AUTHOR=Kibralew Getasew , Demilew Demeke , Koye Selam , Yitayih Sewbesew , Kelebie Mulualem , Melkam Mamaru , Tadesse Gebresilassie , Fentahun Setegn , Nakie Girum , Wassie Yilkal Abebaw , Amare Tadele TITLE=Prevalence and associated factors of premenstrual dysphoric disorder among high school students in Finote Selam town, northwest Ethiopia JOURNAL=Frontiers in Psychiatry VOLUME=Volume 15 - 2024 YEAR=2024 URL=https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2024.1362118 DOI=10.3389/fpsyt.2024.1362118 ISSN=1664-0640 ABSTRACT=Background: Premenstrual dysphoric disorder (PMDD) is the most prevalent but neglected psychiatric disorder, with somatic symptoms severe enough to markedly affect usual daily activities and have a negative impact on mental health and quality of life by affecting females' behaviour and cognition. Studies regarding premenstrual dysphoric disorder and associated factors among high school students in low and middle income countries are limited.Therefore the aims of this study was to assess the prevalence and associated factors of PMDD among high school students and is pivotal in further investigation. Methods: A school-based cross-sectional study was conducted from March 25 to April 17, 2023 using a simple random sampling technique to select a sample of 564 participants. Premenstrual dysphoric disorder was assessed using the Diagnostic and Statistical Manual of Mental Disorders (DSM-5). Self-administered, standardised questionnaires were used to collect. Result: The total of 548 study participants were participated with a 97.2% response rate. The prevalence of premenstrual dysphoric disorder among high school students was found to be 33.03% with (95% CI 29.20, 37.09%). In multivariable analysis of irregular menstruation cycle (AOR=4. 242,95%CI=2.182,8.246), depression (AOR=5.272,95%CI=2.779, 10.002), having greater than four days' menstruation bleeding duration (AOR=2.138 95%CI=1.105, 4.138) and high perceived stress (AOR=3.468 95%CL=1.217, 9.880) were factors significantly associated with premenstrual dysphoric disorder.The overall prevalence of PMDD was one-third among high school students was high. Moreover, the long duration of menstruation bleeding, had depressive symproms, an irregular menstruation cycle, and high perceived stress were significant factors in PMDD. Therefore, it needs early screening and intervention in primary healthcare settings, especially for those who have high perceived stress, having depression , a long duration of menstruation bleeding, and an irregular menstruation cycle, so as to have good academic achievement and psychological wellbeing.