AUTHOR=Dong Chen , Yu Zhou , Quan Xin , Wei Siming , Wang Jiayang , Ma Xianjie TITLE=No Differences in Wound Healing and Scar Formation Were Observed in Patients With Different COVID-19 Vaccination Intervals JOURNAL=Frontiers in Public Health VOLUME=Volume 10 - 2022 YEAR=2022 URL=https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2022.883113 DOI=10.3389/fpubh.2022.883113 ISSN=2296-2565 ABSTRACT=Background: Safety concerns are one of the most common reasons for COVID-19 vaccination refusal. In the field of plastic and reconstructive surgery, whether COVID-19 vaccination influences wound healing and scar formation is worthy of special attention. Methods: In this study, adult trauma patients with subcutaneous suture placed by a single plastic surgeon in a single center were included. The vaccination interval was defined as the interval between the last dose of COVID-19 vaccine and when surgical sutures were introduced. The patients were categorized by vaccination interval into three groups of <1 month, 1–3 months, and ≥3 months. Wound healing and scar formation were rated according to the Wound Assessment Inventory (WAI) and Patient and Observer Scar Assessment Scale (POSAS) in the groups at 7 days and after a 3-month follow-up. Results: All total and individual scores of WAI and POSAS were not significantly different among the groups. Conclusion: No differences in wound healing and scar formation were observed in patients with different COVID-19 vaccination intervals. Thus, it is not necessary to postpone COVID-19 vaccination, as the vaccine does not affect wound healing and scar formation in patients undergoing surgery. This study aimed to eliminate concerns and hesitancy in receiving the COVID-19 vaccine.