfully (<xref ref-type="bibr" rid="ref40">40</xref>). One possible explanatory factor here might be <italic>systemic,</italic> that courts are sentencing people to mandatory SUD treatment based on incorrect assumptions about the helpfulness of treatment or broad interpretations of the &#x00A7;64 StGB treatment order by courts or psychiatric experts (<xref ref-type="bibr" rid="ref40">40</xref>). A second factor might point to the <italic>absence of readiness/motivation</italic> as an important predictor of engagement and success. Motivation has been identified as a key antecedent to positive outcomes in substance use programme participation and recidivism in the international literature (<xref ref-type="bibr" rid="ref12">12</xref>, <xref ref-type="bibr" rid="ref14">14</xref>, <xref ref-type="bibr" rid="ref68">68</xref>); in our review (see section 3.2.3); and is viewed by staff as an important factor in treatment outcome in this population (<xref ref-type="bibr" rid="ref69">69</xref>, <xref ref-type="bibr" rid="ref70">70</xref>). A third factor might be <italic>methodological:</italic> treatment effects could be moderated by evaluation methods, program features, and treatment contexts.</p>
<p>A recent study highlights the possible role of demographics in the effectiveness of treatment. Berthold and Riedemann (<xref ref-type="bibr" rid="ref17">17</xref>) used data collected in a large national survey of 2046 &#x00A7;64 StGB patients. A multivariate regression (<italic>N</italic>&#x2009;=&#x2009;326) indicated that three variables were significant predictors of treatment completion: being in work in the 6&#x2009;months prior to the index offence and intoxication at time of the index offence were associated with greater odds of treatment completion; having a migration background was associated with greater odds of treatment failure.</p>
<p>Explaining this latter finding, the authors propose that treatment engagement might by affected by lack of knowledge of the German language and provision of support in a range of languages, not migration background <italic>per se</italic>. Ross et al. (<xref ref-type="bibr" rid="ref71">71</xref>) note that forensic patients with a migration background in Germany face a range of factors that complicate their health and social needs, including socioeconomic status, racism, access to education, fleeing from war or persecution, factors linked to precarious travel from home countries, and the cultural and linguistic adaptations to life in Germany. These factors are linked to challenges in assessment and treatment engagement (<xref ref-type="bibr" rid="ref72">72</xref>). It should be noted that Kemper (<xref ref-type="bibr" rid="ref52">52</xref>) found no significant link between either nationality or language difficulties and treatment outcome, however. The regression in Berthold &#x0026; Riedemann (<xref ref-type="bibr" rid="ref17">17</xref>) accounted for 24% of outcome variance, thus leaving considerable room for further explanatory factors. The only variables consistently associated with successful treatment completion across multiple studies in our review was the occurrence of escapes/absconding events and number of past convictions (successful treatment completers had significantly fewer escapes/absconding events and past convictions).</p>
</sec>
<sec id="sec31">
<label>4.3</label>
<title>Recurrence of substance use</title>
<p>Studies of the recurrence of substance use included in our review found that approximately half of all patients reused substances during treatment, and around 60% reused after discharge, with follow-up periods ranging from 12 to 48 months. Reviews have highlighted high substance use recurrence rates across a range of substances in the general population during and after treatment (<xref ref-type="bibr" rid="ref73">73</xref>). These recurrences can occur soon after initiating treatment, with several studies reporting recurrence of substance use within weeks to months in two-thirds of some study participants (<xref ref-type="bibr" rid="ref73">73</xref>). A comparative study of outcomes for (a) criminal justice-mandated patients (<italic>n</italic>&#x2009;=&#x2009;141), (b) justice-involved, non-mandated patients (<italic>n</italic>&#x2009;=&#x2009;235), and (c) patients not involved in the CJS following substance use treatment in the US (<italic>n</italic>&#x2009;=&#x2009;1,719) found that 53.9, 45.3 and 39.9% of people in these groups, respectively, remained abstinent after 1&#x2009;year (<xref ref-type="bibr" rid="ref74">74</xref>). Higher abstinence rates for the criminal justice-mandated patients were not explained by before-treatment differences.</p>
</sec>
<sec id="sec32">
<label>4.4</label>
<title>Robustness of the synthesis and directions for future research</title>
<p>Overall, the findings of our review suggest that although a large number of studies have been conducted to identify the predictors of successful treatment and criminological outcomes for this population, there remain three problem areas. The first is <italic>methodological</italic>; although many studies in our review tested the same relationships between x and y variables (e.g., vocational training and reconviction), the operationalisations of these varied widely, particularly at the predictor level. This renders meta-analysis unsuitable. The second is <italic>practical</italic>; most variables are static and historical as these are easier to routinely collect. This neglects important dynamic treatment and risk factors that are known to be important for predicting outcomes (<xref ref-type="bibr" rid="ref75">75</xref>&#x2013;<xref ref-type="bibr" rid="ref77">77</xref>). The third is <italic>conceptual</italic>; study authors [with a few exceptions, e.g., speaking patterns in a therapeutic programme as an indicator of engagement in Quereng&#x00E4;sser (<xref ref-type="bibr" rid="ref46">46</xref>)] did not choose variables/factors that fall firmly within recent developments in offender rehabilitation, namely strength- and recovery-based approaches, or risk assessment that incorporates protective factors or shared risk assessment. None of the included studies explicitly measured domains of personal recovery, protective factors, fundamental goods as identified in the Good Lives Model (<xref ref-type="bibr" rid="ref78">78</xref>), or patient participation in treatment, for example in shared risk assessment (<xref ref-type="bibr" rid="ref79">79</xref>). A growing body of literature supports the claim that strength- and recovery-based models of treatment are valuable concomitants to medical, risk, or deficit-based approaches (<xref ref-type="bibr" rid="ref80">80</xref>).</p>
<p>Researchers should therefore agree upon variable operationalisations and methods of data imputation and collection. This can be achieved by the widespread adoption, expansion and harmonisation of pre-existing surveys and databases. Berthold and Riedemann (<xref ref-type="bibr" rid="ref17">17</xref>, <xref ref-type="bibr" rid="ref81">81</xref>) annually collect data from across Germany: the &#x2018;&#x00A7;64 StGB Stichtagserhebung&#x2019; (&#x2018;cut-off date survey&#x2019;). A nationwide effort should be undertaken to adopt this in all forensic hospitals with forensic patients receiving &#x00A7;64 StGB care for SUDs. In furtherance to this nation-wide survey/database, a working group should be established to choose routinely used measures of strength- and recovery-based treatment. Given the relevance of therapeutic milieu and the efficacy of therapeutic community (TC) approaches, measures of ward atmosphere would also be beneficial (<xref ref-type="bibr" rid="ref82">82</xref>). Further, researchers should ensure they consider gender differences in outcomes as some recent research of this population found that differences in outcomes across sex can be observed: a similar proportion of men (55%) and women (55%) completed treatment, whereas men (42%) were more likely to be released to prison than women (29%); rehospitalisation was significantly linked to homelessness and unemployment in women but not men (<xref ref-type="bibr" rid="ref40">40</xref>).</p>
</sec>
<sec id="sec33">
<label>4.5</label>
<title>Limitations</title>
<p>Several limitations of this review should be acknowledged. First, literature for this review was sought by using search terms in the English language. This returned a reasonable number of relevant hits. However, the number of eligible publications found following hand searches of the reference lists of the initially returned hits suggests that (A) the initial search should have been conducted in the German language too, but (B) the low number of relevant results was compensated for as 245 potentially relevant publications were subject to full-text review and 26 publications were included. Second, it was not always possible to discern how authors operationalised certain variables, such as treatment &#x2018;success&#x2019; or &#x2018;failure&#x2019;. We have attempted to be as consistent and clear as possible in reporting results and to inform the reader of these differences across studies; we also chose not to undertake a meta-analysis for this reason. Third, it was not always clear across different studies whether the same or overlapping samples were reported upon. Where this was clearer (e.g., Essener Evaluation Study) we indicated this. However, it is possible some patient data have been reported on more than once. Fourth, median values presented in this review are taken from a range of studies with various sampling methods (e.g., cohort, cross-sectional). Therefore, median values are indicative only and cannot be said to be definitive and generalisable for all patients at all hospitals in Germany. Finally, reoffending and reconviction offence categories and types of substances were not widely reported in studies. Predictors of reoffending, reconviction, and substance use will likely be different for different offence categories and substance types, so this should also be considered in future research.</p>
</sec>
</sec>
<sec sec-type="conclusions" id="sec34">
<label>5</label>
<title>Conclusion</title>
<p>Evidence of the effectiveness of mandatory substance use treatment is mixed. Criminal justice-involved persons with substance use disorders in Germany can be ordered to received mandatory treatment in forensic hospitals (&#x00A7;64 German Penal Code). A concerted effort has been undertaken by researchers to identify predictors of recidivism, treatment completion, and the recurrence of substance use in this population. Predictors of recidivism in some ways reflect wider models predicting recidivism (e.g., age), but in many cases evidence was mixed (e.g., job training completion prior to treatment). The explanatory power of models predicting treatment completion and heterogeneity in findings in relation to this outcome suggest that more sophisticated studies using dynamic variables are needed. Much of this body of research suffers from methodological, practical, and conceptual limitations. The appropriateness and ethics of mandatory treatment under &#x00A7;64 German Penal Code for this population are current topics of debate in German forensic mental health.</p>
</sec>
<sec sec-type="data-availability" id="sec35">
<title>Data availability statement</title>
<p>The original contributions presented in the study are included in the article/supplementary material, further inquiries can be directed to the corresponding author.</p>
</sec>
<sec sec-type="author-contributions" id="sec36">
<title>Author contributions</title>
<p>BV: article conception, second draft, and editing. JT: article conception, first draft, data extraction and synthesis, and editing. JW: data extraction and synthesis. EM: data extraction and synthesis. All authors contributed to the article and approved the submitted version.</p>
</sec>
</body>
<back>
<ack>
<p>The authors would like to thank Peggy Walde and Rebekka Braatz for their help screening titles for inclusion and data extraction.</p>
</ack>
<sec sec-type="COI-statement" id="sec37">
<title>Conflict of interest</title>
<p>The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.</p>
</sec>
<sec id="sec100" sec-type="disclaimer">
<title>Publisher&#x2019;s note</title>
<p>All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.</p>
</sec>
<ref-list>
<title>References</title>
<ref id="ref1"><label>1.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Perry</surname><given-names>AE</given-names></name> <name><surname>Darwin</surname><given-names>Z</given-names></name> <name><surname>Godfrey</surname><given-names>C</given-names></name> <name><surname>McDougall</surname><given-names>C</given-names></name> <name><surname>Lunn</surname><given-names>J</given-names></name> <name><surname>Glanville</surname><given-names>J</given-names></name> <etal/></person-group>. <article-title>The effectiveness of interventions for drug-using offenders in the courts, secure establishments and the community: a systematic review</article-title>. <source>Subst Use Misuse</source>. (<year>2009</year>) <volume>44</volume>:<fpage>374</fpage>&#x2013;<lpage>400</lpage>. doi: <pub-id pub-id-type="doi">10.1080/10826080802347560</pub-id></citation></ref>
<ref id="ref2"><label>2.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Goldstein</surname><given-names>PJ</given-names></name></person-group>. <article-title>The drugs/violence Nexus: a tripartite conceptual framework</article-title>. <source>J Drug Issues</source>. (<year>1985</year>) <volume>15</volume>:<fpage>493</fpage>&#x2013;<lpage>506</lpage>. doi: <pub-id pub-id-type="doi">10.1177/002204268501500406</pub-id></citation></ref>
<ref id="ref3"><label>3.</label><citation citation-type="other"><person-group person-group-type="author"><collab id="coll1">UNDOC &#x0026; WHO</collab></person-group>. (<year>2018</year>). Treatment and care for people with drug use disorders in contact with the criminal justice system. Alternatives to Conviction or Punishment. Available at: <ext-link xlink:href="https://www.unodc.org/documents/UNODC_WHO_Alternatives_to_Conviction_or_Punishment_2018.pdf" ext-link-type="uri">https://www.unodc.org/documents/UNODC_WHO_Alternatives_to_Conviction_or_Punishment_2018.pdf</ext-link></citation></ref>
<ref id="ref4"><label>4.</label><citation citation-type="book"><person-group person-group-type="author"><name><surname>Measham</surname><given-names>F</given-names></name> <name><surname>South</surname><given-names>N</given-names></name></person-group>. <article-title>Drugs, alcohol, and crime</article-title> In: Liebling A, Maruna S, McAra L, editors. <source>The Oxford Handbook of Criminology</source>. <publisher-loc>Oxford</publisher-loc>: <publisher-name>Oxford University Press</publisher-name> (<year>2012</year>). <fpage>686</fpage>&#x2013;<lpage>716</lpage>.</citation></ref>
<ref id="ref5"><label>5.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Bonta</surname><given-names>J</given-names></name> <name><surname>Blais</surname><given-names>J</given-names></name> <name><surname>Wilson</surname><given-names>HA</given-names></name></person-group>. <article-title>A theoretically informed meta-analysis of the risk for general and violent recidivism for mentally disordered offenders</article-title>. <source>Aggress Violent Behav</source>. (<year>2014</year>) <volume>19</volume>:<fpage>278</fpage>&#x2013;<lpage>87</lpage>. doi: <pub-id pub-id-type="doi">10.1016/j.avb.2014.04.014</pub-id></citation></ref>
<ref id="ref6"><label>6.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Witt</surname><given-names>K</given-names></name> <name><surname>van Dorn</surname><given-names>R</given-names></name> <name><surname>Fazel</surname><given-names>S</given-names></name></person-group>. <article-title>Risk factors for violence in psychosis: systematic review and meta-regression analysis of 110 studies</article-title>. <source>PloS One</source>. (<year>2013</year>) <volume>8</volume>:<fpage>e55942</fpage>. doi: <pub-id pub-id-type="doi">10.1371/journal.pone.0055942</pub-id>, PMID: <pub-id pub-id-type="pmid">23418482</pub-id></citation></ref>
<ref id="ref7"><label>7.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Fazel</surname><given-names>S</given-names></name> <name><surname>Yoon</surname><given-names>IA</given-names></name> <name><surname>Hayes</surname><given-names>AJ</given-names></name></person-group>. <article-title>Substance use disorders in prisoners: an updated systematic review and meta-regression analysis in recently incarcerated men and women</article-title>. <source>Addiction</source>. (<year>2017</year>) <volume>112</volume>:<fpage>1725</fpage>&#x2013;<lpage>39</lpage>. doi: <pub-id pub-id-type="doi">10.1111/add.13877</pub-id>, PMID: <pub-id pub-id-type="pmid">28543749</pub-id></citation></ref>
<ref id="ref8"><label>8.</label><citation citation-type="other"><person-group person-group-type="author"><collab id="coll2">UNODC</collab></person-group>. (<year>2019</year>). Treatment and care for people with drug use disorders in contact with the criminal justice system. Available at: <ext-link xlink:href="https://www.unodc.org/documents/UNODC_WHO_Alternatives_to_Conviction_or_Punishment_2018.pdf" ext-link-type="uri">https://www.unodc.org/documents/UNODC_WHO_Alternatives_to_Conviction_or_Punishment_2018.pdf</ext-link></citation></ref>
<ref id="ref9"><label>9.</label><citation citation-type="other"><person-group person-group-type="author"><name><surname>Holloway</surname><given-names>K.</given-names></name> <name><surname>Bennett</surname><given-names>T.</given-names></name> <name><surname>Farrington</surname><given-names>D.</given-names></name></person-group> (<year>2005</year>). The effectiveness of criminal justice and treatment programmes in reducing drug- related crime: a systematic review. Home Office Online Report, 1&#x2013;82. Available at: <ext-link xlink:href="https://pdfs.semanticscholar.org/c102/f6dc524df3539eb69b03f1263481bacf3efa.pdf" ext-link-type="uri">https://pdfs.semanticscholar.org/c102/f6dc524df3539eb69b03f1263481bacf3efa.pdf</ext-link></citation></ref>
<ref id="ref10"><label>10.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Perry</surname><given-names>AE</given-names></name> <name><surname>Woodhouse</surname><given-names>R</given-names></name> <name><surname>Neilson</surname><given-names>M</given-names></name> <name><surname>St James</surname><given-names>MM</given-names></name> <name><surname>Glanville</surname><given-names>J</given-names></name> <name><surname>Hewitt</surname><given-names>C</given-names></name> <etal/></person-group>. <article-title>Are non-pharmacological interventions effective in reducing drug use and criminality? A systematic and Meta-analytical review with an economic appraisal of these interventions</article-title>. <source>Int J Environ Res Public Health</source>. (<year>2016</year>) <volume>13</volume>. doi: <pub-id pub-id-type="doi">10.3390/IJERPH13100966</pub-id>, PMID: <pub-id pub-id-type="pmid">27690077</pub-id></citation></ref>
<ref id="ref11"><label>11.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Lunze</surname><given-names>K</given-names></name> <name><surname>Idrisov</surname><given-names>B</given-names></name> <name><surname>Golichenko</surname><given-names>M</given-names></name> <name><surname>Kamarulzaman</surname><given-names>A</given-names></name></person-group>. <article-title>Mandatory addiction treatment for people who use drugs: global health and human rights analysis</article-title>. <source>BMJ</source>. (<year>2016</year>) <volume>353</volume>. doi: <pub-id pub-id-type="doi">10.1136/BMJ.I2943</pub-id></citation></ref>
<ref id="ref12"><label>12.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Stevens</surname><given-names>A</given-names></name> <name><surname>Berto</surname><given-names>D</given-names></name> <name><surname>Heckmann</surname><given-names>W</given-names></name> <name><surname>Kerschl</surname><given-names>V</given-names></name> <name><surname>Oeuvray</surname><given-names>K</given-names></name> <name><surname>van Ooyen</surname><given-names>M</given-names></name> <etal/></person-group>. <article-title>Quasi-compulsory treatment of drug dependent offenders: an international literature review</article-title>. <source>Subst Use Misuse</source>. (<year>2005</year>) <volume>40</volume>:<fpage>269</fpage>&#x2013;<lpage>83</lpage>. doi: <pub-id pub-id-type="doi">10.1081/JA-200049159</pub-id></citation></ref>
<ref id="ref13"><label>13.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Werb</surname><given-names>D</given-names></name> <name><surname>Kamarulzaman</surname><given-names>A</given-names></name> <name><surname>Meacham</surname><given-names>MC</given-names></name> <name><surname>Rafful</surname><given-names>C</given-names></name> <name><surname>Fischer</surname><given-names>B</given-names></name> <name><surname>Strathdee</surname><given-names>SA</given-names></name> <etal/></person-group>. <article-title>The effectiveness of compulsory drug treatment: a systematic review</article-title>. <source>Int J Drug Policy</source>. (<year>2016</year>) <volume>28</volume>:<fpage>1</fpage>&#x2013;<lpage>9</lpage>. doi: <pub-id pub-id-type="doi">10.1016/j.drugpo.2015.12.005</pub-id></citation></ref>
<ref id="ref14"><label>14.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Bright</surname><given-names>DA</given-names></name> <name><surname>Martire</surname><given-names>KA</given-names></name></person-group>. <article-title>Does coerced treatment of substance-using offenders Lead to improvements in substance use and recidivism? A review of the treatment efficacy literature</article-title>. <source>Aust Psychol</source>. (<year>2013</year>) <volume>48</volume>:<fpage>69</fpage>&#x2013;<lpage>81</lpage>. doi: <pub-id pub-id-type="doi">10.1111/j.1742-9544.2012.00072.x</pub-id></citation></ref>
<ref id="ref15"><label>15.</label><citation citation-type="other"><person-group person-group-type="author"><name><surname>V&#x00F6;llm</surname><given-names>B.</given-names></name> <name><surname>Cerci</surname><given-names>D.</given-names></name></person-group> (<year>2021</year>). Suchtbehandlung im Ma&#x00DF;regelvollzug: Narrativer Review. Suchtmedizin. Available at: <ext-link xlink:href="https://www.ecomed-medizin.de/suchtbehandlung-im-massregelvollzug-narrativer-review" ext-link-type="uri">https://www.ecomed-medizin.de/suchtbehandlung-im-massregelvollzug-narrativer-review</ext-link></citation></ref>
<ref id="ref16"><label>16.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Jehle</surname><given-names>JM</given-names></name> <name><surname>Lewis</surname><given-names>C</given-names></name> <name><surname>Nagtegaal</surname><given-names>M</given-names></name> <name><surname>Palmowski</surname><given-names>N</given-names></name> <name><surname>Pyrcak-G&#x00F3;rowska</surname><given-names>M</given-names></name> <name><surname>van der Wolf</surname><given-names>M</given-names></name> <etal/></person-group>. <article-title>Dealing with dangerous offenders in Europe. A comparative study of provisions in England and Wales, Germany, the Netherlands, Poland and Sweden</article-title>. <source>Crim Law Forum</source>. (<year>2021</year>) <volume>32</volume>:<fpage>181</fpage>&#x2013;<lpage>245</lpage>. doi: <pub-id pub-id-type="doi">10.1007/s10609-020-09411-z</pub-id></citation></ref>
<ref id="ref17"><label>17.</label><citation citation-type="journal">&#x002A;<person-group person-group-type="author"><name><surname>Berthold</surname><given-names>D.</given-names></name> <name><surname>Riedemann</surname><given-names>C.</given-names></name></person-group> (<year>2021</year>). <article-title>Welche Patienten haben eine hinreichend konkrete Aussicht auf einen Behandlungserfolg in der Ma&#x00DF;regel nach &#x00A7; 64 StGB?</article-title> <source>Forensische Psychiatrie, Psychologie, Kriminologie</source>, <volume>15</volume>, <fpage>169</fpage>&#x2013;<lpage>178</lpage>. doi: <pub-id pub-id-type="doi">10.1007/s11757-021-00653-0</pub-id></citation></ref>
<ref id="ref18"><label>18.</label><citation citation-type="other"><person-group person-group-type="author"><collab id="coll3">Statistisches Bundesamt (Destatis)</collab></person-group>. (<year>2020</year>). Im psychiatrischen Krankenhaus und in der Entziehungsanstalt aufgrund strafrichterlicher Anordnung Untergebrachte (Ma&#x00DF;regelvollzug) im Jahr 2018.</citation></ref>
<ref id="ref19"><label>19.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>M&#x00FC;ller</surname><given-names>JL</given-names></name> <name><surname>B&#x00F6;cker</surname><given-names>FM</given-names></name> <name><surname>Eusterschulte</surname><given-names>B</given-names></name> <name><surname>Koller</surname><given-names>M</given-names></name> <name><surname>Muysers</surname><given-names>J</given-names></name> <name><surname>Pollm&#x00E4;cher</surname><given-names>T</given-names></name></person-group>. <article-title>Neuregelung des &#x00A7; 64 StGB aus psychiatrischer Sicht &#x2013; Positionspapier einer Task-Force der DGPPN</article-title>. <source>Nervenarzt</source>. (<year>2021</year>) <volume>92</volume>:<fpage>1155</fpage>&#x2013;<lpage>62</lpage>. doi: <pub-id pub-id-type="doi">10.1007/S00115-021-01109-W</pub-id></citation></ref>
<ref id="ref20"><label>20.</label><citation citation-type="journal">&#x002A;<person-group person-group-type="author"><name><surname>Quereng&#x00E4;sser</surname><given-names>J.</given-names></name> <name><surname>Bulla</surname><given-names>J.</given-names></name> <name><surname>Hoffmann</surname><given-names>K.</given-names></name> <name><surname>Ross</surname><given-names>T.</given-names></name></person-group> (<year>2018</year>). <article-title>Therapy drop-out as a predictor of re-delinquency: legal probation of substance addicted patients according to &#x00A7;64 of the German legal code</article-title>. <source>Nervenarzt</source>, <volume>89</volume>, <fpage>71</fpage>&#x2013;<lpage>77</lpage>. doi: <pub-id pub-id-type="doi">10.1007/s00115-017-0386-z</pub-id></citation></ref>
<ref id="ref21"><label>21.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Fries</surname><given-names>D</given-names></name> <name><surname>Endrass</surname><given-names>J</given-names></name> <name><surname>Ridinger</surname><given-names>M</given-names></name> <name><surname>Urbaniok</surname><given-names>F</given-names></name> <name><surname>Rossegger</surname><given-names>A</given-names></name></person-group>. <article-title>Indicators of course of inpatient therapy in offenders with substance dependency</article-title>. <source>Fortschr Neurol Psychiatr</source>. (<year>2011</year>) <volume>79</volume>:<fpage>404</fpage>&#x2013;<lpage>10</lpage>. doi: <pub-id pub-id-type="doi">10.1055/s-0029-1245962</pub-id>, PMID: <pub-id pub-id-type="pmid">21425031</pub-id></citation></ref>
<ref id="ref22"><label>22.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Quereng&#x00E4;sser</surname><given-names>J</given-names></name> <name><surname>Baur</surname><given-names>A</given-names></name></person-group>. <article-title>Predictors of the discharge mode from forensic addiction treatment: review of the determinants of success of a treatment order according to sec64 of the German criminal code (part I)</article-title>. <source>Fortschr Neurol Psychiatr</source>. (<year>2021</year>) <volume>89</volume>:<fpage>496</fpage>&#x2013;<lpage>506</lpage>. doi: <pub-id pub-id-type="doi">10.1055/a-1389-5782</pub-id>, PMID: <pub-id pub-id-type="pmid">33694136</pub-id></citation></ref>
<ref id="ref23"><label>23.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Quereng&#x00E4;sser</surname><given-names>J</given-names></name> <name><surname>Baur</surname><given-names>A</given-names></name></person-group>. <article-title>Predictors of legal probation after forensic addiction treatment: review of the determinants of success of a treatment order according to sec64 of the German criminal code-part II</article-title>. <source>Fortschr Neurol Psychiatr</source>. (<year>2021</year>) <volume>89</volume>:<fpage>507</fpage>&#x2013;<lpage>15</lpage>. doi: <pub-id pub-id-type="doi">10.1055/a-1471-3786</pub-id>, PMID: <pub-id pub-id-type="pmid">34010962</pub-id></citation></ref>
<ref id="ref24"><label>24.</label><citation citation-type="journal">&#x002A;<person-group person-group-type="author"><name><surname>Stolpmann</surname><given-names>G.</given-names></name> <name><surname>Muller</surname><given-names>J.</given-names></name></person-group> (<year>2008</year>). [<article-title>Is disulfiram (Antabus) indicated in the treatment of offenders with alcohol use disorders?</article-title>]. <source>Psychiatr Prax</source>, <volume>35</volume>, <fpage>40</fpage>&#x2013;<lpage>43</lpage>, doi: <pub-id pub-id-type="doi">10.1055/s-2006-951859</pub-id>, PMID: <pub-id pub-id-type="pmid">18297758</pub-id></citation></ref>
<ref id="ref25"><label>25.</label><citation citation-type="journal">&#x002A;<person-group person-group-type="author"><name><surname>Reiners</surname><given-names>S.</given-names></name> <name><surname>Opitz-Welke</surname><given-names>A.</given-names></name> <name><surname>Konrad</surname><given-names>N.</given-names></name> <name><surname>Voulgaris</surname><given-names>A.</given-names></name></person-group> (<year>2022</year>). <article-title>Availability of opioid agonist treatment and critical incidents in forensic clinics for dependency diseases in Germany</article-title>. <source>Front Psych</source>, <volume>13</volume>,:<fpage>961549</fpage>, doi: <pub-id pub-id-type="doi">10.3389/fpsyt.2022.961549</pub-id>, PMID: <pub-id pub-id-type="pmid">36159944</pub-id></citation></ref>
<ref id="ref26"><label>26.</label><citation citation-type="journal">&#x002A;<person-group person-group-type="author"><name><surname>Gericke</surname><given-names>B.</given-names></name> <name><surname>Kallert</surname><given-names>T. W.</given-names></name></person-group> (<year>2007</year>). <article-title>On the outcome of the treatment of mentally disordered criminal offenders (according to section 64 German penal code) suffering from addictive disorders</article-title>. <source>Psychiatr Prax</source>, <volume>34</volume>, <fpage>S218</fpage>&#x2013;<lpage>S226</lpage>. doi: <pub-id pub-id-type="doi">10.1055/s-2006-952006</pub-id>, PMID: <pub-id pub-id-type="pmid">17394114</pub-id></citation></ref>
<ref id="ref27"><label>27.</label><citation citation-type="journal">&#x002A;<person-group person-group-type="author"><name><surname>Quereng&#x00E4;sser</surname><given-names>J.</given-names></name> <name><surname>Bulla</surname><given-names>J.</given-names></name> <name><surname>Hoffmann</surname><given-names>K.</given-names></name> <name><surname>Ross</surname><given-names>T.</given-names></name></person-group> (<year>2017</year>). <article-title>Outcomepr&#x00E4;diktoren forensischer suchtbehandlungen teil II: Zum Zusammenhang von personen- und nicht personenbezogenen Faktoren mit der legalbewahrung nach entlassung aus einer unterbringung nach &#x00A7; 64 StGB</article-title>. <source>Recht &#x0026; Psychiatrie</source>, <volume>35</volume>, <fpage>139</fpage>&#x2013;<lpage>146</lpage>.</citation></ref>
<ref id="ref28"><label>28.</label><citation citation-type="other">&#x002A;<person-group person-group-type="author"><name><surname>Butz</surname><given-names>M.</given-names></name></person-group> (<year>2016</year>). Forensisch-psychiatrische Nachsorge in Bayern: Eine Untersuchung zu Deliktr&#x00FC;ckf&#x00E4;llen und Prognosefaktoren bei bedingt entlassenen Ma&#x00DF;reglelvollzugspatienten (&#x00A7;&#x00A7; 63, 64 StGB). Available at: <ext-link xlink:href="https://epub.uni-regensburg.de/34874/" ext-link-type="uri">https://epub.uni-regensburg.de/34874/</ext-link></citation></ref>
<ref id="ref29"><label>29.</label><citation citation-type="journal"><person-group person-group-type="author"><collab id="coll4">Centre for Reviews and Dissemination</collab></person-group>. <article-title>Systematic reviews: CRD&#x2019;s guidance for undertaking reviews in health care</article-title>. <source>Centre for Rev Dissemination</source>. (<year>2009</year>)</citation></ref>
<ref id="ref30"><label>30.</label><citation citation-type="other">&#x002A;<person-group person-group-type="author"><name><surname>Koch</surname><given-names>G.</given-names></name></person-group> (<year>1988</year>). <source>Katamnesen bei suchtkranken Straft&#x00E4;tern nach bedingter Entlassung aus dem Ma&#x00DF;regelvollzug gem&#x00E4;&#x00DF; &#x00A7; 64 StGB</source>.</citation></ref>
<ref id="ref31"><label>31.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Dessecker</surname><given-names>A</given-names></name></person-group>. <article-title>Suchtbehandlung als strafrechtliche Sanktion eine empirische Untersuchung zur Anordnung und Vollstreckung der Massregel nach &#x00A7; 64 StGB</article-title>. <source>Eigenverlag Kriminologische Zentralstelle</source>. (<year>1996</year>)</citation></ref>
<ref id="ref32"><label>32.</label><citation citation-type="other">&#x002A;<person-group person-group-type="author"><name><surname>Bezzel</surname><given-names>A.</given-names></name></person-group> (<year>2008</year>). <source>Therapie im Ma&#x00DF;regelvollzug - und dann? Eine Verlaufsuntersuchung an forensischen Patienten (&#x00A7;&#x00A7; 63 und 64 StGB)</source>.</citation></ref>
<ref id="ref33"><label>33.</label><citation citation-type="journal">&#x002A;<person-group person-group-type="author"><name><surname>Passow</surname><given-names>D.</given-names></name> <name><surname>Prinz</surname><given-names>E.</given-names></name> <name><surname>Maa&#x00DF;</surname><given-names>C.</given-names></name> <name><surname>Wedler</surname><given-names>K.</given-names></name> <name><surname>Bordel</surname><given-names>U.</given-names></name> <name><surname>Schl&#x00E4;fke</surname><given-names>D.</given-names></name></person-group> (<year>2016</year>). <article-title>Legalbew&#x00E4;hrung und Konsumverhalten bei Probanden der forensischen Nachsorge nach Unterbringung in einer Entziehungsanstalt (&#x00A7; 64 StGB)</article-title>. <source>Suchttherapie</source>, <volume>17</volume>, <fpage>90</fpage>&#x2013;<lpage>95</lpage>. doi: <pub-id pub-id-type="doi">10.1055/S-0041-107758</pub-id></citation></ref>
<ref id="ref34"><label>34.</label><citation citation-type="journal">&#x002A;<person-group person-group-type="author"><name><surname>Leygraf</surname><given-names>N.</given-names></name></person-group> (<year>1995</year>). <article-title>Praxis der Vollstreckung strafrechtlicher Unterbringungen gem. &#x00A7; 64 StGB</article-title>. In: Dessecker A, Egg R, editors. <source>Die strafrechtliche Unterbringung in einer Entziehungsanstalt.</source> Wiesbaden, <fpage>159</fpage>&#x2013;<lpage>162</lpage>.</citation></ref>
<ref id="ref35"><label>35.</label><citation citation-type="journal">&#x002A;<person-group person-group-type="author"><name><surname>Pfaff</surname><given-names>H.</given-names></name></person-group> (<year>1998</year>). <article-title>Ergebnisse einer prospektiven Katamneseuntersuchung nach Entziehungstherapie gem&#x00E4;&#x00DF; &#x00A7; 64 StGB bei Alkoholkranken</article-title>. <source>Nervenarzt</source>, <volume>69</volume>, <fpage>568</fpage>&#x2013;<lpage>573</lpage>, doi: <pub-id pub-id-type="doi">10.1007/s001150050313</pub-id>, PMID: <pub-id pub-id-type="pmid">9715474</pub-id></citation></ref>
<ref id="ref36"><label>36.</label><citation citation-type="journal">&#x002A;<person-group person-group-type="author"><name><surname>Bezzel</surname><given-names>A.</given-names></name></person-group> (<year>2010</year>). <article-title>K&#x00F6;nnen Patienten aus dem Ma&#x00DF;regelvollzug (&#x00A7; 64 StGB) resozialisiert werden?: Die Regensburger Katamnesestudie</article-title>. <source>Forensische Psychiatrie, Psychologie, Kriminologie</source>, <volume>4</volume>, <fpage>264</fpage>&#x2013;<lpage>268</lpage>. doi: <pub-id pub-id-type="doi">10.1007/s11757-010-0083-2</pub-id></citation></ref>
<ref id="ref37"><label>37.</label><citation citation-type="other">&#x002A;<person-group person-group-type="author"><name><surname>Hartl</surname><given-names>C.</given-names></name></person-group> (<year>2012</year>). Wie erfolgreich ist die Behandlung im Ma&#x00DF;regelvollzug nach &#x00A7;&#x00A7; 63 und 64 StGB? Eine Untersuchung anhand verschiedener Erfolgsma&#x00DF;e. Available at: <ext-link xlink:href="https://epub.uni-regensburg.de/27198/1/dissertationwinCH.pdf" ext-link-type="uri">https://epub.uni-regensburg.de/27198/1/dissertationwinCH.pdf</ext-link></citation></ref>
<ref id="ref38"><label>38.</label><citation citation-type="journal">&#x002A;<person-group person-group-type="author"><name><surname>Bezzel</surname><given-names>A.</given-names></name></person-group> (<year>2013</year>). <article-title>Der Blick in den Spiegel... Standardisierte Erhebung der Ergebnisqualit&#x00E4;t im Bayerischen Ma&#x00DF;regelvollzug</article-title>. <source>Recht &#x0026; Psychiatrie</source>, <volume>31</volume>, <fpage>123</fpage>&#x2013;<lpage>128</lpage>.</citation></ref>
<ref id="ref39"><label>39.</label><citation citation-type="journal">&#x002A;<person-group person-group-type="author"><name><surname>Dudeck</surname><given-names>M.</given-names></name> <name><surname>Franke</surname><given-names>I.</given-names></name> <name><surname>Bezzel</surname><given-names>A.</given-names></name> <name><surname>Otte</surname><given-names>S.</given-names></name> <name><surname>Ormanns</surname><given-names>N.</given-names></name> <name><surname>Nigel</surname><given-names>S.</given-names></name> <etal/></person-group>. (<year>2018</year>). <article-title>Who benefits from forensic psychiatric treatment? Results of a Catamnestic study in Swabia</article-title>. <source>Psychiatr Prax</source>, <volume>45</volume>, <fpage>375</fpage>&#x2013;<lpage>382</lpage>. doi: <pub-id pub-id-type="doi">10.1055/a-0579-9649</pub-id>, PMID: <pub-id pub-id-type="pmid">29665607</pub-id></citation></ref>
<ref id="ref40"><label>40.</label><citation citation-type="journal">&#x002A;<person-group person-group-type="author"><name><surname>Franke</surname><given-names>I.</given-names></name> <name><surname>Rothe</surname><given-names>P.</given-names></name> <name><surname>Dudeck</surname><given-names>M.</given-names></name> <name><surname>Bezzel</surname><given-names>A.</given-names></name> <name><surname>Klein</surname><given-names>V.</given-names></name> <name><surname>Ormanns</surname><given-names>N.</given-names></name> <etal/></person-group>. (<year>2020</year>). <article-title>Comparison of outcome in men and women after treatment in psychiatric security hospitals in Germany</article-title>. <source>Behav Sci Law</source>, <volume>38</volume>, <fpage>456</fpage>&#x2013;<lpage>470</lpage>. doi: <pub-id pub-id-type="doi">10.1002/BSL.2483</pub-id>, PMID: <pub-id pub-id-type="pmid">32844491</pub-id></citation></ref>
<ref id="ref41"><label>41.</label><citation citation-type="journal">&#x002A;<person-group person-group-type="author"><name><surname>Schalast</surname><given-names>N.</given-names></name></person-group> (<year>1994</year>). <article-title>Unterbringung in der Entziehungsanstalt: Probleme der Behandlung alkoholabh&#x00E4;ngiger Straft&#x00E4;ter. Argumente f&#x00FC;r eine Vollzugsl&#x00F6;sung</article-title>. <source>Recht &#x0026; Psychiatrie</source>, <volume>12</volume>, <fpage>2</fpage>&#x2013;<lpage>10</lpage>.</citation></ref>
<ref id="ref42"><label>42.</label><citation citation-type="journal">&#x002A;<person-group person-group-type="author"><name><surname>Schalast</surname><given-names>N.</given-names></name></person-group> (<year>2000</year>). <article-title>Treatment of addicted offenders in hospital order clinics in Germany: the problem of patients&#x2019; relapsing in treatment</article-title>. <source>Sucht</source>, <volume>46</volume>, <fpage>111</fpage>&#x2013;<lpage>120</lpage>. doi: <pub-id pub-id-type="doi">10.1024/suc.2000.46.2.111</pub-id></citation></ref>
<ref id="ref43"><label>43.</label><citation citation-type="journal">&#x002A;<person-group person-group-type="author"><name><surname>Schalast</surname><given-names>N.</given-names></name></person-group> (<year>2000</year>). <article-title>Zur Frage der Behandlungsmotivation bei Patienten des Ma&#x00DF;regelvollzugs gem&#x00E4;&#x00DF; &#x00A7; 64 StGB</article-title>. <source>Psychiatr Prax.</source> <volume>27</volume>, <fpage>270</fpage>&#x2013;<lpage>276</lpage>, PMID: <pub-id pub-id-type="pmid">11050732</pub-id></citation></ref>
<ref id="ref44"><label>44.</label><citation citation-type="journal">&#x002A;<person-group person-group-type="author"><name><surname>Quereng&#x00E4;sser</surname><given-names>J.</given-names></name> <name><surname>Bulla</surname><given-names>J.</given-names></name> <name><surname>Hoffmann</surname><given-names>K.</given-names></name> <name><surname>Ross</surname><given-names>T.</given-names></name></person-group> (<year>2017</year>). <article-title>Predictors of re-offending in German substance-abusers in legal detention: a prospective population-based cohort study</article-title>. <source>J Forensic Psychiatry Psychol</source>, <volume>29</volume>, <fpage>337</fpage>&#x2013;<lpage>350</lpage>. doi: <pub-id pub-id-type="doi">10.1080/14789949.2017.1387926</pub-id></citation></ref>
<ref id="ref45"><label>45.</label><citation citation-type="journal">&#x002A;<person-group person-group-type="author"><name><surname>Frey</surname><given-names>M.</given-names></name> <name><surname>Leygraf</surname><given-names>N.</given-names></name> <name><surname>Schalast</surname><given-names>N.</given-names></name></person-group> (<year>2019</year>). <article-title>ADHD as a problem and a therapeutic focus in forensic addiction treatment</article-title>. <source>Forensische Psychiatrie, Psychologie, Kriminologie</source>, <volume>13</volume>, <fpage>239</fpage>&#x2013;<lpage>250</lpage>, doi: <pub-id pub-id-type="doi">10.1007/s11757-019-00545-4</pub-id></citation></ref>
<ref id="ref46"><label>46.</label><citation citation-type="other">&#x002A;<person-group person-group-type="author"><name><surname>Quereng&#x00E4;sser</surname><given-names>J.</given-names></name></person-group> (<year>2011</year>). Zusammenh&#x00E4;nge zwischen Redebeitr&#x00E4;gen und therapeutischen Erfolgsparametern in forensischer Gruppentherapie&#x2013;eine explorative Studie. Available at: <ext-link xlink:href="https://www.researchgate.net/profile/Jan-Querengaesser/publication/284731289_Zusammenhange_zwischen_Redebeitragen_und_therapeutischen_Erfolgsparametern_in_forensischer_Gruppentherapie_-_eine_explorative_Studie/links/5ee9bab5458515814a653770/Zusammenhaenge" ext-link-type="uri">https://www.researchgate.net/profile/Jan-Querengaesser/publication/284731289_Zusammenhange_zwischen_Redebeitragen_und_therapeutischen_Erfolgsparametern_in_forensischer_Gruppentherapie_-_eine_explorative_Studie/links/5ee9bab5458515814a653770/Zusammenhaenge</ext-link></citation></ref>
<ref id="ref47"><label>47.</label><citation citation-type="journal">&#x002A;<person-group person-group-type="author"><name><surname>Berger</surname><given-names>J.</given-names></name> <name><surname>Scheurer</surname><given-names>H.</given-names></name> <name><surname>Honecker</surname><given-names>Y.</given-names></name> <name><surname>Andritsch</surname><given-names>F.</given-names></name> <name><surname>Six</surname><given-names>A. T. I.</given-names></name></person-group> (<year>1999</year>). <article-title>Alcohol and drug addicted delinquents - identification of prognostically favourable and unfavourable patient groups hospitalised in accordance with 64 German penal code</article-title>. <source>Fortschritte der Neurologie Psychiatrie</source>, <volume>67</volume>, <fpage>502</fpage>&#x2013;<lpage>508</lpage>. doi: <pub-id pub-id-type="doi">10.1055/s-2007-995227</pub-id>, PMID: <pub-id pub-id-type="pmid">10598333</pub-id></citation></ref>
<ref id="ref48"><label>48.</label><citation citation-type="other">&#x002A;<person-group person-group-type="author"><name><surname>Schalast</surname><given-names>N.</given-names></name> <name><surname>Mushoff</surname><given-names>S.</given-names></name> <name><surname>Demmerling</surname><given-names>R.</given-names></name></person-group> (<year>2004</year>). Alkoholabh&#x00E4;ngige Patienten im Ma&#x00DF;regelvollzug gem&#x00E4;&#x00DF; &#x00A7; 64 StGB. Available at: <ext-link xlink:href="https://www.uni-due.de/imperia/md/content/rke-forensik/projekte/projektberichtpar64alkoholpatienten2004.pdf" ext-link-type="uri">https://www.uni-due.de/imperia/md/content/rke-forensik/projekte/projektberichtpar64alkoholpatienten2004.pdf</ext-link></citation></ref>
<ref id="ref49"><label>49.</label><citation citation-type="other">&#x002A;<person-group person-group-type="author"><name><surname>Schalast</surname><given-names>N.</given-names></name></person-group> &#x0026; <person-group person-group-type="author"><name><surname>Kosters</surname><given-names>C</given-names></name></person-group>. (<year>2008</year>). Evaluation des Ma&#x00DF;regelvollzugs gem&#x00E4;&#x00DF; &#x00A7; 64 StGB - &#x201C;Machbarkeitsstudie&#x201D; Available at: <ext-link xlink:href="https://www.uni-due.de/imperia/md/content/rke-forensik/projekte/machbarkeitsstudieevaluationpar642008.pdf" ext-link-type="uri">https://www.uni-due.de/imperia/md/content/rke-forensik/projekte/machbarkeitsstudieevaluationpar642008.pdf</ext-link></citation></ref>
<ref id="ref50"><label>50.</label><citation citation-type="journal">&#x002A;<person-group person-group-type="author"><name><surname>Schalast</surname><given-names>N.</given-names></name> <name><surname>K&#x00F6;sters</surname><given-names>C.</given-names></name> <name><surname>Demmerling</surname><given-names>R.</given-names></name> <name><surname>Mushoff</surname><given-names>S.</given-names></name></person-group> (<year>2011</year>). <article-title>Drei prognostisch und therapeutisch relevante Gruppen alkoholabh&#x00E4; ngiger Patienten im Ma&#x00DF;regelvollzug gem&#x00E4;&#x00DF; &#x00A7; 64 StGB 1</article-title>. <source>Psychiatr Prax</source>, <volume>38</volume>, <fpage>31</fpage>&#x2013;<lpage>37</lpage>. doi: <pub-id pub-id-type="doi">10.1055/s-0030-1248602</pub-id>, PMID: <pub-id pub-id-type="pmid">20972951</pub-id></citation></ref>
<ref id="ref51"><label>51.</label><citation citation-type="journal">&#x002A;<person-group person-group-type="author"><name><surname>Schalast</surname><given-names>N.</given-names></name> <name><surname>K&#x00F6;sters</surname><given-names>C.</given-names></name> <name><surname>Mushoff</surname><given-names>S.</given-names></name> <name><surname>Demmerling</surname><given-names>R.</given-names></name></person-group> (<year>2009</year>). <article-title>Zur Prognose des Behandlungsverlaufs bei strafrechtlicher Unterbringung in der Entziehungsanstalt</article-title>. <source>Sucht</source>, <volume>55</volume>, <fpage>19</fpage>&#x2013;<lpage>29</lpage>. doi: <pub-id pub-id-type="doi">10.1024/2009.01.04</pub-id></citation></ref>
<ref id="ref52"><label>52.</label><citation citation-type="other">&#x002A;<person-group person-group-type="author"><name><surname>Kemper</surname><given-names>A.</given-names></name></person-group> (<year>2009</year>). <source>Die Unterbringung in der Entziehungsanstalt zwischen Fehleinweisung und Fehlkonstruktion Analyse des &#x00A7; 64 StGB in der nordrhein-westf&#x00E4;lischen Praxis.</source> Universit&#x00E4;t Bremen.</citation></ref>
<ref id="ref53"><label>53.</label><citation citation-type="journal">&#x002A;<person-group person-group-type="author"><name><surname>Rotermund</surname><given-names>P.</given-names></name> <name><surname>Berger</surname><given-names>K.</given-names></name> <name><surname>Lehmann</surname><given-names>J.</given-names></name></person-group> (<year>2013</year>). <article-title>The prognostic validity of PCL-R and custodial addiction treatment (&#x00A7; 64 of the German criminal code)</article-title>. <source>Monatsschrift f&#x00FC;r Kriminologie und Strafrechtsreform</source>, <volume>96</volume>, <fpage>314</fpage>&#x2013;<lpage>324</lpage>. doi: <pub-id pub-id-type="doi">10.1515/mks-2013-960403</pub-id></citation></ref>
<ref id="ref54"><label>54.</label><citation citation-type="journal">&#x002A;<person-group person-group-type="author"><name><surname>Schalast</surname><given-names>N.</given-names></name> <name><surname>Steffen</surname><given-names>M.</given-names></name> <name><surname>Boateng</surname><given-names>S.</given-names></name></person-group> (<year>2013</year>). <article-title>The Essen evaluation of treatment in forensic addiction rehabilitation centers: an interim report</article-title>. <source>Forensische Psychiatrie, Psychologie, Kriminologie</source>, <volume>7</volume>, <fpage>94</fpage>&#x2013;<lpage>104</lpage>. doi: <pub-id pub-id-type="doi">10.1007/s11757-013-0208-5</pub-id></citation></ref>
<ref id="ref55"><label>55.</label><citation citation-type="journal">&#x002A;<person-group person-group-type="author"><name><surname>Hartl</surname><given-names>C.</given-names></name> <name><surname>Schlauderer</surname><given-names>R.</given-names></name> <name><surname>Schl&#x00F6;gl</surname><given-names>C.</given-names></name> <name><surname>Mache</surname><given-names>W.</given-names></name></person-group> (<year>2015</year>). <article-title>How effective is the treatment of substance-addicted offenders (&#x00A7; 64 German criminal code)?: a comparison between completed and discontinued therapy</article-title>. <source>Monatsschrift Fur Kriminologie Und Strafrechtsreform</source>, <volume>98</volume>, <fpage>513</fpage>&#x2013;<lpage>526</lpage>. doi: <pub-id pub-id-type="doi">10.1515/mks-2015-980603</pub-id></citation></ref>
<ref id="ref56"><label>56.</label><citation citation-type="journal">&#x002A;<person-group person-group-type="author"><name><surname>Querengaesser</surname><given-names>J.</given-names></name> <name><surname>Bulla</surname><given-names>J.</given-names></name> <name><surname>Hoffmann</surname><given-names>K.</given-names></name> <name><surname>Ross</surname><given-names>T.</given-names></name></person-group> (<year>2015</year>). <article-title>Outcome-related predictors of forensic substance abuse treatment an integration of personal and non-personal variables predicting treatment</article-title>. <source>Recht &#x0026; Psychiatrie</source>, <volume>33</volume>, <fpage>34</fpage>&#x2013;<lpage>41</lpage>.</citation></ref>
<ref id="ref60"><label>57.</label><citation citation-type="other">&#x002A;<person-group person-group-type="author"><name><surname>Schalast</surname><given-names>N.</given-names></name> <name><surname>Frey</surname><given-names>M.</given-names></name> <name><surname>Boateng</surname><given-names>S.</given-names></name> <name><surname>Massau</surname><given-names>C.</given-names></name></person-group> (<year>2016</year>). Ertrag der Unterbringung in einer Entziehungsanstalt gem&#x00E4;&#x00DF; &#x00A7; 64 StGB: Evaluationsstudie zum Vergleich von Ma&#x00DF;regelvollzug und Strafvollzug bei suchtkranken Straft&#x00E4;tern. Available at: <ext-link xlink:href="https://www.uni-due.de/imperia/md/content/rke-forensik/projekte/projektzwischenbericht_iii_2016.pdf" ext-link-type="uri">https://www.uni-due.de/imperia/md/content/rke-forensik/projekte/projektzwischenbericht_iii_2016.pdf</ext-link></citation></ref>
<ref id="ref57"><label>58.</label><citation citation-type="journal">&#x002A;<person-group person-group-type="author"><name><surname>Rosch</surname><given-names>I.</given-names></name> <name><surname>Lachmanski</surname><given-names>A.</given-names></name> <name><surname>Herich</surname><given-names>L.</given-names></name> <name><surname>Taddey</surname><given-names>S.</given-names></name> <name><surname>Lange</surname><given-names>M.</given-names></name> <name><surname>Wolf</surname><given-names>M.</given-names></name> <etal/></person-group>. (<year>2016</year>). <article-title>Patientengruppen mit unterschiedlichem Risikoprofil f&#x00FC;r eine vorzeitige Erledigung des Ma&#x03B2;regelvollzugs (&#x00A7; 64 StGB)</article-title>. <source>Psychiatr Prax</source>, <volume>43</volume>, <fpage>25</fpage>&#x2013;<lpage>31</lpage>. doi: <pub-id pub-id-type="doi">10.1055/S-0034-1370305/ID/JR527-41</pub-id>, PMID: <pub-id pub-id-type="pmid">25180679</pub-id></citation></ref>
<ref id="ref58"><label>59.</label><citation citation-type="journal">&#x002A;<person-group person-group-type="author"><name><surname>Ross</surname><given-names>T.</given-names></name> <name><surname>Ade</surname><given-names>J.</given-names></name> <name><surname>Van Oorsouw</surname><given-names>K.</given-names></name></person-group> (<year>2020</year>). <article-title>Rauchen und Nichtrauchen in forensisch-psychiatrischen Settings (&#x00A7; 64 StGB). Gibt es Zusammenh&#x00E4;nge mit dem Outcome?</article-title>. <source>Forensische Psychiatrie Und Psychotherapie</source>, <volume>27</volume>, <fpage>98</fpage>&#x2013;<lpage>109</lpage>.</citation></ref>
<ref id="ref59"><label>60.</label><citation citation-type="journal">&#x002A;<person-group person-group-type="author"><name><surname>Lutz</surname><given-names>M.</given-names></name> <name><surname>Quereng&#x00E4;sser</surname><given-names>J.</given-names></name> <name><surname>Bezzel</surname><given-names>A.</given-names></name> <name><surname>Schl&#x00F6;gl</surname><given-names>C.</given-names></name> <name><surname>Streb</surname><given-names>J.</given-names></name> <name><surname>Dudeck</surname><given-names>M</given-names></name></person-group>. (<year>2023</year>). <article-title>Treatment outcome of migrants and non-migrants in forensic psychiatry. A retrospective case control study using Bavarian data from 2010 to 2019</article-title>. <source>Psychiatr Prax</source>. <volume>50</volume>, <fpage>250</fpage>&#x2013;<lpage>55</lpage>. doi: <pub-id pub-id-type="doi">10.1055/a-2009-1360</pub-id></citation></ref>
<ref id="ref64"><label>61.</label><citation citation-type="other">&#x002A;<person-group person-group-type="author"><name><surname>Seibold</surname><given-names>V. J.</given-names></name></person-group> (<year>2017</year>). Pr&#x00E4;diktoren f&#x00FC;r Therapieerfolg bei suchtkranken Straft&#x00E4;tern im Ma&#x00DF;regelvollzug. Available at: <ext-link xlink:href="https://oparu.uni-ulm.de/xmlui/handle/123456789/4451" ext-link-type="uri">https://oparu.uni-ulm.de/xmlui/handle/123456789/4451</ext-link></citation></ref>
<ref id="ref62"><label>62.</label><citation citation-type="journal">&#x002A;<person-group person-group-type="author"><name><surname>Fontao</surname><given-names>M. I.</given-names></name> <name><surname>Massau</surname><given-names>C.</given-names></name> <name><surname>Hoffmann</surname><given-names>K.</given-names></name> <name><surname>Ross</surname><given-names>T.</given-names></name></person-group> (<year>2012</year>). <article-title>Therapeutische Allianz and therapeutische Prozesse in einer Gruppentherapie mit substanzabh&#x00E4;ngigen Straft&#x00E4;tern</article-title>. <source>Gruppenpsychotherapie und Gruppendynamik</source>, <volume>48</volume>, <fpage>173</fpage>&#x2013;<lpage>197</lpage>. doi: <pub-id pub-id-type="doi">10.13109/grup.2012.48.2.173</pub-id></citation></ref>
<ref id="ref61"><label>63.</label><citation citation-type="book">&#x002A;<person-group person-group-type="author"><name><surname>Berger</surname><given-names>K.</given-names></name></person-group> (<year>2010</year>). <article-title>Erfassung von forensischen Patienten (&#x00A7; 64 StGB) unter besonderer Ber&#x00FC;cksichtigung der Psychopathy Checklist nach Hare (PCL-R)</article-title>. <source>Institut F&#x00FC;r Forensische Psychiatrie Der Medizinischen Fakult&#x00E4;t Charit&#x00E9;</source>. <publisher-loc>Berlin</publisher-loc>: <publisher-name>Universit&#x00E4;tsmedizin</publisher-name>, <fpage>1</fpage>&#x2013;<lpage>82</lpage>.</citation></ref>
<ref id="ref63"><label>64.</label><citation citation-type="journal">&#x002A;<person-group person-group-type="author"><name><surname>Quereng&#x00E4;sser</surname><given-names>J.</given-names></name> <name><surname>Ross</surname><given-names>T.</given-names></name> <name><surname>Hoffmann</surname><given-names>K.</given-names></name></person-group> (<year>2013</year>). <article-title>What precedes treatment failure? A preliminary study on the reasons for premature termination of forensic treatments according to section 64 of the German legal code</article-title>. <source>Forensische Psychiatr Psychother-Werkstattschriften</source>, <volume>20</volume>, <fpage>148</fpage>&#x2013;<lpage>169</lpage>.</citation></ref>
<ref id="ref65"><label>65.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Seifert</surname><given-names>D</given-names></name> <name><surname>Leygraf</surname><given-names>N</given-names></name></person-group>. <article-title>Drogenabh&#x00E4;ngige Straft&#x00E4;ter im Ma&#x00DF;regelvollzug: Ergebnisse einer Querschnittserhebung</article-title>. <source>Nervenarzt</source>. (<year>1999</year>) <volume>70</volume>:<fpage>450</fpage>&#x2013;<lpage>6</lpage>. doi: <pub-id pub-id-type="doi">10.1007/s001150050461</pub-id>, PMID: <pub-id pub-id-type="pmid">10407841</pub-id></citation></ref>
<ref id="ref66"><label>66.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Seifert</surname><given-names>D</given-names></name> <name><surname>Klink</surname><given-names>M</given-names></name> <name><surname>Landwehr</surname><given-names>S</given-names></name></person-group>. <article-title>R&#x00FC;ckfalldaten behandelter Patienten im Ma&#x00DF;regelvollzug nach &#x00A7; 63 StGB</article-title>. <source>Forensische Psychiatrie, Psychologie, Kriminologie</source>. (<year>2018</year>) <volume>12</volume>:<fpage>136</fpage>&#x2013;<lpage>48</lpage>. doi: <pub-id pub-id-type="doi">10.1007/s11757-018-0471-6</pub-id></citation></ref>
<ref id="ref67"><label>67.</label><citation citation-type="other"><person-group person-group-type="author"><name><surname>Jehle</surname><given-names>J Martin</given-names></name></person-group>. (<year>2015</year>). Criminal justice in Germany facts and figures. Forum Vlg Godesberg. Available at: <ext-link xlink:href="https://books.google.com/books/about/Criminal_Justice_in_Germany.html?id=Z7ZlCQAAQBAJ" ext-link-type="uri">https://books.google.com/books/about/Criminal_Justice_in_Germany.html?id=Z7ZlCQAAQBAJ</ext-link></citation></ref>
<ref id="ref68"><label>68.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Kaskela</surname><given-names>T</given-names></name> <name><surname>Pitk&#x00E4;nen</surname><given-names>T</given-names></name></person-group>. <article-title>Association between the discontinuation of substance use inpatient treatment and the risk of committing a crime leading to imprisonment: a Finnish registry-based 5-year follow-up</article-title>. <source>Crim Behav Ment Health</source>. (<year>2021</year>) <volume>31</volume>:<fpage>171</fpage>&#x2013;<lpage>82</lpage>. doi: <pub-id pub-id-type="doi">10.1002/cbm.2198</pub-id>, PMID: <pub-id pub-id-type="pmid">33950557</pub-id></citation></ref>
<ref id="ref69"><label>69.</label><citation citation-type="journal">&#x002A;<person-group person-group-type="author"><name><surname>Quereng&#x00E4;sser</surname><given-names>J.</given-names></name> <name><surname>Bulla</surname><given-names>J.</given-names></name> <name><surname>Mielke</surname><given-names>R.</given-names></name> <name><surname>Hoffmann</surname><given-names>K.</given-names></name> <name><surname>Ross</surname><given-names>T.</given-names></name></person-group> (<year>2016</year>). <article-title>Patienten- und Therapeutensicht auf Abbruchgr&#x00FC;nde bei Therapien nach &#x00A7; 64 StGB - Kurztitel: Abbruchgr&#x00FC;nde f&#x00FC;r Therapien nach &#x00A7; 64 StGB</article-title>. <source>Sucht</source>, <volume>62</volume>, <fpage>225</fpage>&#x2013;<lpage>231</lpage>. doi: <pub-id pub-id-type="doi">10.1024/0939-5911/a000433</pub-id></citation></ref>
<ref id="ref70"><label>70.</label><citation citation-type="journal">&#x002A;<person-group person-group-type="author"><name><surname>Quereng&#x00E4;sser</surname><given-names>J.</given-names></name> <name><surname>Hoffmann</surname><given-names>K.</given-names></name> <name><surname>Ross</surname><given-names>T.</given-names></name></person-group> (<year>2014</year>). <article-title>Die Meinung der Anderen! - Wie die Haltung wichtiger Bezugspersonen den Verlauf einer Entziehungsma&#x00DF;regel beeinflusst</article-title>. <source>Forensische Psychiatrie Und Psychotherapie</source>, <volume>21</volume>, <fpage>287</fpage>&#x2013;<lpage>301</lpage>.</citation></ref>
<ref id="ref71"><label>71.</label><citation citation-type="book">&#x002A;<person-group person-group-type="author"><name><surname>Ross</surname><given-names>T.</given-names></name> <name><surname>Fontao</surname><given-names>M. I.</given-names></name> <name><surname>Opitz-Welke</surname><given-names>A.</given-names></name> <name><surname>Bulla</surname><given-names>J.</given-names></name></person-group> (<year>2022</year>). <article-title>Ethnic minority forensic patients in the German Federal State of Baden-W&#x00FC;rttemberg</article-title>&#x2019;. in: Eds <person-group person-group-type="editor"><name><surname>Tomlin</surname> <given-names>J.</given-names></name> <name><surname>V&#x00F6;llm</surname> <given-names>B</given-names></name></person-group>.: <source>Diversity and marginalisation in forensic mental health care</source>. <publisher-name>Routledge. London</publisher-name>, <publisher-loc>UK</publisher-loc>.</citation></ref>
<ref id="ref72"><label>72.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Neumann</surname><given-names>B</given-names></name> <name><surname>Ross</surname><given-names>T</given-names></name> <name><surname>Opitz-Welke</surname><given-names>A</given-names></name></person-group>. <article-title>Foreign National Patients in German prison psychiatry</article-title>. <source>Front Psych</source>. (<year>2020</year>) <volume>10</volume>. doi: <pub-id pub-id-type="doi">10.3389/fpsyt.2019.00988</pub-id>, PMID: <pub-id pub-id-type="pmid">32116816</pub-id></citation></ref>
<ref id="ref73"><label>73.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Sinha</surname><given-names>R</given-names></name></person-group>. <article-title>New findings on biological factors predicting addiction relapse vulnerability</article-title>. <source>Curr Psychiatry Rep</source>. (<year>2011</year>) <volume>13</volume>:<fpage>398</fpage>&#x2013;<lpage>405</lpage>. doi: <pub-id pub-id-type="doi">10.1007/s11920-011-0224-0</pub-id>, PMID: <pub-id pub-id-type="pmid">21792580</pub-id></citation></ref>
<ref id="ref74"><label>74.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Kelly</surname><given-names>JF</given-names></name> <name><surname>Finney</surname><given-names>JW</given-names></name> <name><surname>Moos</surname><given-names>R</given-names></name></person-group>. <article-title>Substance use disorder patients who are mandated to treatment: characteristics, treatment process, and 1- and 5-year outcomes</article-title>. <source>J Subst Abuse Treat</source>. (<year>2005</year>) <volume>28</volume>:<fpage>213</fpage>&#x2013;<lpage>23</lpage>. doi: <pub-id pub-id-type="doi">10.1016/J.JSAT.2004.10.014</pub-id>, PMID: <pub-id pub-id-type="pmid">15857721</pub-id></citation></ref>
<ref id="ref75"><label>75.</label><citation citation-type="other"><person-group person-group-type="author"><name><surname>Drennan</surname><given-names>G.</given-names></name> <name><surname>Wooldridge</surname><given-names>J.</given-names></name> <name><surname>Aiyegbusi</surname><given-names>A.</given-names></name> <name><surname>Alred</surname><given-names>D.</given-names></name> <name><surname>Ayres</surname><given-names>J.</given-names></name> <name><surname>Barker</surname><given-names>R.</given-names></name> <etal/></person-group>. (<year>2014</year>). Making recovery a reality in forensic settings. Available at: <ext-link xlink:href="https://www.nhsconfed.org/-/media/Confederation/Files/Publications/Documents/making-recovery-reality-forensic-settings.pdf" ext-link-type="uri">https://www.nhsconfed.org/-/media/Confederation/Files/Publications/Documents/making-recovery-reality-forensic-settings.pdf</ext-link></citation></ref>
<ref id="ref76"><label>76.</label><citation citation-type="other"><person-group person-group-type="author"><name><surname>Robb&#x00E9;</surname><given-names>M. De V</given-names></name></person-group>. (<year>2014</year>). Protective factors validation of the structured assessment of protective factors for violence risk in forensic psychiatry. Available at: <ext-link xlink:href="http://repository.ubn.ru.nl/bitstream/handle/2066/126440/126440.pdf" ext-link-type="uri">http://repository.ubn.ru.nl/bitstream/handle/2066/126440/126440.pdf</ext-link></citation></ref>
<ref id="ref77"><label>77.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>V&#x00F6;llm</surname><given-names>B</given-names></name> <name><surname>Clarke</surname><given-names>M</given-names></name> <name><surname>Herrando</surname><given-names>VT</given-names></name> <name><surname>Sepp&#x00E4;nen</surname><given-names>AO</given-names></name> <name><surname>Gosek</surname><given-names>P</given-names></name> <name><surname>Heitzman</surname><given-names>J</given-names></name> <etal/></person-group>. <article-title>European psychiatric association (EPA) guidance on forensic psychiatry: evidence based assessment and treatment of mentally disordered offenders</article-title>. <source>Eur Psychiatry</source>. (<year>2018</year>) <volume>51</volume>:<fpage>58</fpage>&#x2013;<lpage>73</lpage>. doi: <pub-id pub-id-type="doi">10.1016/j.eurpsy.2017.12.007</pub-id>, PMID: <pub-id pub-id-type="pmid">29571072</pub-id></citation></ref>
<ref id="ref78"><label>78.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Ward</surname><given-names>T</given-names></name> <name><surname>Brown</surname><given-names>M</given-names></name></person-group>. <article-title>The good lives model and conceptual issues in offender rehabilitation</article-title>. <source>Psychol Crime Law</source>. (<year>2004</year>) <volume>10</volume>:<fpage>243</fpage>&#x2013;<lpage>57</lpage>. doi: <pub-id pub-id-type="doi">10.1080/10683160410001662744</pub-id></citation></ref>
<ref id="ref79"><label>79.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Markham</surname><given-names>S</given-names></name></person-group>. <article-title>Collaborative risk assessment in secure and forensic mental health settings in the UK</article-title>. <source>General Psychiatry</source>. (<year>2020</year>) <volume>33</volume>:<fpage>e100291</fpage>. doi: <pub-id pub-id-type="doi">10.1136/GPSYCH-2020-100291</pub-id>, PMID: <pub-id pub-id-type="pmid">32875275</pub-id></citation></ref>
<ref id="ref80"><label>80.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Simpson</surname><given-names>AIF</given-names></name> <name><surname>Penney</surname><given-names>SR</given-names></name></person-group>. <article-title>Recovery and forensic care: recent advances and future directions</article-title>. <source>Crim Behav Ment Health</source>. (<year>2018</year>) <volume>28</volume>:<fpage>383</fpage>&#x2013;<lpage>9</lpage>. doi: <pub-id pub-id-type="doi">10.1002/cbm.2090</pub-id></citation></ref>
<ref id="ref81"><label>81.</label><citation citation-type="other"><person-group person-group-type="author"><name><surname>Berthold</surname><given-names>D.</given-names></name> <name><surname>Riedemann</surname><given-names>C.</given-names></name></person-group> (<year>2019</year>). <source>Deutschlandweite Stichtagserhebung im Ma&#x00DF;regelvollzug gem. &#x00A7; 64 StGB: Auswertung der Daten 2018</source>.</citation></ref>
<ref id="ref82"><label>82.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Schalast</surname><given-names>N</given-names></name> <name><surname>Redies</surname><given-names>M</given-names></name> <name><surname>Collins</surname><given-names>M</given-names></name> <name><surname>Stacey</surname><given-names>J</given-names></name> <name><surname>Howells</surname><given-names>K</given-names></name></person-group>. <article-title>EssenCES, a short questionnaire for assessing the social climate of forensic psychiatric wards</article-title>. <source>Crim Behav Ment Health</source>. (<year>2008</year>) <volume>18</volume>:<fpage>49</fpage>&#x2013;<lpage>58</lpage>. doi: <pub-id pub-id-type="doi">10.1002/cbm.677</pub-id>, PMID: <pub-id pub-id-type="pmid">18229876</pub-id></citation></ref>
</ref-list>
</back>
</article>