AUTHOR=Luo Kuan , Chen Yongfeng , Yang Junjie , Tao Quan , Luo Min 

TITLE=Liver Injury and Elevated Levels of Interleukins, Interleukin-2 Receptor, and Interleukin-6 Predict the Severity in Patients With COVID-19

JOURNAL=Frontiers in Public Health

VOLUME=Volume 9 - 2021

YEAR=2021

URL=https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2021.778340

DOI=10.3389/fpubh.2021.778340

ISSN=2296-2565

ABSTRACT=The novel coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread worldwide, and the World Health Organization (WHO) declared it a pandemic, on March 11, 2020. Clinical characteristics and epidemiology features of patients infected with SARS-cov-2 have been explored in many previous However, little is known about the combinative association of liver dysfunction and abnormal interleukins in severe patients with COVID-19. This study was designed to estimate whether liver dysfunction and abnormal interleukins could predict the severity of COVID-19. Our study integrated liver function data and interleukins data in COVID-19 patients and found that liver injury and two interleukins, IL-2R and IL-6, were closely related to the prognosis of patients with COVID-19. This study may give more exact information to clinicians about the prognosis of patients with COVID-19. In addition, this correlational research between liver disorder and interleukins, may provide a new vision to diagnosis and treatment in patients.