AUTHOR=Finol Héctor J. , Roschman-González Antonio 

TITLE=Ultrastructural Study on Tissue Alterations Caused by Trypanosomatids in Experimental Murine Infections

JOURNAL=Frontiers in Public Health

VOLUME=Volume 2 - 2014

YEAR=2014

URL=https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2014.00075

DOI=10.3389/fpubh.2014.00075

ISSN=2296-2565

ABSTRACT=The ultrastructural study in different tissues of mice experimentally infected with isolates of Trypanosoma evansi, Trypanosoma cruzi and Leishmania mexicana reveals changes in cardiac myocytes, skeletal muscle fibers and hepatic, adrenal, kidney and spleen cells. Some were cytoarchitectural changes and other consisted of necrosis. Alterations were also found in microvasculature.The mononuclear cell infiltrate included neutrophils, eosinophils and macrophages. This work shows that various mice tissues are important target for trypanosomatids.