AUTHOR=Miao Yudong , Zhang Wanliang , Li Yi , Wu Jian , Xu Dongyang , Gu Jianqin , Wang Meiyun , Wei Wei , Ye Beizhu , Miao Chengyuan , Tarimo Clifford Silver , Dong Wenyong TITLE=Association between lifestyle and COVID-19 vaccination: A national cross-sectional study JOURNAL=Frontiers in Public Health VOLUME=Volume 10 - 2022 YEAR=2022 URL=https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2022.918743 DOI=10.3389/fpubh.2022.918743 ISSN=2296-2565 ABSTRACT=Objective: To assess lifestyles, COVID-19 vaccination coverage rates and the relationships between lifestyles and COVID-19 vaccination among Chinese population. Methods: We collected data on socio-demographics, perception of COVID-19 pandemic, lifestyles, and self-reported COVID-19 vaccination via an online survey in China. The Chi-square goodness-of-fit test was used to monitor sample saturation throughout the formal online survey. Binary logistic regression analyses were conducted to examine the association between COVID-19 vaccination rate and lifestyle score. We assigned values to 12 lifestyles ranging from positive to negative, with positive lifestyles receiving a higher score and negative receiving a lower score, ranging from 1 to 5. For each participant, the total lifestyle scored from 12 to 56. Restricted cubic spline (RCS) was used to visualize the trends and correlations between lifestyle score and COVID-19 vaccination coverage. Propensity Score Matching (PSM) was used to explore the association between specific lifestyles and COVID-19 vaccination. Results: A total of 29925 participants (51.4% females) responded. The lifestyle score of the sample was 44.60±6.13 (scoring range:12 to 56). COVID-19 vaccination rate was found to be 89.4% (89.1%-89.8%). Female participants reported a higher vaccination rate than males (91.5% versus 87.1%). Compared to Q1, COVID-19 vaccination coverage rates increased with lifestyle total scores [ORQ2=1.901 (1.718-2.103), P<0.001; ORQ3=2.373 (2.099-2.684), P<0.001; ORQ4=3.765 (3.209-4.417), P<0.001]. After applying PSM, it was determined that all 12 specific healthy lifestyles analyzed, including maintaining a healthy body weight, a healthy diet, regular physical exercises, adequate sleep, regular physical examination and others, were found to be positive factors for COVID-19 vaccination. Conclusion: The majority of mainland Chinese lived a healthy lifestyle throughout the pandemic, and the rate of COVID-19 vaccination was high. Specific healthy lifestyles contributed to COVID-19 vaccination coverage rates significantly. According to the study's findings, global efforts to achieve herd immunity should be prioritized by continually promoting healthy lifestyles and improving public perception of COVID-19 vaccines.