AUTHOR=Sun Yufang , Dai Hang , Wang Ping , Zhang Xiaodong , Cui Dongliang , Huang Yongping , Zhang Jimei , Xiang Tao 

TITLE=Will People Accept a Third Booster Dose of the COVID-19 Vaccine? A Cross-Sectional Study in China

JOURNAL=Frontiers in Public Health

VOLUME=Volume 10 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2022.914950

DOI=10.3389/fpubh.2022.914950

ISSN=2296-2565

ABSTRACT=Coronavirus disease-2019 (COVID-19) vaccines are considered to be effective weapons to prevent the spread of severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) infection. We previously reported that only one-third of healthcare workers(HCW) in China were willing to receive the vaccine when it became available.Here,we examined the attitudes toward a third booster dose among Chinese people and determined the influencing factors.
This was a cross-sectional online survey and the snowball sampling method was utilized.An online questionnaire was provided to all participants in the form of a QR code.The questionnaire gathered general demographic information,views on vaccines and included the General Health Questionnaire (GHQ-12); Depression, Anxiety, and Stress Scales (DASS-21). The data were collected automatically and electronically. Univariate analysis was done between all the variables and our dependent variable.Multivariable logistic regression models were employed to examine and identify the associations between the acceptance of the third booster dose with the associated variables.
We collected 1062 complete answers. Of these, 90.39% (n = 960) declared they would accept a booster dose. Knowing more about the vaccine and recognition of the efficacy of vaccines were associated significantly with greater acceptance of a booster dose. People willing to take a booster dose had better psychological health. A belief that a booster dose could prevent severe SARS-CoV-2 infection and could enhance this effect of the first two doses were the main contributing factors to vaccine acceptance. Vaccine hesitancy was due mainly to a perceived low risk of SARS-CoV-2 infection and rapid mutation of SARS-CoV-2.
The acceptance of the third booster dose was significantly improved compared with the first two doses in previous studies.More positive attitudes regarding a COVID-19 vaccine were helped by its efficacy and few side-effects.