AUTHOR=Gui Zhen , Wang Yue-Ying , Li Jia-Xin , Li Xiao-Hong , Su Zhaohui , Cheung Teris , Lok Ka-In , Ungvari Gabor S. , Ng Chee H. , Zhang Qinge , Xiang Yu-Tao TITLE=Prevalence of poor sleep quality in COVID-19 patients: a systematic review and meta-analysis JOURNAL=Frontiers in Psychiatry VOLUME=Volume 14 - 2023 YEAR=2024 URL=https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2023.1272812 DOI=10.3389/fpsyt.2023.1272812 ISSN=1664-0640 ABSTRACT=Objective: The coronavirus disease and the public health responses were associated with a huge health burden, which could influence sleep quality. This meta-analysis and systematic review examined the prevalence of poor sleep quality in COVID-19 patients.Methods: PubMed, Web of Science, Embase, and PsycINFO were systematically searched from their respective inception to October 27, 2022. Prevalence rates of poor sleep were synthesized using a random effects model.Results: Totally, 24 epidemiological and 12 comparative studies with 8,146 COVID-19 patients and 5,787 healthy controls were included. The pooled prevalence of poor sleep quality based on the included studies was 65.0% (95%CI: 59.56%-70.44%, I 2 = 97.6%). COVID-19 patients had a higher risk of poor sleep quality compared to healthy controls (OR=1.73, 95% CI: 1.30-2.30, p < 0.01, I 2 = 78.1%) based on the 12 comparative studies. Subgroup analysis revealed that COVID-19 patients in low-income countries (P = 0.011) and in studies using a lower Pittsburgh Sleep Quality Index score cut-off (P < 0.001) were more likely to have poor sleep quality. Meta-regression analyses revealed that being female (P=0.044), older (P<0.001) and married (P=0.009) were significantly correlated with a higher risk of poor sleep quality in COVID-19 patients.Poor sleep quality was found to be very common in COVID-19 patients. Considering the negative effects of poor sleep quality on daily life, sleep quality should be routinely assessed and appropriately addressed in COVID-19 patients.