AUTHOR=Solís-Díez Gerard , Turu-Pedrola Marta , Roig-Izquierdo Marta , Zara Corinne , Vallano Antoni , Pontes Caridad TITLE=Dealing With Immunoglobulin Shortages: A Rationalization Plan From Evidence-Based and Data Collection JOURNAL=Frontiers in Public Health VOLUME=Volume 10 - 2022 YEAR=2022 URL=https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2022.893770 DOI=10.3389/fpubh.2022.893770 ISSN=2296-2565 ABSTRACT=Background: The demand and consumption of immunoglobulins (IgGs) is growing, and there are more and more difficulties to obtain supplies. The aim of the study was to analyse the evolution of IgGs consumption and cost over a decade, to describe the measures implemented for clinical management in the context of a regional public health system, and to evaluate the initial impact of these measures. Methods: We performed a retrospective longitudinal study including patients of all public health system in Catalonia. Firstly, we analysed data consumption and cost of IgGs during a period between January 1, 2010 and December 31, 2021. Secondly, we analysed the impact of a set of regional measures in terms of annual consumption and cost of IgGs. Regional measures were based....