AUTHOR=Du Min , Yuan Jie , Jing Wenzhan , Liu Min , Liu Jue TITLE=The Effect of International Travel Arrivals on the New HIV Infections in 15–49 Years Aged Group Among 109 Countries or Territories From 2000 to 2018 JOURNAL=Frontiers in Public Health VOLUME=Volume 10 - 2022 YEAR=2022 URL=https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2022.833551 DOI=10.3389/fpubh.2022.833551 ISSN=2296-2565 ABSTRACT=Abstract Objective: The prevalent international travel may had an impact on new HIV infections, but related-studies were lacked. We aimed to explore the association between international travel arrivals and new HIV infections in 15 to 49 years aged group from 2000 to 2018, to make tailored implications for HIV prevention. Methods: We obtained the data of new HIV infections from the Joint United Nations Programme on HIV/AIDS and international travel arrivals from World Bank. Correlation analysis was used to explore the relation briefly. Log-linear models were built to analyze the association between international travel arrivals and new HIV infections. Results: International travel arrivals were positively correlated with new HIV infections (Correlation coefficients: 0.916, P<0.001). After controlling population density, median age of the total population (years), SDI, travel-related mandatory HIV testing and HIV-related restrictions and antiretroviral therapy coverage, there were 6.61% (95% CI: 5.73, 7.50; P<0.001) percentage changes in new HIV infections of 15 to 49 years aged group associated with a 1 million increase in international travel arrivals. Conclusions: Higher international travel arrivals were correlated with new HIV infections in 15 to 49 years aged group. Therefore, multipronged structural and effective strategies and management should be implemented and strengthened.