AUTHOR=Bai Francesca , Tavelli Alessandro , Mulè Giovanni , Falcinella Camilla , Mondatore Debora , Tesoro Daniele , Barbanotti Diletta , Tomasoni Daniele , Castoldi Roberto , Augello Matteo , Allegrini Marina , Tagliaferri Gianmarco , Cona Andrea , Cozzi-Lepri Alessandro , Marchetti Giulia , d'Arminio Monforte Antonella TITLE=A Quantitative Estimate of the Expected Shortening of the Median Isolation Period of Patients With COVID-19 After the Adoption of a Symptom-Based Strategy JOURNAL=Frontiers in Public Health VOLUME=Volume 9 - 2021 YEAR=2021 URL=https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2021.639347 DOI=10.3389/fpubh.2021.639347 ISSN=2296-2565 ABSTRACT=A long period of isolation was observed in patients hospitalized for COVID-19 in Milan over March-September 2020 (45; IQR: 37-54 days). A significantly shorter period would have been observed by the application of May-WHO (22, IQR 17-30 days, p<0.001) and October-Italian (26, IQR 21-34 days, p<0.001) Guidelines. The adoption of the new symptom-based criteria is likely to lead to a significant reduction in the length of the isolation period with potential social, economic and psychological benefits, particularly in the younger population with mild/moderate disease and no comorbidities.