AUTHOR=Xu Haijiang , Guo Ruixia , Yang Yantao 

TITLE=Effects of Osimertinib Combined With Pulmonary Rehabilitation and Health Care Training on Pulmonary Function, Complications, and Quality of Life in Patients After Radical Resection of Lung Cancer

JOURNAL=Frontiers in Public Health

VOLUME=Volume 10 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2022.911377

DOI=10.3389/fpubh.2022.911377

ISSN=2296-2565

ABSTRACT=Objective. To explore the effects of osimertinib combined with the pulmonary rehabilitation and health care training on pulmonary function, complications and the quality of life (QOL) in patients after radical resection of lung cancer. Methods. The data of 120 patients with radical resection of lung cancer admitted to The First Affiliated Hospital of Zhengzhou University from February 2020 to February 2021 were retrospectively analyzed. According to the order of admission, they were equally divided into group p and group q. All patients were given the pulmonary rehabilitation and health care training, and group p was treated with the osimertinib, while group q received the treatment of pemetrexed combined with cisplatin. The pulmonary function, the incidence of complications and QOL between the two groups were compared. Results. Compared with group q, the pulmonary function was obviously higher (P<0.001), the incidence of complications was significantly lower (P<0.05), and QOL scores were markedly higher in group p after treatment (P<0.001). Conclusion. The combination of osimertinib and the pulmonary rehabilitation and health care training can improve the pulmonary function of non-small cell lung cancer (NSCLC) patients with radical resection of lung cancer, and reduce their postoperative morbidity, thereby improving their QOL, which is conducive to reducing the patients' and social medical burden.