AUTHOR=Benassi Mariagrazia , Garofalo Sara , Ambrosini Federica , Sant’Angelo Rosa Patrizia , Raggini Roberta , De Paoli Giovanni , Ravani Claudio , Giovagnoli Sara , Orsoni Matteo , Piraccini Giovanni TITLE=Using Two-Step Cluster Analysis and Latent Class Cluster Analysis to Classify the Cognitive Heterogeneity of Cross-Diagnostic Psychiatric Inpatients JOURNAL=Frontiers in Psychology VOLUME=Volume 11 - 2020 YEAR=2020 URL=https://www.frontiersin.org/journals/psychology/articles/10.3389/fpsyg.2020.01085 DOI=10.3389/fpsyg.2020.01085 ISSN=1664-1078 ABSTRACT=The heterogeneity of cognitive profiles among psychiatric patients has been reported to carry significant clinical information. However, how to best characterize such cognitive heterogeneity is still a matter of debate. Despite being well suited for clinical data, cluster analysis techniques, like the Two-Step and the Latent Class, received little to no attention in the literature. The present study aimed to test the validity of the cluster solutions obtained with Two-Step and Latent Class cluster analysis on the cognitive profile of a cross-diagnostic sample of 387 psychiatric inpatients. Two-Step and Latent Class cluster analysis produced similar and reliable solutions. The overall results reported that it is possible to group all psychiatric inpatients into a Low and High Cognitive Profiles, with a higher degree of cognitive heterogeneity in Schizophrenia and Bipolar Disorder patients than in and Depressive Disorders Personality Disorder patients.