AUTHOR=Padilla-Rivas Gerardo R. , Delgado-Gallegos Juan Luis , Garza-Treviño Gerardo , Galan-Huerta Kame A. , G-Buentello Zuca , Roacho-Pérez Jorge A. , Santoyo-Suarez Michelle Giovana , Franco-Villareal Hector , Leyva-Lopez Ahidée , Estrada-Rodriguez Ana E. , Moreno-Cuevas Jorge E. , Ramos-Jimenez Javier , Rivas-Estrilla Ana M. , Garza-Treviño Elsa N. , Islas Jose Francisco TITLE=Association between mortality and cardiovascular diseases in the vulnerable Mexican population: A cross-sectional retrospective study of the COVID-19 pandemic JOURNAL=Frontiers in Public Health VOLUME=Volume 10 - 2022 YEAR=2022 URL=https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2022.1008565 DOI=10.3389/fpubh.2022.1008565 ISSN=2296-2565 ABSTRACT=Cardiovascular diseases (CVD´s) continue as the primary cause of death worldwide. During the past couple of years, and with the surge of the COVID-19 pandemic, deaths linked to CVD´s were -slightly overshadowed by those deaths related to COVID-19, albeit during the highest peaks of the pandemic. The present study derived from understanding the correlation between both diseases, from the standpoint of patients already diagnosed with CVD´s (n = 41883) and what comorbidities had the highest influence on overall patient death (n = 3637). Obesity, hypertension, and diabetes are all linked to worsening the outcome of COVID-19 positive patients, hence they were considered when looking at the overview of all CVD positive patients. Our finding showed that 1697 deaths were related to diabetes (p < 0.001), 987 deaths were related to obesity (p < 0.001), and lastly 2499 deaths were attributed to hyper-tension (p < 0.001) individually. Using logistic regression modeling, we found diabetes (OR: 1.744, p < 0.001) and hypertension (OR: 2.179, p < 0.001) had a high impact on patient deaths. Hence, having a CVD diagnosis, with hypertension and/or diabetes, seems to increase the likelyhood of complication leading to death in COVID-19 positive patients.