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ORIGINAL RESEARCH article

Front. Psychiatry
Sec. Addictive Disorders
Volume 15 - 2024 | doi: 10.3389/fpsyt.2024.1404050
This article is part of the Research Topic Adolescent Addictions and Risky Behaviors: Implications for Health View all 9 articles

Resting-state brain networks alterations in adolescents with Internet Gaming Disorder associate with cognitive control impairments

Provisionally accepted
Tao Zhao Tao Zhao Yibo Zhang Yibo Zhang Yange Li Yange Li *Jie Wu Jie Wu *Wang Ruiqi Wang Ruiqi Qiyan Lv Qiyan Lv *Dingyi Li Dingyi Li *Yan Lang Yan Lang *
  • First Affiliated Hospital of Zhengzhou University, Zhengzhou, China

The final, formatted version of the article will be published soon.

    Objective: Research indicates that cognitive control is compromised in individuals with internet gaming disorder (IGD). However, the neural mechanisms behind it are still unclear. This study aims to investigate alterations in resting-state brain networks in adolescents with IGD and the potential neurobiological mechanisms underlying cognitive dysfunction. Materials and Methods: A total of 44 adolescent IGD subjects (male/female: 38/6) and 50 healthy controls (male/female: 40/10) were enrolled. Participants underwent demographic assessments, Young's Internet Addiction Scale, Barratt Impulsiveness Scale 11 Chinese Revised Version, the Chinese Adolescents' Maladaptive Cognitions Scale, exploratory eye movement tests, and functional magnetic resonance imaging (fMRI). FMRI data were analyzed using the GIFT software for independent component analysis, focusing on functional connectivity within and between restingstate brain networks.Results: In comparison to the control group, impulsivity in adolescent IGD subjects showed a positive correlation with the severity of IGD (r=0.6350, p < 0.001), linked to impairments in the Executive Control Network (ECN) and a decrease in functional connectivity between the Salience Network (SN) and ECN (r=0.4307, p=0.0021; p=0.0034). Decreased resting state activity of the dorsal attention network (DAN) was associated with attentional dysregulation of IGD in adolescents (r=0.4071, p=0.0017), and ECN increased functional connectivity with DAN. The degree of IGD was positively correlated with enhanced functional connectivity between the ECN and DAN (r=0.4283, p=0.0037).Conclusions: This research demonstrates that changes in the ECN and DAN correlate with heightened impulsivity and attentional deficits in adolescents with IGD. The interaction between cognitive control disorders and resting-state brain networks in adolescent IGD is related.

    Keywords: Internet gaming disorder, adolescents, Independent Component Analysis, Resting-state brain networks, cognitive control

    Received: 20 Mar 2024; Accepted: 12 Aug 2024.

    Copyright: © 2024 Zhao, Zhang, Li, Wu, Ruiqi, Lv, Li and Lang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Yange Li, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China
    Jie Wu, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China
    Qiyan Lv, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China
    Dingyi Li, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China
    Yan Lang, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China

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