AUTHOR=Walsh Olivia A. , Wadden Thomas A. , Tronieri Jena Shaw , Chao Ariana M. , Pearl Rebecca L. TITLE=Weight Bias Internalization Is Negatively Associated With Weight-Related Quality of Life in Persons Seeking Weight Loss JOURNAL=Frontiers in Psychology VOLUME=Volume 9 - 2018 YEAR=2018 URL=https://www.frontiersin.org/journals/psychology/articles/10.3389/fpsyg.2018.02576 DOI=10.3389/fpsyg.2018.02576 ISSN=1664-1078 ABSTRACT=Research has shown a negative relationship between weight bias internalization (WBI) and general measures of health-related quality of life (QOL), such as the Short Form–36. Less is known about the impact of WBI on weight-specific domains of QOL. This study examined the relationship between WBI and weight-related QOL, as measured by the Impact of Weight on Quality of Life (IWQOL-Lite) scale. Participants were 178 adults with obesity (71.3% black, 87.6% female, mean body mass index [BMI]=40.9±5.9 kg/m2) enrolled in a weight loss trial testing the effects of lorcaserin on weight loss maintenance. At baseline, participants completed the Weight Bias Internalization Scale (WBIS), the IWQOL-Lite and the Patient Health Questionnaire (PHQ-9) to assess symptoms of depression. Total scores for the IWQOL-Lite and its five subscales (Physical Function, Self-Esteem, Sexual Life, Public Distress and Work) were calculated. The WBIS was negatively correlated with the IWQOL-Lite total and subscales scores (r values=-0.28 to -0.76, p values<0.001). Linear regression analyses showed that WBIS scores were associated with the IWQOL-Lite total score and all subscales above and beyond the effects of demographic variables, BMI, and depressive symptoms (beta values=-0.17 to -0.70, p values<0.03). The relationship between WBIS and the IWQOL-Lite scales did not differ by gender or race. WBI was associated with mental and physical aspects of weight-related QOL in a predominantly black and female treatment-seeking sample of patients with obesity. Prioritizing the development of interventions to reduce WBI may be important for improving weight-related QOL.