AUTHOR=Xu Yuan-Yi , Xie Jin , Yin Hao , Yang Fang-Fang , Ma Chun-Ming , Yang Bao-Yi , Wan Rui , Guo Bin , Chen Li-Dian , Li Song-Lin 

TITLE=The Global Burden of Disease attributable to low physical activity and its trends from 1990 to 2019: An analysis of the Global Burden of Disease study

JOURNAL=Frontiers in Public Health

VOLUME=Volume 10 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2022.1018866

DOI=10.3389/fpubh.2022.1018866

ISSN=2296-2565

ABSTRACT=Introduction: Low physical activity (LPA) is associated with several major noncommunicable diseases (NCDs) and premature mortality. In this study, we aimed to assess the global burden and trends in disease attributable to LPA (DALPA) from 1990 to 2019.
Methods: Annual age-standardised disability-adjusted life years (DALYs) and deaths rates of DALPA [all-cause and five specific causes (ischaemic heart disease, diabetes mellitus, stroke, colon and rectal cancer, and breast cancer)] by sex, age, geographical region and Social Deprivation Index (SDI) score from 1990 to 2019 were available from the Global Burden of Disease (GBD) study 2019. The estimated annual percentage changes (EAPCs) were calculated to quantify the changing trend. A generalised linear model (GLM) was used to explore the relationship between DALYs/deaths rates of DALPA and sociodemographic factors.
Results: Globally, in 2019, the age-standardised DALYs and deaths rates of DALPA were 198.42/100,000 (95% UI: 108.16/100,000-360.32/100,000) and 11.10/100,000 (95% UI: 5.66/100,000-19.51/100,000), respectively. There were 15.74 million (8.51–28.61) DALYs and 0.83 million (0.43-1.47) deaths attributable to LPA. Overall, age-standardised DALYs and deaths rates presented significant downward trends with EAPCs [-0.68% (95% CI: -0.85% to -0.50%) for DALYs and -1.00% (95% CI: -1.13% to -0.86%) for deaths] from 1990 to 2019. However, age-standardised DALYs and deaths rates of diabetes mellitus attributable to LPA were substantially increased [EAPC: 0.76% (95% CI: 0.70%-0.82%) for DALYs and 0.33% (95% CI: 0.21%-0.51%) for deaths]. In the 15-49 age group, DALPA presented significant upward trends [EAPC: 0.74% (95% CI: 0.58%-0.91%) for DALYs and 0.31% (95% CI: 0.1% -0.51%) for deaths]. The GLM revealed that higher gross domestic product and current health expenditure (% of GDP) were negatively associated with DALYs and deaths rates of DALPA.
Conclusion: Although global age-standardised DALYs and deaths rates of DALPA presented downward trends, they still cause a heavy burden worldwide. These rates showed upward trends in the diabetic and 15-49 age groups, which needs more attention and health interventions.